Veterinary Medicine - February 2008 - (Page MV15) Jergens: If we move toward early feeding, then I think we need to be more aggressive with antiemetics, not only so the patient will eat on its own but also to reduce the potential for aspiration after vomiting. Williams: I wonder if we are overemphasizing the risk of administering symptomatic, antiemetic and antinausea therapy. Earlier we discussed being concerned about masking the signs of an obstructive lesion, but if your workup is appropriate, then you probably would detect it. Maybe we risk denying a positive e ect in many of our patients because we are overly concerned about masking signs in a small minority. Twedt: Some cases will be missed. We just have to do our best to rule out obstructive disease or foreign bodies. Certainly you don’t want to treat a dog that has Addison’s disease with an antiemetic. You treat the Addison’s disease. Williams: We are much more aggressive at treating perceived pain now, and we should be more aggressive at treating perceived nausea as well. Our patients may do better as a result. Simpson: So we look for hypersalivation, restlessness, and food aversion, rather than emesis. It is a prodromal sign. Lieb: In conclusion, maropitant is making life easier for practitioners— and better for their patients. Benchaoui H, et al. The anti-emetic efcacy of maropitant (Cerenia) in the treatment of ongoing emesis caused by a wide range of underlying clinical aetiologies in canine patients in Europe. J Small Anim Pract 2007:48:93-98. 4. Vail D, Rodabaugh H, Conder G, et al. Ef cacy of injectable maropitant (Cerenia) in a randomized clinical trial for prevention and treatment of cisplatin-induced emesis in dogs presented as veterinary patients. Vet Comp Oncol 2007;5:38-46. 5. de la Puente-Redondo V, Tilt N, Rowan TG, et al. Ef cacy of maropitant for treatment and prevention of emesis caused by intravenous infusion of cisplatin in dogs. Am J Vet Res 2007;68:48-56. 6. Mohr AJ, Leisewitz AL, Jacobson LS, et al. Effect of early enteral nutrition on intestinal permeability, intestinal protein loss, and outcome in dogs with severe parvoviral enteritis. J Vet Intern Med 2003;17:791-798. 7. Chan DL, Freeman LM, Labato MA, et al. Retrospective evaluation of partial parenteral nutrition in dogs and cats. J Vet Intern Med 2002;16:440-445. References 1. Hume DZ, Drobatz KJ, Hess RS. Outcome of dogs with diabetic ketoacidosis: 127 dogs. J Vet Intern Med 2006;20:547-55. 2. Cerenia (maropitant citrate) tablets. P zer Animal Health, New York, NY. Product label, Nov 2006. 3. de la Puente-Redondo V, Siedek E, 15
For optimal viewing of this digital publication, please enable JavaScript and then refresh the page. If you would like to try to load the digital publication without using Flash Player detection, please click here.