LCGC The Peak - April 2008 - (Page 13) APRIL 2008 THE PEAK 13 1.3 1.21 10 2 Time SEC (min) 1.1 11 12 3 1 4 0.9 6 7 8 9 13 14 5 0.8 0.5 1 1.5 2 Time LC (h) 2.5 3 3.5 4 Figure 4: Structured two-dimensional chromatogram obtained for the separation of random copolymers by LC SEC. Detector, evaporative light scattering; analyte polymers, PMMA Mp 2,900 (1), 6,950 (2), 28,300 (3), 127,000 (4), 840,000 (5), S-co-MMA 20% S (6) Sample Dimensionality: Structured Chromatograms Although we mortals are in no position to dictate the exact positioning of all peaks in very complex two-dimensional chromatograms, we do have significant possibilities to set the separations to our hands. The concept of sample dimensionality (14) is extremely useful in this context. A dimension of a sample can be seen as a property that sets the molecules apart from each other. For example, in a homologous series, the number of methylene groups would be the unique feature differentiating between molecules, and a solution of n-alkanes can be seen as a onedimensional sample. In tryglycerides, the number of unsaturations might be another dimension. However, to uniquely define a molecule the position of the double bond is relevant also, so that a sample of triglycerides can be more than two-dimensional. If we manage to align the most important dimensions of the sample with the separation mechanisms, we can obtain structured separations.
Table of Contents Feed for the Digital Edition of LCGC The Peak - April 2008 LCGC The Peak - April 2008 Contents LC3LC: Comprehensive Two-Dimensional Liquid Chromatography Split Injections in Gas Chromatography: How to Reduce Inlet Discrimination A Simple and Solvent-Free Method for Determining Tetracyclines in Prawns Industry News Events Education LCGC The Peak - April 2008 LCGC The Peak - April 2008 - LCGC The Peak - April 2008 (Page 1) LCGC The Peak - April 2008 - LCGC The Peak - April 2008 (Page 2) LCGC The Peak - April 2008 - LCGC The Peak - April 2008 (Page 3) LCGC The Peak - April 2008 - Contents (Page 4) LCGC The Peak - April 2008 - Contents (Page 5) LCGC The Peak - April 2008 - Contents (Page 6) LCGC The Peak - April 2008 - LC3LC: Comprehensive Two-Dimensional Liquid Chromatography (Page 7) LCGC The Peak - April 2008 - LC3LC: Comprehensive Two-Dimensional Liquid Chromatography (Page 8) LCGC The Peak - April 2008 - LC3LC: Comprehensive Two-Dimensional Liquid Chromatography (Page 9) LCGC The Peak - April 2008 - LC3LC: Comprehensive Two-Dimensional Liquid Chromatography (Page 10) LCGC The Peak - April 2008 - LC3LC: Comprehensive Two-Dimensional Liquid Chromatography (Page 11) LCGC The Peak - April 2008 - LC3LC: Comprehensive Two-Dimensional Liquid Chromatography (Page 12) LCGC The Peak - April 2008 - LC3LC: Comprehensive Two-Dimensional Liquid Chromatography (Page 13) LCGC The Peak - April 2008 - LC3LC: Comprehensive Two-Dimensional Liquid Chromatography (Page 14) LCGC The Peak - April 2008 - LC3LC: Comprehensive Two-Dimensional Liquid Chromatography (Page 15) LCGC The Peak - April 2008 - Split Injections in Gas Chromatography: How to Reduce Inlet Discrimination (Page 16) LCGC The Peak - April 2008 - Split Injections in Gas Chromatography: How to Reduce Inlet Discrimination (Page 17) LCGC The Peak - April 2008 - Split Injections in Gas Chromatography: How to Reduce Inlet Discrimination (Page 18) LCGC The Peak - April 2008 - Split Injections in Gas Chromatography: How to Reduce Inlet Discrimination (Page 19) LCGC The Peak - April 2008 - A Simple and Solvent-Free Method for Determining Tetracyclines in Prawns (Page 20) LCGC The Peak - April 2008 - A Simple and Solvent-Free Method for Determining Tetracyclines in Prawns (Page 21) LCGC The Peak - April 2008 - A Simple and Solvent-Free Method for Determining Tetracyclines in Prawns (Page 22) LCGC The Peak - April 2008 - A Simple and Solvent-Free Method for Determining Tetracyclines in Prawns (Page 23) LCGC The Peak - April 2008 - A Simple and Solvent-Free Method for Determining Tetracyclines in Prawns (Page 24) LCGC The Peak - April 2008 - A Simple and Solvent-Free Method for Determining Tetracyclines in Prawns (Page 25) LCGC The Peak - April 2008 - A Simple and Solvent-Free Method for Determining Tetracyclines in Prawns (Page 26) LCGC The Peak - April 2008 - Industry News (Page 27) LCGC The Peak - April 2008 - Events (Page 28) LCGC The Peak - April 2008 - Events (Page 29) LCGC The Peak - April 2008 - Education (Page 30) LCGC The Peak - April 2008 - Education (Page 31) LCGC The Peak - April 2008 - Education (Page 32)
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