Dentaltown April 2018 - 89

Disrupting Biofilm:
Beyond Antibiotics
Hydrogen peroxide treatment demonstrates decrease in bacterial infections

by Milton Marshall, PhD, DABT, and
Tanya Dunlap, PhD
Toxicologist and biochemist
Milton Marshall, PhD, DABT,
researched safety data on the
use of hydrogen peroxide in
dentistry, which was presented
to the FDA and ADA. He has
also worked to examine the
biocompatibility and safety of
dental materials.
Tanya Dunlap, PhD, is the managing
director for Perio Protect, where
she has worked since 2005. She
coordinates clinical research
involving prescription tray delivery.
She also offers CE courses on
the science behind prescription
tray delivery and the important
implications of the research data.

88

APRIL 2018 // dentaltown.com

A

ntibiotics are a staple in dental offices to counter bacterial
infections. For the treatment of
periodontal disease, antibiotics
have been widely used to fight
gingival infections and the resulting inflammatory responses, and the antibiotics can
help. Efficacy is often short-lived, however,
because periodontitis is a biofilm-based
disease that, like other biofilm infections,
is refractory to antibiotics.1 Nevertheless,
the underlying problem is inflammation
prompted from a bacterial infection, and
we are taught that antibiotics are the right
course. When they don't work well or when
the results are not long-lasting, we often
think that we just need the right antibiotic.

But what if antibiotics aren't the best option?
Paradigms that shape our views are
often so ingrained that we don't realize how
they frame our thoughts-or our treatment
approaches. It's time to challenge the antibiotic treatment default for periodontal
therapy. This means not that antibiotics
shouldn't be used but that they need to be
used more judiciously.2
The underlying premise of the challenge:
If our current mechanical, surgical and
antibiotic treatments worked well, then
47 percent of American adults would not
have chronic periodontitis. But they do,
and millions more have gingivitis.3 We
want to find fault with patients, and home
care is a clear fault line where most patients


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Table of Contents for the Digital Edition of Dentaltown April 2018

Dentaltown April 2018 - Intro
Dentaltown April 2018 - Cover1
Dentaltown April 2018 - Cover2
Dentaltown April 2018 - 1
Dentaltown April 2018 - 2
Dentaltown April 2018 - 3
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Dentaltown April 2018 - Cover3
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