Journal of Oral Implantology September 2012 - (Page 527)

CASE REPORT Peripheral Giant Cell Granuloma Associated With Dental Implants: Clinical Case and Literature Review ˜ Maria A. Penarrocha-Diago* Juan Cervera-Ballester, DDS ´ Laura Maestre-Ferrın, DDS ˜ David Penarrocha-Oltra, DDS Peripheral giant cell granuloma (PGCG) associated to dental implants is a very infrequent peri-implant soft-tissue complication, with only 11 cases recorded in the literature to date. The present study describes a 54-year-old woman presenting a swelling of the alveolar margin in the fourth quadrant in relation to a fixed prosthesis cemented over implants. Treatment consisted of complete resection of the lesion with implantoplasty of the exposed implant threads. The diagnosis of PGCG was confirmed by histological study, and no relapse has been recorded after 12 months of follow-up. Key Words: peripheral giant cell granuloma, dental implants, complications INTRODUCTION eripheral giant cell granuloma (PGCG) is a reactive exophytic lesion1 classified as a benign tumor of the oral mucosa. Peripheral giant cell granuloma originates from the periosteum or periodontal ligament.2 The etiology is unclear, although a locally acting irritative factor or chronic traumatic mechanism might be involved.2–4 The lesion may appear at any age, with a maximum incidence between the fifth and sixth decades of life, and it exhibits a slight female predominance.3–7 The clinical appearance is similar to that of pyogenic granuloma, that is, a fleshy, soft, sessile or pediculate mass with a color ranging from dark red to purple, located on the attached gums1 or on the mucosa of the alveolar margin.6 Peripheral giant cell granuloma tends to bleed and can erode the underlying alveolar bone.8 It is most often observed in the posterior regions of the mandible.4 The appearance of PGCG associated to dental implants is rare, with only 11 cases reported in the literature to date.8–14 Both the appearance and Valencia University Medical and Dental School, Valencia, Spain. * Corresponding author, e-mail: maria.penarrocha@uv.es DOI: 10.1563/AAID-JOI-D-11-00143 P diagnosis of the lesion are the same as in patients without implants. CLINICAL CASE A 54-year-old woman presented with a swelling of the alveolar margin in the fourth quadrant in relation to a fixed prosthesis cemented over implants. Five years before, the patient underwent upper fixed rehabilitation with 8 dental implants (Centerpulse, Centerpulse Dental Inc), followed 2 years later by postextraction implant surgery in the lower arch for rehabilitation with a cemented fixed prosthesis over 7 Defcon Avantblast TSA surface implants (Impladent, Sentmenat, Barcelona, Spain). Intraoral exploration revealed an elastic, exophytic, and nonulcerated lesion measuring about 2 cm in diameter. The lesion was of hard consistency, with a smooth and shiny surface and a reddish-blue color, located between 2 implants in the right lower region at the level of the second premolar and first molar (Figure 1a and b). There was no bleeding in response to probing, although a pouch depth of about 3 mm was recorded around both of the mentioned implants. The implants were osteointegrated, with no mobility or symptoms. Journal of Oral Implantology 527

Table of Contents for the Digital Edition of Journal of Oral Implantology September 2012

American Academy of Implant Dentistry Foundation Supports Basic and Clinical Research
Evaluation of 3- to 8-Year Treatment Outcomes and Success Rates With 6 Implant Brands in Partially Edentulous Patients
Histometric Analysis of Bone Repair in Bone-Implant Interface Using a Polylactic/ Polyglycolic Acid Copolymer Associated With Implants in Rabbit Tibia
Fold-Over Flap Technique for Developing the Facial Gingival Contour: A Case Report
Rehabilitation of the Atrophic Posterior Maxilla With Pterygoid Implants: A Review
Immediate Loading of Maxillary and Mandibular Implant-Supported Fixed Complete Dentures: A 1- to 10-Year Retrospective Study
Immediate Loading of Single Post-Extractive Implants in the Anterior Maxilla: 12-Month Results From a Multicenter Clinical Study
Immediate Implants After Enucleation of an Odontogenic Keratocyst: An Early Return to Function
Effects of Different Abutment Connection Designs on the Stress Distribution Around Five Different Implants: A 3-Dimensional Finite Element Analysis
Implant-Prosthetic Rehabilitation of a Patient with Nonsyndromic Oligodontia: A Clinical Report
Planning for Immediate Loading of Implant-Supported Prostheses: Literature Review
Development of a Rat Model of Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ)
Anorganic Bovine-Derived Hydroxyapatite vs β-Tricalcium Phosphate in Sinus Augmentation: A Comparative Histomorphometric Study
Peripheral Giant Cell Granuloma Associated With Dental Implants: Clinical Case and Literature Review
Bilateral Vertical Ridge Augmentation With Block Grafts and Guided Bone Regeneration in the Posterior Mandible: A Case Report
Cell Culture–Based Tissue Engineering as an Alternative to Bone Grafts in Implant Dentistry: A Literature Review

Journal of Oral Implantology September 2012