Journal of Oral Implantology December 2013 - (Page 643)

RESEARCH Tensile Resistance of Mineralized and Demineralized Rat Bones in Different Regions (Calvarial and Femur) Jefferson Tomio Sanada, DDS, MSc1 Jefferson Ricardo Pereira, DDS, MSc, PhD2* Aliana Mayumi Ferreira Assaoka, DDS1 Ana Cristina de Godoi Zingra, DDS1 ´sar Garcia de Oliveira, DDS, MSc, PhD1 Pedro Ce ´ Accacio Lins do Valle, DDS, MSc, PhD1 The aim of this study was to evaluate the tensile resistance of mineralized and demineralized bones. Twelve mice were used. Specimens were collected and divided into groups 1 and 2, mineralized and demineralized calvarial bone, and groups 3 and 4, mineralized and demineralized femoral bone. There was not a statistically significant difference (analysis of variance) between the regions; however, when comparing the demineralized and mineralized groups, a statistically significant difference (Student test) for the mineralized group was noticed. Key Words: bone, biomaterial, tensile strength INTRODUCTION W hen there is tooth loss due to caries, periodontal disease, trauma, trepanation, or endodontal lesions among other reasons, a physiological process of bone resorption in height or thickness is triggered in the area, which is called alveolar ridge resorption.1-3 This bone remodeling affects the functioning of any prosthesis supported on the residual alveolar ridge and impairs prosthetic rehabilitation of patients either with complete dentures, removable partial dentures, or implant-supported dentures (affixed or removable). Because of this difficulty, the literature has demonstrated that the use of biomaterials to fill up the sockets after tooth extraction may contribute to the maintenance of the alveolar ridge in both height and thickness1-3; the advances in medical and dental technology have led to an increase in 1 ˜ ˜ Bauru Dental School, University of Sao Paulo, Sao Paulo, Brazil. Dental School, University of Southern Santa Catarina-UNISUL, Santa Catarina, Brazil. *Corresponding author, e-mail: jeffripe@rocketmail.com DOI: 10.1563/AAID-JOI-D-10-00091 2 the development of biomaterials within the context of bone resorption caused by tooth extraction. Several biomaterials are commercially available, and indications vary according to their mechanism of action and origin. These biomaterials have been submitted to several laboratory evaluations (animal and human studies) before being introduced into the market. The calvaria of rats is an experimental model used to evaluate the repair of grafted areas; this model comprises creation of defects in calvarias and filling them with different biomaterials for evaluation of their biocompatibility, repair time, cell type, and quality and quantity of newly formed bone tissue among others. Defects in calvarias of rats may be classified into 2 types: critical (greater than 6-mm diameter) or noncritical (smaller than 6-mm diameter).4-12 Creation of a critical-size defect is indicated when the biomaterial might have the ability of induction and/ or conduction to bone formation in cases without natural closure of this area (ie, the biomaterial would be able to induce and/or conduct bone formation beyond the physiological repair capacity of the organism). In this type of study, animals are killed at different periods to allow histological and radiographic follow-up of bone repair, thus allowing quantification of the period of repair of the defect. Journal of Oral Implantology 643

Table of Contents for the Digital Edition of Journal of Oral Implantology December 2013

Blade-Form Dental Implants: FDA Reclassification as a Class II Dental Implant Device
Effect of Different Storage Media on the Regenerative Potential of Autogenous Bone Grafts: A Histomorphometrical Analysis in Rabbits
Tensile Resistance of Mineralized and Demineralized Rat Bones in Different Regions (Calvarial and Femur)
Microbial Diversity of Peri-Implant Biofilms on Implant Fixed Bar and Telescopic Double Crown Attachments
Evidence-Based Techniques to Assess the Performance of Dental Implants
Influence of Platform and Abutment Angulation on Peri-Implant Bone. A Three- Dimensional Finite Element Stress Analysis
Direct Current Electric Stimulation in Implant Osseointegration: An Experimental Animal Study With Sheep
Prevalence of Sinus Augmentation Associated With Maxillary Posterior Implants
The Bactericidal Effects of an Acidified Sodium Chlorite-Containing Oral Moisturizing Gel: A Pilot Study
Influence of Fine Threads and Platform-Switching on Crestal Bone Stress Around Implant— A Three-Dimensional Finite Element Analysis
An Evaluation of the Resonance Frequency Analysis Device: Examiner Reliability and Repeatability of Readings
Histologic and Histomorphometric Assessment of Implants and Periapical Tissues When Placed in the Sockets of Extracted Teeth, Teeth With Periapical Lesions, and Healed Lesions: A Canine Study
Microbiological Aspects of Human Mandibular Subperiosteal Dental Implants
A Technique for Removal of a Fractured Implant Abutment Screw
Eight-Year Results of Site Retention of Anorganic Bovine Bone and Anorganic Bovine Matrix
A Reactive Lesion (Pyogenic Granuloma) Associated With Dental Implant: A Case Report
Twelve-Year Clinical and Radiological Results of Maxillary and Mandibular Implant- Retained Bar Overdentures Carried out on Oxidized (TiUnite) Replace Select Implants: A Clinical Case
PEEK Dental Implants: A Review of the Literature

Journal of Oral Implantology December 2013

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