Veterinary Medicine - August 2007 - (Page 545)

ics. Vet Clin North Am Small Anim Pract 2004;34:739-753. 6. Yu-Speight AW, Kern TJ, Erb HN. Ciprofloxacin and ofloxacin aqueous humor concentrations after topical administration in dogs undergoing cataract surgery. Vet Ophthamol 2005;8:181-187. 7. Mather R, Karenchak LM, Romanowski EG, et al. Fourth generation fluoroquinolones: new weapons in the arsenal of ophthalmic antibiotics. Am J Ophthalmol 2002;133:463-466. 8. Kern TJ. Antibacterial agents for ocular therapeutics. Vet Clin North Am Small Anim Pract 2004;34:655-668. 9. Galle LE. Antiviral therapy for ocular viral disease. Vet Clin North Am Small Anim Pract 2004;34:639-653. 10. Fontenelle J, Powell C, Gionfriddo J, et al. Effect of topical cidofovir on experimentally induced FHV-1 conjunctivitis (abstract). Vet Ophthalmol 2005;8:444. 11. Thomasy S, Maggs D, Lim C, et al. Safety and efficacy of famciclovir in cats infected with feline herpesvirus 1, in Proceedings. 37th Annu Conf Am Coll Vet Ophthalmol 2006;43. 12. Stiles J, Townsend WM, Rogers QR, et al. Effect of oral administration of L-lysine on conjunctivitis caused by feline herpesvirus in cats. Am J Vet Res 2002;63:99-103. 13. King TC, Gum GG, Gelatt KN. Evaluation of a topically administered carbonic anhydrase inhibitor (MK-927) in normotensive and glaucomatous beagles. Am J Vet Res 1991;52:2067-2070. 14. Gelatt KN, MacKay EO. Changes in intraocular pressure associated with topical dorzolamide and oral methazolamide in glaucomatous dogs. Vet Ophthalmol 2001;4:61-67. 15. Studer ME, Martin CL, Stiles J. Effects of 0.005% latanoprost solution on intraocular pressure in healthy dogs and cats. Am J Vet Res 2000;61:1220-1224. 16. Xalatan [package insert]. Pharmacia and Upjohn, Division of Pfizer Inc., New York, NY. 17. Carvalho AB, Laus JL, Costa VP, et al. Effects of travoprost 0.004% compared with latanoprost 0.005% on the intraocular pressure of normal dogs. Vet Ophthalmol 2006;9:121–125. 18. Willis AM, Diehl KA, Hoshaw-Woodard S, et al. Effects of topical administration of 0.005% latanoprost solution on eyes of clinically normal horses. Am J Vet Res 2001;62:1945-1951. EXTRA Check out for advice on managing dacryocystitis in dogs. CE You can earn two hours of Continuing Education credit from Kansas State University by answering the following questions on new ophthalmic therapies. Circle only the best answer for each question, and transfer your answers to the form on page 546. d. Idoxuridine and trifluridine e. Cidofovir and famciclovir a. They cure glaucoma. b. Combining dorzolamide with oral methazolamide does not result in a greater decrease in IOP than administration of either product alone. c. They help prevent IOP increases in the normotensive eye of patients with unilateral primary glaucoma. d. Topical beta-blockers decrease aqueous humor production. e. They include systemic carbonic anhydrase inhibitors, topical betablockers, and prostaglandin analogues. Article #2 1. Which tear substitute is the best choice for owners who can only apply medications once a day? a. Petroleum-based artificial tear ointments b. GenTeal c. Lubrithal d. I-Drop Vet e. I-Drop Vet Plus 5. Which statement about topical fluoroquinolones is false? a. They can be effective in treating gram-negative infections involving the cornea. b. Gatifloxacin, ofloxacin, and ciprofloxacin can penetrate an intact corneal epithelium. c. Fluoroquinolones are effective against Pseudomonas species and Escherichia coli. d. They include 0.3% ofloxacin, norfloxacin, gatifloxacin, and ciprofloxacin. e. They should be used for routine antimicrobial prophylaxis. 2. Which tear substitutes contain sodium hyaluronate? a. GenTeal and I-Drop Vet Plus b. GenTeal and Lubrithal c. Lubrithal and I-Drop Vet d. I-Drop Vet and I-Drop Vet Plus e. None of the above 9. Which drug combines dorzolamide and timolol? a. Latanoprost b. Cosopt c. GenTeal d. Tacrolimus e. Sirolimus 3. Which statement about tacrolimus is true? a. It should be used in all patients with KCS. b. It should be reserved for patients with KCS that are sensitive to or not responding well to cyclosporine. c. The severe and PF formulations are preferred since they contain the highest concentration of hydroxypropyl methylcellulose. d. It is available over the counter. e. It is similar to lysine both in structure and action. 6. Which drug must be compounded for ophthalmic use? a. Trifluridine b. Cidofovir c. 2% Dorzolamide d. Famciclovir e. None of the above 10. Which statement about prostaglandin analogues is false? a. They are highly effective ocular hypotensive agents with a rapid onset. b. They decrease IOP by increasing outflow through the uveoscleral or unconventional outflow pathway. c. They have been proven effective in decreasing IOP in cats. d. The most commonly used prostaglandin analogues are latanoprost, bimatoprost, and travoprost. e. They cause marked miosis and mild breakdown of the blood-aqueous barrier. 7. Which statement about lysine is correct? a. It can increase the time between recurrences of clinical signs of herpesvirus infection. b. It should be administered with food. c. If given on an empty stomach, it may induce vomiting. d. Multiple formulations are available. e. All of the above 4. Which two drugs are under investigation for use as lacrimostimulants? a. Lubrithal and tacrolimus b. GenTeal and I-Drop Plus c. Pimecrolimus and sirolimus 8. Which statement about glaucoma medications is false? VETERINARY MEDICINE August 2007 545 http://www.vetstreamcanis.com/ACI/August/VMD1/dis00386.asp

Table of Contents Feed for the Digital Edition of Veterinary Medicine - August 2007

Contents A Veterinary Medicine Interview Veterinary Voices Idea Exchange Diagnosis and Treatment of Solar Dermatitis in Dogs Diagnostic Imaging for Linear Foreign Bodies in Cats Overcoming the Diagnostic and Therapeutic Challenges of Canine Immune-Mediated Thrombocytopenia Ophthalmic drugs: What’s new? CE Form Product Preview Advertiser Index Marketplace/Classifieds Mind Over Miller

Veterinary Medicine - August 2007

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