Journal of Oral Implantology October 2014 - (Page 593)

CASE REPORT Full-Mouth Rehabilitation for a Patient With Dentinogenesis Imperfecta: A Clinical Report Sompop Bencharit, DDS, MS, PhD1* Michael B. Border, BS2 C. Russell Mack, BS2 Warren C. Byrd, BS2 John T. Wright, DDS, MS3 Dentinogenesis imperfecta (DI) is a genetic disorder affecting the structural integrity of the dentin that can result in weakened dentin. The affected teeth, especially posterior teeth, often need to be extracted due to severe wear or fracture. This frequently yields a loss of posterior occlusion and occlusal vertical dimension. Besides wear and fracture, anterior teeth often have an unesthetic appearance because of discoloration. Current treatments of choice, including composite bonding restorations and, more recently, all-ceramic restorations, are typically suggested to preserve the remaining teeth and tooth structure. However, there are a limited number of studies on dental implants in patients with DI. The effectiveness of dentin bonding and dental implants in patients with DI is not known. This clinical report describes a 32-year-old Asian woman with DI who underwent full-mouth rehabilitation. The posterior occlusion, mostly in the molar areas, was restored with dental implants and ceramometal restorations. The anterior teeth and premolars were restored with bonded lithium disilicate glass-ceramic pressed veneers and crowns made with computer-aided design/computer-aided manufacturing. This case demonstrates that restoring functional occlusion and esthetics for a patient with DI can be completed successfully using contemporary implant therapy and adhesive dentistry. Key Words: all ceramic, dental implants, dentinogenesis imperfecta, full-mouth rehabilitation, veneers INTRODUCTION D entinogenesis imperfecta (DI) type II (OMIM #125490), also known as hereditary opalescent dentin, is a genetic disorder affecting the development of the dentin. The DI condition typically affects both primary and permanent dentition. The prevalence of DI is estimated to be about 1 in 6000 to 8000 people.1 The DI condition often causes tooth discoloration ranging from an 1 Department of Prosthodontics, School of Dentistry, and Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, NC. 2 Department of Dental Research, School of Dentistry, University of North Carolina, Chapel Hill, NC. 3 Department of Pediatric Dentistry, School of Dentistry, University of North Carolina, Chapel Hill, NC. * Corresponding author, e-mail: Sompop_Bencharit@dentistry. unc.edu DOI: 10.1563/AAID-JOI-D-12-00217 opalescent blue gray to dark yellow brown. Because of the weakened dentinal structure, patients with DI often present with severely worn dentition, loss of tooth structure, missing teeth, and loss of occlusal vertical dimension. In addition, DI-affected teeth present with short and constricted roots as well as pulpal obliteration due to dentin hypertrophy. Although enamel in patients with DI most often appears normal in thickness and radiopacity, the underlying defective dentin often causes detachment of enamel. Exposed defective dentin is prone to severe wear. Tooth-to-tooth clinical variations due to variable expressivity within a person are common. The DI condition is classified into 3 types based on the affected dentin and bone. Type I is of the dental phenotype associated with osteogenesis imperfecta (OI) (OMIM #166200), which is most commonly caused by genetic mutations of genes Journal of Oral Implantology 593

Table of Contents for the Digital Edition of Journal of Oral Implantology October 2014

New AAIP Affiliates Increase JOI Readership
Letter to the Editor
Bone Response From a Dynamic Stimulus on a One-Piece and Multi-Piece Implant Abutment and Crown by Finite Element Analysis
Effect of Platelet-Rich Plasma on the Healing of Mandibular Defects Treated With Fresh Frozen Bone Allograft: A Radiographic Study in Dogs
Efficacy of Growth Factor in Promoting Early Osseointegration
Assessment of Candida Species Colonization and Denture-Related Stomatitis in Bar- and Locator-Retained Overdentures
A Simple Solution for Vector Control in Vertical Alveolar Distraction Osteogenesis
Maxillary Ridge Augmentation With Custom-Made CAD/CAM Scaffolds. A 1-Year Prospective Study on 10 Patients
A Retrospective 3- to 5-Year Study of the Reconstruction of Oral Function Using Implant- Supported Prostheses in Patients With Hypohidrotic Ectodermal Dysplasia
Effects of a New Implant Abutment Design on Peri-Implant Soft Tissues
Repair Technique for Fractured Implant-Supported Metal-Ceramic Restorations: A Clinical Report
Full-Mouth Rehabilitation for a Patient With Dentinogenesis Imperfecta: A Clinical Report
New Method to Increase Inter-alveolar Height With Preservation of Crestal Cortical Bone for Implant Treatment
Implant Placement With a Guided Surgery System Based on Stress Analyses Utilizing the Bone Density: A Clinical Case Report
A Novel Technique for Osteotome Internal Sinus Lifts With Simultaneous Placement of Tapered Implants to Improve Primary Stability
Maxillary Sinus Augmentation and Implant Placement Using Venous Blood Without Graft Material: A Case Letter
Modification of Maxillary Sinus Floor With Orthodontic Treatment and Implant Therapy: A Case Letter
A Surgical Guide for Optimal Placement and Immediate Restoration of Implant
Osseointegrated Dental Implants in Growing Children: A Literature Review

Journal of Oral Implantology October 2014