Professional Section Quarterly - Summer 2012 - (Page 15)

Richard T. Lee, MD Brigham and Women’s Hospital Regulation of endoplasmic reticulum stress by thioredoxininteracting protein Diane J. Mathis, PhD Harvard Medical School Making, breaking, and remaking immunological tolerance Timothy E. McGraw, PhD Weill Cornell Medical College Insulin regulation of the trafficking of the GLUT4 glucose transporter Andrew Miranker, PhD Yale University School of Medicine Molecular determination of the origins of islet amyloid membrane activity K. Sreekumaran Nair, MD, PhD Mayo Clinic, Rochester The impact of chronic poor glycemic control and good glycemic control on oxidative damage of ApoA1 and haptoglobin proteins and functions of HDL in type 1 diabetes Mary-Elizabeth Patti, MD Joslin Diabetes Center Molecular mechanisms of diabetes risk Suzanne R. Pfeffer, PhD Stanford University Rab GTPase control of GLUT4 trafficking in adipocytes Pere Puigserver, PhD Dana-Farber Cancer Institute New components of the insulin signaling pathway and metabolic action: Implications for diabetes Gerald M. Reaven, MD Stanford University Role of insulin resistance and insulin secretion in states of Professional Section Quarterly abnormal carbohydrate metabolism in human disease A. Dean Sherry, PhD University of Texas Southwestern Medical Center at Dallas In vivo imaging of beta-cell function with a zinc-responsive contrast agent Steven E. Shoelson, MD, PhD Joslin Diabetes Center Interactions between metabolism, the immune system, and the microbiota in type 2 diabetes Alan R. Shuldiner, MD University of Maryland School of Medicine Genomics of type 2 diabetes: Moving beyond GWAS to mechanisms and genome-informed personalized medicine Christian Vaisse, MD, PhD University of California, San Francisco Molecular genetics of human obesity ▲ Note: This list is as of August 3, 2012. Clinical News cont. from page 11 Providers pay only the cost of shipping. To learn about ADA’s Safe at School Campaign, see dia betes.org/safeatschool. If you have any questions or comments about the campaign or the toolkit, please contact Crystal Jackson at CJackson@diabetes.org. Action Briefs ■ ADA and the American Heart Association (AHA) have released a scientific statement on the use of nonnutritive sweeteners in the United States. A follow-up to AHA’s recommendation to reduce consumption of added sugars, the new statement addresses nonnutritive sweeteners’ potential to help people reach and maintain a healthy body weight, thereby reducing the risk of cardiovascular disease and obesity. The statement focuses on six widely used sweeteners regulated as food additives by the Food and Drug Administration. The writing group’s in-depth literature review looked at relevant data on consumer attitudes; consumption patterns; appetite, hunger, and energy intake; body weight; and components of cardiometabolic syndrome. After calling for further research in several areas, the statement concludes that there are insufficient data to determine whether use of these sweeteners to replace caloric sweeteners reduces intake of added sugars or carbohydrates, or has clear beneficial health effects. However, the statement notes, some data suggest that substituting nonnutritive sweeteners for added sugars may result in modest energy-intake reductions and weight loss. The statement appears in the August issues of Diabetes Care and Circulation. ■ Last fall, ADA and the American Association of Diabetes Educators convened a broadbased task force to review the national standards for diabetes self-management education, which are updated every five years. The group—which included clinical experts, researchers, nurses, dietitians, and people with diabetes— revised the standards based on current evidence and expert consensus. The standards will be published jointly in Diabetes Care and Diabetes Educator, most likely in November. ▲ 15 http://diabetes.org/safeatschool http://diabetes.org/safeatschool

Table of Contents for the Digital Edition of Professional Section Quarterly - Summer 2012

Professional Section Quarterly - Summer 2012