Veterinary Medicine - October 2008 - (Page P7)

Table 1: Antibiotics for treatment of staphylococcal pyoderma Poor choices Poor choices due to frequent resistance of coagulase-positive Staphylococcus strains: • Ampicillin • Amoxicillin • Penicillin • Other non-penicillinase resistant penicillins • Tetracyclines • Non-potentiated sulfa drugs. Adequate choices Adequate initial choices for staphylococcal pyoderma, but 10% to 30% of staphylococcal strains will be resistant. These are also poor choices for prolonged or repeated use because of the likelihood of drug resistance development over time. The potentiated sulfa drugs have been more often associated with idiosyncratic adverse drug reactions, so some clinicians avoid them. Drug Dosage Clindamycin Erythromycin Lincomycin Trimethoprim-sulfa combinations 5.5 to 11 mg/kg po b.i.d. 10 to 15 mg/kg po t.i.d. 22 mg/kg po b.i.d. 15 to 30 mg/kg po b.i.d. Good choices Antibiotics that are good initial choices for pyoderma and that are generally good choices for prolonged or repeated use, because of apparent diﬃculty with which drug resistance develops over time. Note that some dermatologists recommend a higher-than-labeled dose for amoxicillin-clavulanic acid (given below) in treating skin infections. Client compliance is likely to be better with injectable cefovecin or once-daily cefpodoxime. Drug Dosage Amoxicillin-clavulanic acid Cefovecin Cefpodoxime Cephalexin 15 to20 mg/kg po b.i.d. to t.i.d. 8 mg/kg subcutaneously, repeated in 14 days if indicated 5 to10 mg/kg po s.i.d. 22 to30 mg/kg po b.i.d. Additional choices Antibiotics that are often eﬀective for staphylococcal infections but that should not be used for routine cases. Reserve these antibiotics for unusual situations such as methicillin-resistant staphylococci (chloramphenicol) or nonstaphylococcal infections—such as Pseudomonas (ﬂuoroquinolones). Note the ﬂexible dosage range for the ﬂuoroquinolones; the correct dose to use is ideally based on the minimal inhibitory concentration (MIC) of the organism, but in general is the highest for Pseudomonas and midrange for staphylococci. Drug Dosage Chloramphenicol Enroﬂoxacin Marboﬂoxacin Orbiﬂoxacin 40 to 50 mg/kg po t.i.d. 5 to 20 mg/kg po s.i.d. 2.75 to 5.5 mg/kg po s.i.d. 2.5 to 7.5 mg/kg po s.i.d. SPONSORED BY PFIZER ANIMAL HEALTH 7

Table of Contents Feed for the Digital Edition of Veterinary Medicine - October 2008

Veterinary Medicine - October 2008 Contents Leading Off Clinical Exposures Idea Exchange Stalking Stones Vaginitis in Dogs CE Form Advertiser Index Marketplace/Classifieds Mind Over Miller

Veterinary Medicine - October 2008

Veterinary Medicine - October 2008 - Veterinary Medicine - October 2008 (Page Cover1) Veterinary Medicine - October 2008 - Veterinary Medicine - October 2008 (Page Cover2) Veterinary Medicine - October 2008 - Veterinary Medicine - October 2008 (Page 527) Veterinary Medicine - October 2008 - Veterinary Medicine - October 2008 (Page 528) Veterinary Medicine - October 2008 - Contents (Page 529) Veterinary Medicine - October 2008 - Contents (Page 530) Veterinary Medicine - October 2008 - Contents (Page 531) Veterinary Medicine - October 2008 - Contents (Page 532) Veterinary Medicine - October 2008 - Contents (Page 533) Veterinary Medicine - October 2008 - Leading Off (Page 534) Veterinary Medicine - October 2008 - Leading Off (Page 535) Veterinary Medicine - October 2008 - Leading Off (Page 536) Veterinary Medicine - October 2008 - Leading Off (Page 537) Veterinary Medicine - October 2008 - Clinical Exposures (Page 538) Veterinary Medicine - October 2008 - Clinical Exposures (Page 539) Veterinary Medicine - October 2008 - Idea Exchange (Page 540) Veterinary Medicine - October 2008 - Idea Exchange (Page 541) Veterinary Medicine - October 2008 - Stalking Stones (Page 542) Veterinary Medicine - October 2008 - Stalking Stones (Page 543) Veterinary Medicine - October 2008 - Stalking Stones (Page 544) Veterinary Medicine - October 2008 - Stalking Stones (Page 545) Veterinary Medicine - October 2008 - Stalking Stones (Page 546) Veterinary Medicine - October 2008 - Stalking Stones (Page 547) Veterinary Medicine - October 2008 - Stalking Stones (Page 548) Veterinary Medicine - October 2008 - Stalking Stones (Page 549) Veterinary Medicine - October 2008 - Stalking Stones (Page 550) Veterinary Medicine - October 2008 - Stalking Stones (Page 551) Veterinary Medicine - October 2008 - Stalking Stones (Page 552) Veterinary Medicine - October 2008 - Stalking Stones (Page 553) Veterinary Medicine - October 2008 - Stalking Stones (Page 554) Veterinary Medicine - October 2008 - Stalking Stones (Page 555) Veterinary Medicine - October 2008 - Stalking Stones (Page 556) Veterinary Medicine - October 2008 - Stalking Stones (Page 557) Veterinary Medicine - October 2008 - Stalking Stones (Page 558) Veterinary Medicine - October 2008 - Stalking Stones (Page 559) Veterinary Medicine - October 2008 - Stalking Stones (Page 560) Veterinary Medicine - October 2008 - Stalking Stones (Page 561) Veterinary Medicine - October 2008 - Vaginitis in Dogs (Page 562) Veterinary Medicine - October 2008 - Vaginitis in Dogs (Page 563) Veterinary Medicine - October 2008 - Vaginitis in Dogs (Page 564) Veterinary Medicine - October 2008 - Vaginitis in Dogs (Page 565) Veterinary Medicine - October 2008 - Vaginitis in Dogs (Page 566) Veterinary Medicine - October 2008 - Vaginitis in Dogs (Page 567) Veterinary Medicine - October 2008 - Advertiser Index (Page 568) Veterinary Medicine - October 2008 - Marketplace/Classifieds (Page 569) Veterinary Medicine - October 2008 - Marketplace/Classifieds (Page 570) Veterinary Medicine - October 2008 - Marketplace/Classifieds (Page 571) Veterinary Medicine - October 2008 - Marketplace/Classifieds (Page 572) Veterinary Medicine - October 2008 - Marketplace/Classifieds (Page 573) Veterinary Medicine - October 2008 - Mind Over Miller (Page 574) Veterinary Medicine - October 2008 - Mind Over Miller (Page Cover3) Veterinary Medicine - October 2008 - Mind Over Miller (Page Cover4) Veterinary Medicine - October 2008 - Mind Over Miller (Page P1) Veterinary Medicine - October 2008 - Mind Over Miller (Page P2) Veterinary Medicine - October 2008 - Mind Over Miller (Page P3) Veterinary Medicine - October 2008 - Mind Over Miller (Page P4) Veterinary Medicine - October 2008 - Mind Over Miller (Page P5) Veterinary Medicine - October 2008 - Mind Over Miller (Page P6) Veterinary Medicine - October 2008 - Mind Over Miller (Page P7) Veterinary Medicine - October 2008 - Mind Over Miller (Page P8) Veterinary Medicine - October 2008 - Mind Over Miller (Page P9) Veterinary Medicine - October 2008 - Mind Over Miller (Page P10) Veterinary Medicine - October 2008 - Mind Over Miller (Page P11) Veterinary Medicine - October 2008 - Mind Over Miller (Page P12) Veterinary Medicine - October 2008 - Mind Over Miller (Page P13) Veterinary Medicine - October 2008 - Mind Over Miller (Page P14) Veterinary Medicine - October 2008 - Mind Over Miller (Page P15) Veterinary Medicine - October 2008 - Mind Over Miller (Page P16) http://digital.dvm360.com/nxtbooks/advanstar/vm_200912_v2http://digital.dvm360.com/nxtbooks/advanstar/vm_200912http://digital.dvm360.com/nxtbooks/advanstar/vm_200911http://digital.dvm360.com/nxtbooks/advanstar/vm_200910http://digital.dvm360.com/nxtbooks/advanstar/vm_200909http://www.nxtbook.com/nxtbooks/advanstar/vm_200908http://www.nxtbook.com/nxtbooks/advanstar/vm0609http://www.nxtbook.com/nxtbooks/advanstar/vm0509http://www.nxtbook.com/nxtbooks/advanstar/vm0409http://www.nxtbook.com/nxtbooks/advanstar/vm0309http://www.nxtbook.com/nxtbooks/advanstar/vm0209http://www.nxtbook.com/nxtbooks/advanstar/vm0109http://www.nxtbook.com/nxtbooks/advanstar/vm1208http://www.nxtbook.com/nxtbooks/advanstar/vm1108http://www.nxtbook.com/nxtbooks/advanstar/vm1008http://www.nxtbook.com/nxtbooks/advanstar/vm0908http://www.nxtbook.com/nxtbooks/advanstar/vm0708http://www.nxtbook.com/nxtbooks/advanstar/vm0608http://www.nxtbook.com/nxtbooks/advanstar/vm0508http://www.nxtbook.com/nxtbooks/advanstar/vm0408http://www.nxtbook.com/nxtbooks/advanstar/vm0308http://www.nxtbook.com/nxtbooks/advanstar/vm0208http://www.nxtbook.com/nxtbooks/advanstar/vm0108http://www.nxtbook.com/nxtbooks/advanstar/vm1207http://www.nxtbook.com/nxtbooks/advanstar/vm1107http://www.nxtbook.com/nxtbooks/advanstar/vm1007http://www.nxtbook.com/nxtbooks/advanstar/vm0907http://www.nxtbook.com/nxtbooks/advanstar/vm0807http://www.nxtbook.com/nxtbooks/advanstar/vm0707http://www.nxtbook.com/nxtbooks/advanstar/vm0507http://www.nxtbook.com/nxtbooks/advanstar/vm0407http://www.nxtbook.com/nxtbooks/advanstar/vmpshttp://www.nxtbook.com/nxtbooks/advanstar/vm0207http://www.nxtbook.com/nxtbooks/advanstar/vm0107http://www.nxtbook.com/nxtbooks/advanstar/vm1206http://www.nxtbookMEDIA.com

For optimal viewing of this digital publication, please enable JavaScript and then refresh the page. If you would like to try to load the digital publication without using Flash Player detection, please click here.