Veterinary Medicine - November 2008 - (Page 616)

Feline osteoarthritis PEER-REVIEWED between limb function and radiographic osteoarthrosis in dogs with sti e osteoarthrosis. Vet Surg 2003;32(5):451-454. 4. Godfrey DR. Osteoarthritis in cats: a retrospective radiological study. J Small Anim Pract 2005;46(9):425-429. 5. Clarke SP, Bennett D. Feline osteoarthritis: a prospective study of 28 cases. J Small Anim Pract 2006;47(8):439-445. 6. Lascelles BD, Hansen BD, Thomson A, et al. Evaluation of a digitally integrated accelerometer-based activity monitor for the measurement of activity in cats. Vet Anaesth Analg 2008;35(2):173-183. 7. Lascelles BD, Hansen BD, Roe S, et al. Evaluation of client-speci c outcome measures and activity monitoring to measure pain relief in cats with osteoarthritis. J Vet Intern Med 2007;21(3):410-416. 8. Runk A, Kyles AE, Downs MO. Duodenal perforation in a cat following the administration of nonsteroidal anti-in ammatory medication. J Am Anim Hosp Assoc 1999;35(1):52-55. 9. Taylor PM, Delatour P, Landoni FM, et al. Pharmacodynamics and enantioselective pharmacokinetics of carprofen in the cat. Res Vet Sci 1996;60(2):144-151. 10. Parton K, Balmer TV, Boyle J, et al. The pharmacokinetics and effects of intravenously administered carprofen and salicylate on gastrointestinal mucosa and selected biochemical measurements in healthy cats. J Vet Pharmacol Ther 2000;23(2):73-79. 11. Lascelles BD, Henderson AJ, Hackett IJ. Evaluation of the clinical ef cacy of meloxicam in cats with painful locomotor disorders. J Small Anim Pract 2001;42(12):587-593. 12. Gunew MN, Menrath VH, Marshall RD. Long-term safety, ef cacy and palatability of oral meloxicam at 0.01-0.03 mg/kg for treatment of osteoarthritic pain in cats. J Feline Med Surg 2008;10(3):235-241. 13. Sawynok J. Topical and peripherally acting analgesics. Pharmacol Rev 2003;55(1):1-20. 14. Morello CM, Leckband SG, Stoner CP, et al. Randomized double-blind study comparing the ef cacy of gabapentin with amitriptyline on diabetic peripheral neuropathy pain. Arch Intern Med 1999;159(16):1931-1937. 15. Lamont LA, Tranquilli WJ, Mathews KA. Adjunctive analgesic therapy. Vet Clin North Am Small Anim Pract 2000;30(4):805-813,vii. 16. Gaynor JS. Other drugs used to treat pain. In: Gaynor JS, Muir WW, eds. Handbook of veterinary pain management. St. Louis, Mo: Mosby, 2002;251-260. 17. Lee CR, McTavish D, Sorkin EM. Tramadol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states. Drugs 1993;46(2):313-340. 18. Pypendop BH, Ilkiw JE. Pharmacokinetics of tramadol, and its metabolite O-desmethyl-tramadol, in cats. J Vet Pharmacol Ther 2008;31(1):52-59. EXTRAS See for a cat owner fact sheet on arthritis. CE You can earn two hours of Continuing Education credit from Kansas State University by answering the following questions on osteoarthritis in cats. Circle only the best answer for each question, and transfer your answers to the form on page 620 or take the test online at https://outreach.ksu.edu/ce/. This test expires Dec. 1, 2009. c. Limping d. Decreased grooming e. Increased sleep 1. In a recent study that involved examining the radio- graphs of 100 senior cats, what percentage of these cats had evidence of DJD? a. 95% b. 90% c. 80% d. 75% e. 65% 6. Which NSAID has been approved for long-term use in cats in the United States? a. Deracoxib b. Carprofen c. Ketoprofen d. Etodolac e. No NSAIDs have been approved for long-term use. thritis in cats? a. Osteophytes b. Soft tissue mineralization c. Bone remodeling d. Subchondral bone sclerosis e. Articular cartilage deterioration 2. Which statement regarding meloxicam’s status of ap- proval in the United States to treat pain in cats is true? a. The oral formulation is approved for multiple doses for chronic pain. b. The injectable formulation is approved for multiple doses for chronic pain. c. The oral formulation is approved for a single dose only. d. The injectable formulation is approved for a single dose only. e. It is not approved in use for cats. 7. Which is not a radiographic characteristic of osteoar- 3. What is the most common side effect of oral meloxicam in cats? a. Vomiting or diarrhea b. Elevated serum creatinine concentration c. Lethargy d. Elevated ALT activity e. Proteinuria 8. After what age are cats more likely to develop osteoarthritis? a. 5 years b. 6 years c. 8 years d. 10 years e. Development is not age-related. cats with osteoarthritis? a. Gabapentin b. Amitriptyline c. Tramadol d. Meloxicam e. All of the above 4. How are obesity and osteoarthritis related in cats? a. All studies have shown a correlation between excess weight and the development of osteoarthritis. b. All studies have shown no correlation between excess weight and the development of osteoarthritis. c. One study deﬁnitively found a correlation between excess weight and the development of osteoarthritis. d. One study found an association between excess weight and lameness thought to be caused by DJD. e. No studies have looked into whether a correlation exists between excess weight and the development of osteoarthritis. a. Inappropriate elimination b. Hiding 9. Which drug may be beneﬁcial for managing pain in 10. Which measure may need to be taken by owners to help ease the pain of osteoarthritis in cats? a. A weight-loss program for the cat b. Placing food in an easily accessible location c. Placing a ramp up to a favorite elevated resting place d. Increased exercise for the cat with the help of cat toys e. All of the above 5. Which is a not a common sign of osteoarthritis in cats? 616 November 2008 VETERINARY MEDICINE http://www.vetstreamfelis.com/ACI/November08/VMD1/EnglishFactsheet100.asp https://outreach.ksu.edu/ce/

Table of Contents Feed for the Digital Edition of Veterinary Medicine - November 2008

Veterinary Medicine - November 2008 Contents Leading Off Editors' Guest Just Ask the Expert Letters Practice Makes Perfect Clinical Exposures Practice Matters Idea Exchange Author Guidelines A Challenging Case: Esophageal Leiomyoma in a Dog Osteoarthritis in Cats: What We Now Know About Recognition and Treatment Product Preview CE Form/Advertiser Index Marketplace/Classifieds Mind Over Miller

Veterinary Medicine - November 2008

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