Dentaltown April 2018 - 89
Disrupting Biofilm:
Beyond Antibiotics
Hydrogen peroxide treatment demonstrates decrease in bacterial infections
by Milton Marshall, PhD, DABT, and
Tanya Dunlap, PhD
Toxicologist and biochemist
Milton Marshall, PhD, DABT,
researched safety data on the
use of hydrogen peroxide in
dentistry, which was presented
to the FDA and ADA. He has
also worked to examine the
biocompatibility and safety of
dental materials.
Tanya Dunlap, PhD, is the managing
director for Perio Protect, where
she has worked since 2005. She
coordinates clinical research
involving prescription tray delivery.
She also offers CE courses on
the science behind prescription
tray delivery and the important
implications of the research data.
88
APRIL 2018 // dentaltown.com
A
ntibiotics are a staple in dental offices to counter bacterial
infections. For the treatment of
periodontal disease, antibiotics
have been widely used to fight
gingival infections and the resulting inflammatory responses, and the antibiotics can
help. Efficacy is often short-lived, however,
because periodontitis is a biofilm-based
disease that, like other biofilm infections,
is refractory to antibiotics.1 Nevertheless,
the underlying problem is inflammation
prompted from a bacterial infection, and
we are taught that antibiotics are the right
course. When they don't work well or when
the results are not long-lasting, we often
think that we just need the right antibiotic.
But what if antibiotics aren't the best option?
Paradigms that shape our views are
often so ingrained that we don't realize how
they frame our thoughts-or our treatment
approaches. It's time to challenge the antibiotic treatment default for periodontal
therapy. This means not that antibiotics
shouldn't be used but that they need to be
used more judiciously.2
The underlying premise of the challenge:
If our current mechanical, surgical and
antibiotic treatments worked well, then
47 percent of American adults would not
have chronic periodontitis. But they do,
and millions more have gingivitis.3 We
want to find fault with patients, and home
care is a clear fault line where most patients
http://www.dentaltown.com
Table of Contents for the Digital Edition of Dentaltown April 2018
Dentaltown April 2018 - Intro
Dentaltown April 2018 - Cover1
Dentaltown April 2018 - Cover2
Dentaltown April 2018 - 1
Dentaltown April 2018 - 2
Dentaltown April 2018 - 3
Dentaltown April 2018 - 4
Dentaltown April 2018 - 5
Dentaltown April 2018 - 6
Dentaltown April 2018 - 7
Dentaltown April 2018 - 8
Dentaltown April 2018 - 9
Dentaltown April 2018 - 10
Dentaltown April 2018 - 11
Dentaltown April 2018 - 12
Dentaltown April 2018 - 13
Dentaltown April 2018 - 14
Dentaltown April 2018 - 15
Dentaltown April 2018 - 16
Dentaltown April 2018 - 17
Dentaltown April 2018 - 18
Dentaltown April 2018 - 19
Dentaltown April 2018 - 20
Dentaltown April 2018 - 21
Dentaltown April 2018 - 22
Dentaltown April 2018 - 23
Dentaltown April 2018 - 24
Dentaltown April 2018 - 25
Dentaltown April 2018 - 26
Dentaltown April 2018 - 27
Dentaltown April 2018 - 28
Dentaltown April 2018 - 29
Dentaltown April 2018 - 30
Dentaltown April 2018 - 31
Dentaltown April 2018 - 32
Dentaltown April 2018 - 33
Dentaltown April 2018 - 34
Dentaltown April 2018 - 35
Dentaltown April 2018 - 36
Dentaltown April 2018 - 37
Dentaltown April 2018 - 38
Dentaltown April 2018 - 39
Dentaltown April 2018 - 40
Dentaltown April 2018 - 41
Dentaltown April 2018 - 42
Dentaltown April 2018 - 43
Dentaltown April 2018 - 44
Dentaltown April 2018 - 45
Dentaltown April 2018 - 46
Dentaltown April 2018 - 47
Dentaltown April 2018 - 48
Dentaltown April 2018 - 49
Dentaltown April 2018 - 50
Dentaltown April 2018 - 51
Dentaltown April 2018 - 52
Dentaltown April 2018 - 53
Dentaltown April 2018 - 54
Dentaltown April 2018 - 55
Dentaltown April 2018 - 56
Dentaltown April 2018 - 57
Dentaltown April 2018 - 58
Dentaltown April 2018 - 59
Dentaltown April 2018 - 60
Dentaltown April 2018 - 61
Dentaltown April 2018 - 62
Dentaltown April 2018 - 63
Dentaltown April 2018 - 64
Dentaltown April 2018 - 65
Dentaltown April 2018 - 66
Dentaltown April 2018 - 67
Dentaltown April 2018 - 68
Dentaltown April 2018 - 69
Dentaltown April 2018 - 70
Dentaltown April 2018 - 71
Dentaltown April 2018 - 72
Dentaltown April 2018 - 73
Dentaltown April 2018 - 74
Dentaltown April 2018 - 75
Dentaltown April 2018 - 76
Dentaltown April 2018 - 78
Dentaltown April 2018 - 79
Dentaltown April 2018 - 80
Dentaltown April 2018 - 81
Dentaltown April 2018 - 82
Dentaltown April 2018 - 83
Dentaltown April 2018 - 84
Dentaltown April 2018 - 85
Dentaltown April 2018 - 86
Dentaltown April 2018 - 87
Dentaltown April 2018 - 88
Dentaltown April 2018 - 89
Dentaltown April 2018 - 90
Dentaltown April 2018 - 91
Dentaltown April 2018 - 92
Dentaltown April 2018 - 93
Dentaltown April 2018 - 94
Dentaltown April 2018 - 95
Dentaltown April 2018 - 96
Dentaltown April 2018 - 97
Dentaltown April 2018 - 98
Dentaltown April 2018 - 99
Dentaltown April 2018 - 100
Dentaltown April 2018 - 101
Dentaltown April 2018 - Cover3
Dentaltown April 2018 - Cover4
https://www.nxtbook.com/farran/dentaltown/dentaltown-april-2024
https://www.nxtbook.com/farran/dentaltown/dentaltown-march-2024
https://www.nxtbook.com/farran/dentaltown/dentaltown-february-2024
https://www.nxtbook.com/farran/dentaltown/dentaltown-january-2024
https://www.nxtbook.com/farran/dentaltown/dentaltown-december-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-november-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-new-grad-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-october-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-september-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-august-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-july-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-june-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-may-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-april-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-march-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-february-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-january-2023
https://www.nxtbook.com/farran/dentaltown/dentaltown-december-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-november-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-october-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-new-grad-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-september-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-august-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-july-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-june-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-may-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-april-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-march-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-february-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-january-2022
https://www.nxtbook.com/farran/dentaltown/dentaltown-december-2021
https://www.nxtbook.com/farran/dentaltown/dentaltown-november-2021
https://www.nxtbook.com/farran/dentaltown/dentaltown-new-grad-2021
https://www.nxtbook.com/farran/dentaltown/dentaltown-october-2021
https://www.nxtbook.com/farran/dentaltown/dentaltown-september-2021
https://www.nxtbook.com/farran/dentaltown/dentaltown-august-2021
https://www.nxtbook.com/farran/dentaltown/dentaltown-july-2021
https://www.nxtbook.com/farran/dentaltown/dentaltown-june-2021
https://www.nxtbook.com/farran/dentaltown/dentaltown-may-2021
https://www.nxtbook.com/farran/dentaltown/dentaltown-april-2021
https://www.nxtbook.com/farran/dentaltown/dentaltown-march-2021
https://www.nxtbook.com/farran/dentaltown/dentaltown-february-2021
https://www.nxtbook.com/farran/dentaltown/2021January
https://www.nxtbook.com/farran/dentaltown/2020December
https://www.nxtbook.com/farran/dentaltown/2020November
https://www.nxtbook.com/farran/dentaltown/2020NewGrad
https://www.nxtbook.com/farran/dentaltown/2020October
https://www.nxtbook.com/farran/dentaltown/2020September
https://www.nxtbook.com/farran/dentaltown/2020August
https://www.nxtbook.com/farran/dentaltown/2020July
https://www.nxtbook.com/farran/dentaltown/2020June
https://www.nxtbook.com/farran/dentaltown/2020May
https://www.nxtbook.com/farran/dentaltown/2020April
https://www.nxtbook.com/farran/dentaltown/2020March
https://www.nxtbook.com/farran/dentaltown/2020February
https://www.nxtbook.com/farran/dentaltown/2020January
https://www.nxtbook.com/farran/dentaltown/2019December
https://www.nxtbook.com/farran/dentaltown/2019November
https://www.nxtbook.com/farran/dentaltownuk/2019OctoberNovember
https://www.nxtbook.com/farran/dentaltown/2019October
https://www.nxtbook.com/farran/dentaltown/2019NewGrad
https://www.nxtbook.com/farran/dentaltown/2019September
https://www.nxtbook.com/farran/dentaltown/2019August
https://www.nxtbook.com/farran/dentaltown/2019July
https://www.nxtbook.com/farran/dentaltownuk/2019JuneJuly
https://www.nxtbook.com/farran/dentaltown/2019June
https://www.nxtbook.com/farran/dentaltown/2019May
https://www.nxtbook.com/farran/dentaltownuk/2019AprilMay
https://www.nxtbook.com/farran/dentaltown/2019April
https://www.nxtbook.com/farran/dentaltown/2019March
https://www.nxtbook.com/farran/dentaltown/2019February
https://www.nxtbook.com/farran/dentaltownuk/2019FebruaryMarch
https://www.nxtbook.com/farran/dentaltown/2019January
https://www.nxtbook.com/farran/dentaltownuk/2018Winter
https://www.nxtbook.com/farran/dentaltown/2018December
https://www.nxtbook.com/farran/dentaltown/2018November
https://www.nxtbook.com/farran/dentaltownuk/2018November
https://www.nxtbook.com/farran/dentaltown/2018October
https://www.nxtbook.com/farran/dentaltownuk/2018October
https://www.nxtbook.com/farran/dentaltown/2018NewGrad
https://www.nxtbook.com/farran/dentaltown/2018September
https://www.nxtbook.com/farran/dentaltownuk/2018September
https://www.nxtbook.com/farran/dentaltown/2018August
https://www.nxtbook.com/farran/dentaltownuk/2018July
https://www.nxtbook.com/farran/dentaltown/2018July
https://www.nxtbook.com/farran/dentaltownuk/2018June
https://www.nxtbook.com/farran/dentaltown/2018June
https://www.nxtbook.com/farran/dentaltownuk/2018May
https://www.nxtbook.com/farran/dentaltown/2018May
https://www.nxtbook.com/farran/dentaltownuk/2018April
https://www.nxtbook.com/farran/dentaltown/2018April
https://www.nxtbook.com/farran/dentaltown/2018March
https://www.nxtbook.com/farran/dentaltownuk/2018March
https://www.nxtbook.com/farran/dentaltown/2018February
https://www.nxtbook.com/farran/dentaltownuk/2018February
https://www.nxtbook.com/farran/dentaltown/2018January
https://www.nxtbook.com/farran/dentaltown/2017December
https://www.nxtbook.com/farran/dentaltownuk/2017Winter
https://www.nxtbook.com/farran/dentaltown/2017November
https://www.nxtbook.com/farran/dentaltown/2017October
https://www.nxtbook.com/farran/dentaltownuk/2017october
https://www.nxtbook.com/farran/dentaltown/NewGrad2017
https://www.nxtbook.com/farran/dentaltown/2017September
https://www.nxtbook.com/farran/dentaltownuk/2017September
https://www.nxtbook.com/farran/dentaltownuk/2017August
https://www.nxtbook.com/farran/dentaltown/2017August
https://www.nxtbook.com/farran/dentaltown/2017July
https://www.nxtbook.com/farran/dentaltownuk/2017July
https://www.nxtbook.com/farran/dentaltown/2017June
https://www.nxtbook.com/farran/dentaltownuk/2017may
https://www.nxtbook.com/farran/dentaltown/2017May
https://www.nxtbook.com/farran/dentaltownuk/2017April
https://www.nxtbook.com/farran/dentaltown/2017April
https://www.nxtbook.com/farran/dentaltown/2017March
https://www.nxtbook.com/farran/dentaltownuk/dentaltownuk/2017march
https://www.nxtbook.com/farran/dentaltown/February2017
https://www.nxtbook.com/farran/dentaltown/2017January
https://www.nxtbook.com/farran/dentaltown/2016December
https://www.nxtbook.com/farran/dentaltown/2016November
https://www.nxtbook.com/farran/dentaltown/2016October
https://www.nxtbook.com/farran/dentaltown/2016nge
https://www.nxtbook.com/farran/dentaltown/2016september
https://www.nxtbook.com/farran/dentaltown/2016august
https://www.nxtbook.com/farran/dentaltown/2016july
https://www.nxtbook.com/farran/dentaltown/2016june
https://www.nxtbook.com/farran/dentaltown/2016may
https://www.nxtbook.com/farran/dentaltown/2016april
https://www.nxtbook.com/farran/dentaltown/2016march
https://www.nxtbook.com/farran/dentaltown/2016february
https://www.nxtbook.com/farran/dentaltown/2016january
https://www.nxtbook.com/farran/dentaltown/2015december
https://www.nxtbook.com/farran/dentaltown/2015november
https://www.nxtbook.com/farran/dentaltown/2015october
https://www.nxtbook.com/farran/dentaltown/2015nge
https://www.nxtbook.com/farran/dentaltown/2015september
https://www.nxtbook.com/farran/dentaltown/2015august
https://www.nxtbook.com/farran/dentaltown/2015july
https://www.nxtbook.com/farran/dentaltown/2015june
https://www.nxtbook.com/farran/dentaltown/2015may
https://www.nxtbook.com/farran/dentaltown/2015april
https://www.nxtbook.com/farran/dentaltown/2015march
https://www.nxtbook.com/farran/dentaltown/2015february
https://www.nxtbook.com/farran/dentaltown/2015january
https://www.nxtbook.com/farran/dentaltown/2014december
https://www.nxtbook.com/farran/dentaltown/2014decemberb
https://www.nxtbook.com/farran/dentaltown/2014november
https://www.nxtbook.com/farran/dentaltown/2014october
https://www.nxtbook.com/farran/dentaltown/2014newgrad
https://www.nxtbook.com/farran/dentaltown/2014september
https://www.nxtbook.com/farran/dentaltown/2014august
https://www.nxtbook.com/farran/dentaltown/2014july
https://www.nxtbook.com/farran/dentaltown/2014june
https://www.nxtbook.com/farran/dentaltown/2014may
https://www.nxtbook.com/farran/dentaltown/2014april
https://www.nxtbook.com/farran/dentaltown/2014march
https://www.nxtbook.com/farran/dentaltown/2014february
https://www.nxtbook.com/farran/dentaltown/2014january
https://www.nxtbook.com/farran/dentaltown/2013december
https://www.nxtbook.com/farran/dentaltown/2013november
https://www.nxtbook.com/farran/dentaltown/2013october
https://www.nxtbook.com/farran/dentaltown/2013newgrad
https://www.nxtbook.com/farran/dentaltown/2013september
https://www.nxtbook.com/farran/dentaltown/2013august
https://www.nxtbook.com/farran/dentaltown/2013july
https://www.nxtbook.com/farran/dentaltown/2013june
https://www.nxtbook.com/farran/dentaltown/2013may
https://www.nxtbook.com/farran/dentaltown/2013april
https://www.nxtbook.com/farran/dentaltown/2013march
https://www.nxtbook.com/farran/dentaltown/2013february
https://www.nxtbook.com/farran/dentaltown/2013january
https://www.nxtbook.com/farran/dentaltown/2012december
https://www.nxtbook.com/farran/dentaltown/2012November
https://www.nxtbookmedia.com