Patient Care - Allergy & Immunology - October 2007 - (Page 18)

I Medicine in the News Continued from page 5 I Angioedema expert panel and published a consensus stateIn the ED, ment providing guidpatient ance for the emergency education is physician managing an given great anaphylactic episode.1 prominence, The consensus statement reiterates that as summed “prompt administration up in the of epinephrine is widemnemonic ly accepted as first-line device SAFE. therapy for . . . an anaphylactic episode” and refers ED personnel to publications of the National Institute of Allergy and Infectious Diseases and the ACAAI for guidance on optimal treatment. In the ED, patient education is given great prominence, as summed up in the mnemonic device SAFE (page 5). 1. Lieberman P, Decker W, Camargo CA Jr, et al. SAFE: a multidisciplinary approach to anaphylaxis education in the emergency department. Ann Allergy Asthma Immunol. 2007;98(6):519-523. WRITTEN BY JUDITH ASCH-GOODKIN 2. Osler W. Hereditary angioneurotic oedema. Am J Med Sci. 1988;95: 362-367. 3. Donaldson VH, Evans RR. A biochemical abnormality in hereditary angioneurotic edema: absence of serum inhibitor of C1-esterase. Am J Med. 1963;35:37-44. 4. Kostis JB, Packer M, Black HR, et al. Omapatrilat and enalapril in patients with hypertension: the Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) trial. Am J Hypertens. 2004;17(2):103-111. 5. Kaplan AP. Angioedema. J Am Acad Dermatol. 2005;53(3):373-388. 6. Nzeako UC, Frigas E, Tremaine WJ. Hereditary angioedema: a broad review for clinicians. Arch Intern Med. 2001;161:2419-2423. 7. Bork K, Hardt J, Schicketanz KH, et al. Clinical studies of sudden upper airway obstruction in patients with hereditary angioedema due to C1 esterase inhibitor deficiency. Arch Intern Med. 2003;163:1229-1235. 8. Farkas H, Varga L, et al. Management of hereditary angioedema in pediatric patients. Pediatrics. 2007;120:e713-e722. 9. Kostis JB, Kim HJ, Rusnak J, et al. Incidence and characteristics of angioedema associated with enalapril. Arch Intern Med. 2005; 165(14):1637-1642. 10. Agostoni A, Cicardi M, Cugno M, et al. Angioedema due to angiotensinconverting enzyme inhibitors. Immunopharmacology. 1999;44(1–2): 21-25. 11. Johnsen SP, Jacobsen J, Monster TB, et al. Risk of first-time hospitalization for angioedema among users of ACE inhibitors and angiotensin receptor antagonists. Am J Med. 2005;118(12):1428-1429. 12. Palmer M, Rosenbaum S. Clinical Practice Guideline of the American Academy of Emergency Medicine (AAEM): initial evaluation and management of patients presenting with acute urticaria or angioedema. http://www.aaem.org/positionstatements/clinical_practice_guidelines. php. Accessed October 1, 2007. 13. Sampson HA, Munoz-Furlong, A, Campbell RL, et al. Second symposium on the definition and management of anaphylaxis: summary report—second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. Ann Emerg Med. 2006;47(4):373-380. 14. Thomas M, Crawford I. Best evidence topic report: glucagon infusion in refractory anaphylactic shock in patients on beta-blockers. Emerg Med J. 2005;22:272-273. 15. Kemp SF, Lockey RF. Anaphylaxis: a review of causes and mechanisms. J Allerg Clin Immunol. 2002;110(3):341-348. 16. McLean-Tooke AP, Bethune CA, Fay AC, et al. Adrenaline in the treatment of anaphylaxis: what is the evidence? BMJ. 2003;327(7427): 1332-1335. 17. Lin RY, Curry A, Pesola GR, et al. Improved outcomes in patients with acute allergic syndromes who are treated with combined H1 and H2 antagonists. Ann Emerg Med. 2000;36(5):462-468. 18. Sicherer SH, Simons FE. Quandaries in prescribing an emergency action plan and self-injectable epinephrine for first-aid management of anaphylaxis in the community. J Allergy Clin Immunol. 2005;115(3):575583. 19. Lee JM, Greenes DS. Biphasic anaphylactic reactions in pediatrics. Pediatrics. 2000;10(4):762-766. 20. Orson FM. Intravenous immunoglobulin therapy suppresses manifestations of the angioedema with hypereosinophilia syndrome. Am J Med Sci. 2003;326(2):94-97. www.patientcareonline.com Visit our Web site for ® Click-through links to the Internet resources listed in these pages 18 PATIENT CARE ALLERGY & IMMUNOLOGY www.patientcareonline.com http://www.aaem.org/positionstatements/clinical_practice_guidelines.php http://www.aaem.org/positionstatements/clinical_practice_guidelines.php http://www.patientcareonline.com http://www.patientcareonline.com

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Patient Care - Allergy & Immunology - October 2007 Research Digest Contents Medicine in the News When to Suspect Celiac Disease and How to Proceed From There Averting Angioedema’s Potentially Dire Consequences Is There a Role for Leukotriene Receptor Antagonists in Treating Allergic rhinitis? Clinical Clips Dermatology Case Challenge Classified Advertising

Patient Care - Allergy & Immunology - October 2007

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