Patient Care Endocrinology & Cardiology - October 2007 - (Page 20)

Accreditation This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of CME2, Inc. (“cme2”) and Patient Care. cme2 is accredited by the ACCME to provide continuing medical education for physicians. cme2 designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity. Target audience: Primary care physicians CME Credit: Earn AMA PRA Category 1 Credit™ Educational objectives After reading this material, physicians should be able to • Summarize the role of cardiac troponins (cTns) in patients with acute coronary syndromes (ACS), MI, and other illnesses, and explain the significance of detectable/increased levels of cTn. • Recognize the advantages and disadvantages of new assays for cTn. • Recognize the degree of cTn elevation required to distinguish cardiac from non-ACS causes. • Identify the specific conditions associated with cTn elevation and summarize the guidelines for consulting with the cardiology service. Using troponins to evaluate cardiac injury Cardiac troponin levels can have important prognostic implications and often guide the course of treatment in patients with acute coronary syndromes, MI, and other illnesses. Learn how to best use these important tests in clinical practice. To earn CME credit for this activity Participants should study the article, log on to ModernMedicine.com on the “CME/CE Center” tab at the top of the page, and type in keyword PC102007. Participants will be taken to the activity where they must pass a post-test and complete an online evaluation. After passing the post-test and completing the online evaluation, a CME certificate will be automatically generated. The release date for this activity is October 1, 2007. The expiration date is October 1, 2008. Resolution of conflict of interest cme2 has implemented a process to resolve conflicts of interest for each continuing medical education activity, to help ensure content validity, independence, fair balance, and that the content is aligned with the interest of the public. Conflicts, if any, are resolved through a peer review process. T Unapproved/off-label use discussion Faculty members may discuss information about pharmaceutical agents, devices, or diagnostic products that are outside of FDAapproved labeling. This information is intended solely for CME and is not intended to promote off-label use of these medications. If you have questions, contact the medical affairs department of the manufacturer for the most recent prescribing information. The faculty is required to disclose any off-label discussion. he troponins are constitutive proteins involved in the regulation and mediation of cardiac contraction. As with many structural and enzymatic proteins in the myocardium, troponins—or their metabolites—are released into the vascular space in the presence of myocardial necrosis. Although all muscle fibers contain troponin, the isoforms of troponins I and T present in cardiac muscle are distinct from the skeletal muscle forms. As a result, measurement of these cardiac troponins is specific to cardiac injury. When troponin is mentioned in this review, the cardiac form (cTn) is implied. Three distinct forms of troponin make up the troponin complex: troponin I, T, and C (see Figure 1). CONTRIBUTOR Editors Peter D’Epiro, Karen Clemments, Mary Desmond Pinkowish, instructional design consultant Richard Currier, and the manuscript editors disclose that they do not have any financial relationship with any manufacturer in this area of medicine. One of the article reviewers discloses that he is a consultant for Bristol-Myers Squibb (BMS) and Pfizer and a member of the speakers’ bureau for BMS, Sanofi, Pfizer, and GlaxoSmithKline. MATTHEW DECARO, MD, Director, Coronary Care Unit, Thomas Jefferson University Hospital, Philadelphia, Pa. Dr DeCaro discloses that he does not have any financial relationship with any manufacturer in this area of medicine. 20 PATIENT CARE ENDOCRINOLOGY & CARDIOLOGY www.patientcareonline.com http://ModernMedicine.com http://www.patientcareonline.com

Table of Contents Feed for the Digital Edition of Patient Care Endocrinology & Cardiology - October 2007

Patient Care - Endocrinology & Cardiology - October 2007 Research Digest Contents Medicine in the News Recognizing and Managing Patients with the Metabolic Syndrome and Prediabetes Using Troponins to Evaluate Cardiac Injury The 15-Minute Visit Classified Advertising Clinical Clips

Patient Care Endocrinology & Cardiology - October 2007

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