Drug Topics- August 11, 2008

58 DRUG TOPICS AUGUST 11, 2008 www.drugtopics.com TEST QUESTIONS 3. Treatment should be started within in order 12. What percentage of children has resolution of their to reduce pharyngitis symptoms due to Group A streptococcus? a. 12 hours b. 24 hours c. 48 hours d. 72 hours otitis media symptoms within seven to 14 days without antibiotic treatment? a. 10%-20% b. 25%-30% c. 40%-50% d. 70%-90% 4. The first-line treatment for Group A streptococcus is 13. A mother of a four-month-old baby needs antibiotics which of the following? a. Penicillin V 250mg BID for 10 days b. Penicillin V 500mg BID for 10 days c. Penicillin V 500mg TID for 5 days d. Penicillin V 500mg QID for 5 days for her child’s first ear infection. Which of the following treatment regimens would be a first-line option within the first 24 hours? a. “Wait and see” for 48-72 hours b. Amoxicillin 80-90mg/kg c. Clarithromycin 15mg/kg d. Clindamycin 30-40mg/kg 5. What percentage of bacterial sinusitis infections re- solves without antibiotics? a. 10% b. 25% c. 50% d. 75% 14. The mother comes back later with her seven-year- old son with the same diagnosis of otitis media. He is penicillin-allergic (rash). What is your treatment recommendation? a. “Wait and see” for 48-72 hours b. Amoxicillin 80-90mg/kg c. Clarithromycin 15mg/kg d. Clindamycin 30-40mg/kg 6. When antibiotic treatment for sinusitis is prescribed, what is the duration of therapy? a. Five to seven days b. Seven to 10 days c. 10-14 days d. 14-21 days 15. True or False? Topical corticosteroids assist in pro- 7. Which pathogen is responsible for the majority of the viding symptomatic relief of ear effusions and offer long-term benefits. a. True b. False dry, wheezy “high-pitched” coughs? a. Respiratory syncytial virus (RSV) b. Streptococcus pneumoniae c. Human metapneumonvirus d. Influenza virus 16. When reviewing the CURB-65 score, what is the respiratory rate cutoff that is used to calculate an additional risk factor? a. > 20 breaths/min b. > 25 breaths/min c. > 30 breaths/min d. > 65 breaths/min 8. What is Ribavirin’s pregnancy category? a. B b. C c. D d. X 9. Which of the following organisms is least likely to be 17. Your interview with a 50-year-old patient with sus- identified in an upper respiratory tract infection? a. Pseudomonas aeruginosa b. Streptococcus pneumoniae c. Moraxella catarrhalis d. Haemophilis influenzae pected CAP provides no indication of confusion. He has a respiratory rate of 25 breaths, a BUN of 5mmol/L, and blood pressure of 87/65 mmHg. What is your assessment of his CURB-65 score and treatment option? a. His score is zero, he may be treated as an outpatient b. His score is one, he may be treated as an outpatient c. His score is two, he may be treated as an outpatient d. His score is three, he should be admitted for inpatient treatment 10. A patient presents to your pharmacy complaining of a cough with a whooping sound along with nausea and vomiting. What is the most likely pathogen? a. Streptococcus pneumoniae b. Bordetella pertussis c. Respiratory syncytial virus (RSV) d. Adenovirus 18. Thomas is a 65-year-old smoker with diabetes who 11. Which of the following antibiotic therapies would NOT be a good choice for a diagnosis of acute exacerbations of chronic bronchitis (AECB)? a. Penicillin V 500mg BID b. Augmentin 875mg BID c. Moxifloxacin 400mg daily d. Azithromycin (Z-pack) was recently diagnosed with COPD. What treatment option would you recommend for his communityacquired pneumonia? a. Ciprofloxacin 500mg BID b. Levofloxacin 500mg daily c. Levofloxacin 750mg daily d. Clarithromycin 500mg BID http://www.drugtopics.com

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Drug Topics- August 11, 2008 Contents Latebreakers Letters DEA Proposes Rule To Allow Electronic Prescriptions for Controlled Substances Merger, Medicare Reform Could Mean Broader E-Prescribing Adoption New Combination Pill Approved for Type 2 Diabetes New Eczema Guildlines Promote Use of Emollients, Then Topical Corticosteroids Agencies Flush Original Strategies in Favor of Promoting Drug Take-Back Programs JP at Large: You Laughing at Me? Pharmacists Find Themselves at Mercy of Prior Authorization State Law Requiring PBM Transparency See Some Gains, Some Losses Global Counterfeiting Still Growing, Says U.S. Commerce Official FDA Saftey Page: Prophylthiouracil Still Confused with Purinethol (mercaptopurine) New Products Bring Lice Treatment to a Head NACDS Marketplace Showcases New Product that Fill Unmet Needs Update on Respiratory Tract Infections Execs Share War Stories About Adopting Technology in their Stores New Products Advertisters Index Classified Viewpoint: Medicare Part D Revisions sorely needed

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