The Column - November 2008 - (Page 20)
Market Trends and Analysis The Column www.thecolumn.eu.com November 2008 Market Profile: Capillary electrophoresis (CE), introduced in the 1980s, uses the same principles as gel electrophoresis for the qualitative and quantitative analysis of charged biological molecules, including proteins, carbohydrates and nucleic acids as well as inorganic compounds. CE is very similar in relation to high performance liquid chromatography (HPLC). However, instead of using a pump, CE uses an electromotive force to drive the mobile phase through the capillary tube. The components of a mixture are separated through a horizontal capillary tube made up of fused-silica. When the electric field is applied, the analytes migrate towards the negative electrode, passing through a detector along the way. UV/vis spectroscopy and laser-induced fluorescence (LIF) are the predominant detection methods used for CE. Capillary electrophoresis has become an important tool in many genomics and proteomics laboratories. While academic and government institutions account for the largest use of the technology combining to 41%, the biotech and pharmaceuticals industries account for over a third and are expected to provide the fastest growth. Other industries with significant shares in the CE market include contract research organizations (CRO), hospital/clinical facilities and environmental. While the growth in the academia and government has been somewhat stagnant, the rapid growth in the pharmaceutical and biotech industries is primarily because of CE’s ability to separate chiral and polar compounds. Moreover, automated high-throughput analysis, higher efficiencies and better reproducibility than traditional gel electrophoresis systems has made it a useful analytical tool in the drug discovery process. In fact, many biotech and pharmaceutical companies are transferring their current gel electrophoresis methods to CE. The foregoing data was extracted and adapted from SDi's Global Assessment Report, 10th Edition. For more Author: Glenn Cudiamat E-mail: cudiamat@strategic-directions.com Capillary Electrophoresis 20% Other 18% Pharma 21% Biotech Capillary electrophoresis industrial distrbution information, contact Glenn Cudiamat, vice president of Research Services, Strategic Directions International Inc., 6242 Westchester Parkway, Suite 100, Los Angeles, California 90045, USA, tel. +1 310 641 4982, fax +1 310 641 8851, e-mail: cudiamat@strategic-directions.com 41% Acad/Gov 18
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Table of Contents for the Digital Edition of The Column - November 2008
The Column - November 2008
Contents
Smoke Signals
News
Incognito Method "Non" - Specificiations!
Market Trends and Analysis Market Profile: Capillary Electrophoresis
Simple Differentiation of Black Tea Samples Using a Chemometric Approach
Q&A: The Rise and Rise of Multidimensional GC
The Column - November 2008
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