Veterinary Medicine - March 2008 - (Page 169)

39. Nemanic S, London CA, Wisner ER. Comparison of thoracic radiographs and single breath-hold helical CT for detection of pulmonary nodules in dogs with metastatic neoplasia. J Vet Intern Med 2006;20(3):508-515. 40. Castellano MC, Massone AR, Idiart JR. Primary pulmonary adenocarcinoma metastatic to the uvea, brain and adrenal gland in a dog. J Vet Med A Physiol Pathol Clin Med 2006;53(4):194-197. 41. Ibarrola P, German AJ, Stell AJ, et al. Appendicular arterial tumor embolization in two cats with pulmonary carcinoma. J Am Vet Med Assoc 2004;225(7):1065-1069, 1048-1049. 42. van der Linde-Sipman JS, van den Ingh TS. Primary and metastatic carcinomas in the digits of cats. Vet Q 2000;22(3):141-145. 43. Bertazzolo W, Zuliani D, Pogliani E, et al. Diffuse bronchioloalveolar carcinoma in a dog. J Small Anim Pract 2002;43(6):265-268. 44. Sharkey LC, Rosol TJ, Grone A, et al. Production of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor by carcinomas in a dog and a cat with paraneoplastic leukocytosis. J Vet Intern Med 1996;10(6):405-408. 45. Anderson TE, Legendre AM, McEntee MM. Probable hypercalcemia of malignancy in a cat with bronchogenic adenocarcinoma. J Am Anim Hosp Assoc 2000;36(1):52-55. 46. Dole RS, MacPhail CM, Lappin MR. Paraneoplastic leukocytosis with mature neutrophilia in a cat with pulmonary squamous cell carcinoma. J Feline Med Surg 2004;6(6):391-395. 47. Hogan DF, Dhaliwal RS, Sisson DD, et al. Paraneoplastic thrombocytosis-induced systemic thromboembolism in a cat. J Am Anim Hosp Assoc 1999;35(6):483-486. 48. Lansdowne JL, Monnet E, Twedt DC, et al. Thoracoscopic lung lobectomy for treatment of lung tumors in dogs. Vet Surg 2005;34(5):530-535. 49. Lin J, Iannettoni MD. The role of thoracoscopy in the management of lung cancer. Surg Oncol 2003;12(3):195-200. 50. Poirier VJ, Burgess KE, Adams WM, et al. Toxicity, dosage, and ef cacy of vinorelbine (Navelbine) in dogs with spontaneous neoplasia. J Vet Intern Med 2004;18(4):536-539. 51. Krikorian A, Rahmani R, Bromet M, et al. Pharmacokinetics and metabolism of Navelbine. Semin Oncol 1989;16(2 suppl 4):21-25. 52. Ballegeer EA, Forrest LJ, Jeraj R, et al. PET/CT following intensity-modulated radiation therapy for primary lung tumor in a dog. Vet Radiol Ultrasound 2006;47(2):228-233. 53. Ahrar K, Price RE, Wallace MJ, et al. Percutaneous radiofrequency ablation of lung tumors in a large animal model. J Vasc Interv Radiol 2003;14(8):1037-1043. 54. Moore AS, Kirk C, Cardona A. Intracavitary cisplatin chemotherapy experience with six dogs. J Vet Intern Med 1991;5(4):227-231. 55. Charney SC, Bergman PJ, McKnight JA, et al. Evaluation of intracavitary mitoxantrone and carboplatin for treatment of carcinomatosis, sarcomatosis, and mesothelioma, with or without malignant effusions: a retrospective analysis of 12 cases (1997-2002). Vet Comp Oncol 2005;3:171-181. 56. Hershey AE, Kurzman ID, Forrest LJ, et al. Inhalation chemotherapy for macroscopic primary or metastatic lung tumors: proof of principle using dogs with spontaneously occurring tumors as a model. Clin Cancer Res 1999;5(9):2653-2659. 57. Khanna C, Vail DM. Targeting the lung: preclinical and comparative evaluation of anticancer aerosols in dogs with naturally occurring cancers. Curr Cancer Drug Targets 2003;3(4):265-273. 58. Dorn CR, Taylor DO, Frye FL, et al. Survey of animal neoplasms in Alameda and Contra Costa Counties, California. I. Methodology and description of cases. J Natl Cancer Inst 1968;40(2):295-305. 59. Theilen GH, Madewell BR. Tumors of the respiratory tract and thorax. In: Theilen GH, Madewell BR, eds. Veterinary cancer medicine. Philadelphia, Pa: Lea and Febiger, 1979;341-346. 60. Clements DN, Hogan AM, Cave TA. Treatment of a well differentiated pulmonary adenocarcinoma in a cat by pneumonectomy and adjuvant mitoxantrone chemotherapy. J Feline Med Surg 2004;6(3):199-205. CE You can earn two hours of Continuing Education credit from Kansas State University by answering the following questions on primary lung cancer. Circle only the best answer for each question, and transfer your answers to the form on page 170 or take the test online at https://www.dce.ksu.edu/ce/vetmed/. This test expires April 1, 2009. Article #1 1. The one canine breed that may have a predisposition to primary pulmonary neoplasia is: a. German shepherds b. Golden retrievers c. Boxers d. Labrador retrievers e. Standard poodles 6. Which factor was found to affect prognosis in patients with primary lung tumors? a. Age b. Sex c. Histologic score d. Weight e. Breed 2. The most commonly diagnosed primary tumor of the lung is: a. Sarcoma b. Carcinoma c. Round cell tumors d. Benign neoplasms e. Neuroendocrine tumors 7. Although rare, the most common paraneoplastic syndrome in dogs with primary lung tumors is: a. Fever b. ACTH secretion c. Hypertrophic osteopathy d. Hypercalcemia e. Thromboembolism 3. The most common presenting clinical sign in dogs with primary lung tumors is: a. Dyspnea b. Vomiting c. Nonproductive cough d. Lethargy e. Fever 8. The single best treatment for solitary primary pulmonary neoplasia is: a. Complete surgical excision b. Intravenous vinorelbine chemotherapy c. Intravenous mitoxantrone chemotherapy d. IMRT e. Inhaled cytokines 4. If you were to cytologically determine that the mass on your feline patient’s digit was epithelial in origin, your top differential diagnosis would be: a. Primary digital carcinoma b. Metastatic pulmonary carcinoma c. Metastatic hepatic carcinoma d. Metastatic pulmonary sarcoma e. None of the above 9. The major beneﬁt of using IMRT to irradiate a primary lung tumor is: a. Faster results b. Less radiation to the patient c. Sparing normal tissue d. More cost-effective e. None of the above 5. According to the WHO staging classiﬁcation scheme, the single best prognostic indicator for primary lung tumors is: a. Lymph node involvement b. Primary tumor size c. Distant site metastasis d. The central location of the tumor e. The peripheral location of the tumor 10. Which inhalation therapy has demonstrated effectiveness in treating dogs with primary or metastatic lung cancer? a. Mitoxantrone b. Gemcitabine c. Cyclophosphamide d. Doxorubicin e. Both A and D EXTRAS See for information on thoracic radiography in cats and dogs. VETERINARY MEDICINE March 2008 169 https://www.dce.ksu.edu/ce/vetmed/ http://www.vetstreamcanis.com/ACI/March08/VMD2/teq00642.asp http://www.vetstreamfelis.com/ACI/March08/VMD1/teq00642.asp

Table of Contents Feed for the Digital Edition of Veterinary Medicine - March 2008

Veterinary Medicine - March 2008 Contents Toxicology Brief Idea Exchange A Challenging Case An Update on Diagnosing and Treating Primary Lung Tumors CE Form Product Preview Advertiser Index Marketplace/Classifieds Mind Over Miller

Veterinary Medicine - March 2008

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