Veterinary Medicine - April 2008 - (Page 222)

Canine anaplasmosis PEER-REVIEWED CE You can earn two hours of Continuing Education credit from Kansas State University by answering the following questions on canine anaplasmosis. Circle only the best answer for each question, and transfer your answers to the form on page 223 or take the test online at http://outreach.ksu.edu/ce/. This test expires May 1, 2009. Article #2 1. Ehrlichia equi, Ehrlichia phagocytophila, and the agent of human granulocytic ehrlichiosis are now all known by which of the following names? a. Anaplasma platys b. Anaplasma centrale c. Anaplasma phagocytophila d. Anaplasma phagocytophilum e. Anaplasma marginale 4. Which statement is false? a. Ehrlichia ewingii infection is readily diagnosed by using serologic assays. b. Dogs can be A. phagocytophilumseropositive without clinical evidence of infection. c. An IFA assay or the SNAP 4Dx test can be used to diagnose exposure to A. phagocytophilum. d. Nucleic acid detection by PCR is a speciﬁc method to diagnose several tick-borne infections. e. Antibodies produced in response to E. ewingii infection are unlikely to cross react with A. phagocytophilum antigens in serologic assays. 8. During thrombocytopenic episodes seen with infectious cyclic thrombocytopenia: a. Platelet counts are marginally decreased (> 80,000/µl) for one or two days. b. Platelet counts are marginally decreased (> 80,000/µl) for 30 days. c. Platelet counts are found to be normal if counted manually. d. Platelet counts are severely decreased (< 20,000/µl) for one or two days. e. Platelet counts are severely decreased (< 20,000/µl) for 30 days. 2. Which statement is false? a. Most disease outbreaks due to A. phagocytophilum infection are seasonal, coinciding with the emergence of the tick vectors. b. Anaplasma phagocytophilum is transmitted by the same tick that transmits the agent of Lyme disease (Borrelia burgdorferi). c. Anaplasma phagocytophilum has a limited mammalian host range, infecting only dogs. d. Fever, malaise, anorexia, reluctance to move, and joint pain are common clinical signs during acute disease due to A. phagocytophilum infection. e. Clinical signs due to A. phagocytophilum infection may be indistinguishable from those due to Lyme disease and those due to E. ewingii infection. 5. Which of the following samples is necessary for diagnosing A. phagocytophilum infection by nucleic acid detection using PCR? a. Serum ideally collected before antibiotic treatment b. Serum ideally collected after antibiotic treatment c. Anticoagulated whole blood ideally collected before antibiotic treatment d. Anticoagulated whole blood ideally collected after antibiotic treatment e. Buccal mucosal swab ideally collected after antibiotic treatment 9. A positive Anaplasma phagocytophilum SNAP 4Dx test reaction may be seen after exposure to which pair of tick-borne bacteria? a. Anaplasma phagocytophilum and Anaplasma platys b. Anaplasma phagocytophilum and Borrelia burgdorferi c. Anaplasma phagocytophilum and Ehrlichia canis d. Anaplasma phagocytophilum and Ehrlichia chaffeensis e. Anaplasma phagocytophilum and Ehrlichia ewingii 6. Resolution of clinical signs due to A. phagocytophilum infection usually occurs within one or two days after use of which antibiotic? a. Metronidazole b. Clindamycin c. Tylosin d. Netilmicin e. Doxycycline 3. Intracellular morulae may be identiﬁed in circulating canine neutrophils during acute infection by which pair of the following tick-borne bacteria? a. Anaplasma phagocytophilum and Anaplasma platys b. Anaplasma phagocytophilum and Borrelia burgdorferi c. Anaplasma phagocytophilum and Ehrlichia canis d. Anaplasma phagocytophilum and Ehrlichia chaffeensis e. Anaplasma phagocytophilum and Ehrlichia ewingii 10. Which condition or drug is not associated with more severe clinical disease due to Anaplasma species infection? a. Coinfection with other tick-borne bacteria (e.g. Ehrlichia, Bartonella, or Borrelia species) b. Immunosuppression due to concurrent disease or physiologic states (e.g. pregnancy) c. Glucocorticoid administration d. Stress e. Doxycycline administration 7. Infectious cyclic thrombocytopenia in dogs is caused by: a. Anaplasma platys b. Anaplasma centrale c. Anaplasma ovis d. Anaplasma phagocytophilum e. Anaplasma marginale 222 April 2008 VETERINARY MEDICINE http://outreach.ksu.edu/ce/

Table of Contents Feed for the Digital Edition of Veterinary Medicine - April 2008

Veterinary Medicine - April 2008 Contents Letters Leading Off The Veterinary Medicine Interview: Dr. Barrak Pressler Idea Exchange Help! My Dog Licks Everything An Update on Anaplasmosis in Dogs CE Form Advertiser Index Marketplace/Classifieds Mind Over Miller

Veterinary Medicine - April 2008

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