Journal of Oral Implantology May 2013 - (Page 256)

RESEARCH Effect of Platelet-Rich Plasma on the Outcome of Early Loaded Dental Implants: A 3-Year Follow-up Study Gulfem Ergun, DDS, PhD1* Ferhan Egilmez, DDS, PhD1 Isil Cekic-Nagas, DDS, PhD1 ˙nci Rana Karaca, DDS, PhD2 I Suleyman Bozkaya, DDS, PhD2 This study evaluated the effect of local application of platelet-rich plasma (PRP) on the outcome of early loaded implants. Two implants were placed in the posterior region or bilaterally symmetric to the median line of the maxilla. Then, PRP was either applied or not applied to the implant sockets. Outcome measures were prosthesis and implant success as well as biological and prosthetic complications. Stability of individual implants was assessed manually and with a resonance frequency analysis device. The implant stability quotient (ISQ) was recorded on the operation day, on postoperative day 4, and at postoperative week 1. At the end of the first postoperative week, implants with ISQ values .60 were early loaded on day 7 with metal-ceramic crowns. Measurements were repeated at postoperative weeks 2, 3, and 4 and at postoperative months 6, 12, 24, and 36. One of the 64 implants was dropped out after 3 months of loading. No prosthesis failed. There were no prosthetic complications. Statistical analysis revealed significant differences between ISQ values of PRP and nonPRP implants on the operation day. Moreover, no statistically significant differences were found between ISQ values of PRP and non-PRP implants in the follow-up periods (P . .05). No appreciable clinical effect was observed when using PRP in the maxilla. Key Words: primary stability, resonance frequency analysis, platelet-rich plasma INTRODUCTION O ral implants have exhibited high predictability in supporting fixed prosthetic rehabilitations, provided that certain conditions are met during surgical placement and heal1,2 According to the conventional 2-stage ing. implant protocol for maxillary implants, a healing time of 6 months without loading is considered to be the key for successful osseointegration.3,4 For edentulous patients, shortening this time and thus avoiding a long period of wearing transitional removable prosthesis is advantageous for esthetic, 1 Gazi University, Faculty of Dentistry, Department of Prosthodontics, Ankara, Turkey. 2 Gazi University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Ankara, Turkey. * Corresponding author, e-mail: gulfem@gazi.edu.tr DOI: 10.1563/AAID-JOI-D-11-00151 256 Vol. XXXIX /Special Issue /2013 economical, and psychological reasons.5 The good outcome of 1-stage surgery and early implant loading may be due to the dense bone of the mandible and the ease in obtaining secure primary implant stability.6 Primary implant stability is considered an important parameter for determining the loading protocol.7 Although there is no gold standard for measuring implant stability,8 several methods have been proposed: clinical assessment by exerting lateral forces with 2 opposing mirror handles, percussion, use of a Dental Fine Tester, and a Periotest device.9,10 Furthermore, the use of resonance frequency analysis (RFA) to assess implant stability has been validated by several authors.11 Previous studies have reported the use of RFA to measure stability of the implant–tissue interface at implant placement and determine the possibility of monitoring change in tissue stiffness

Table of Contents for the Digital Edition of Journal of Oral Implantology May 2013

Implantology: Inter-Dependent Worldwide Relationships
Use of Osteotomes for Implant Bed Preparation-Effect on Material Properties of Bone and Primary Implant Stability
The Effects of a Static Magnetic Field on Bone Formation Around a Sandblasted, Large-Grit, Acid-Etched-Treated Titanium Implant
Effect of Platelet-Rich Plasma on the Outcome of Early Loaded Dental Implants: A 3-Year Follow-up Study
Flapless Dental Implant Surgery for Patients on Oral Anticoagulants-The "WarLess Procedure": A Report of 2 Cases
Radiographic Evaluation of Narrow-Diameter Implants After 5 Years of Clinical Function: A Retrospective Study
Histomorphometry of 2 Immediately Loaded Mini Implants Retrieved From Human Mantible After 3 Months: A Light and Scanning Electron Microscopy Report
Splinted Zirconia Fixed Partial Denture Supported by Small Diameter (Mini Implants) in the Posterior Mandible: A Case Letter

Journal of Oral Implantology May 2013