Family Doctor 2008

AFLURIA®, Inﬂuenza Virus Vaccine Suspension for Intramuscular Injection, contains only a limited quantity of egg protein, this protein can induce immediate hypersensitivity reactions among persons who have severe egg allergy. Allergic reactions include hives, angioedema, allergic asthma, and systemic anaphylaxis (see Contraindications [4]). The 1976 swine inﬂuenza vaccine was associated with an increased frequency of GBS. Evidence for a causal relation of GBS with subsequent vaccines prepared from other inﬂuenza viruses is unclear. If inﬂuenza vaccine does pose a risk, it is probably slightly more than one additional case per 1 million persons vaccinated. Neurological disorders temporally associated with inﬂuenza vaccination, such as encephalopathy, optic neuritis/neuropathy, partial facial paralysis, and brachial plexus neuropathy, have been reported. Microscopic polyangiitis (vasculitis) has been reported temporally associated with inﬂuenza vaccination. 7 DRUG INTERACTIONS 7.1 Concurrent Use With Other Vaccines There are no data to assess the concomitant administration of AFLURIA® with other vaccines. If AFLURIA® is to be given at the same time as another injectable vaccine(s), the vaccine(s) should be administered at different injection sites. AFLURIA® should not be mixed with any other vaccine in the same syringe or vial. 7.2 Concurrent Use With Immunosuppressive Therapies The immunological response to AFLURIA® may be diminished in individuals receiving corticosteroid or immunosuppressive therapies. 8 USE IN SPECIFIC POPULATIONS 8.1 Pregnancy Pregnancy Category C: Animal reproduction studies have not been conducted with AFLURIA®. It is also not known whether AFLURIA® can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. AFLURIA® should be given to a pregnant woman only if clearly needed. 8.3 Nursing Mothers AFLURIA® has not been evaluated in nursing mothers. It is not known whether AFLURIA® is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when AFLURIA® is administered to a nursing woman. 8.4 Pediatric Use Safety and effectiveness in the pediatric population have not been established. 8.5 Geriatric Use In four clinical studies, 343 subjects ages 65 years and older received AFLURIA®. Hemagglutination-inhibiting (HI) antibody responses in geriatric subjects were lower after administration of AFLURIA® in comparison to younger adult subjects (see Clinical Studies [14]). Adverse event rates were generally similar in frequency to those reported in subjects ages 18 to less than 65 years, although some differences were observed (see Adverse Reactions [6.2]). Manufactured by: CSL Limited Parkville, Victoria, 3052, Australia US License No. 1764 Distributed by: CSL Biotherapies Inc. King of Prussia, PA 19406 USA AFLURIA is a registered trademark of CSL Limited. Based on June 2008 revision. familydoctor YOUR ESSENTIAL GUIDE TO HEALTH AND WELLBEING BOSTON HANNAH INTERNATIONAL PUBLISHER AND CEO Kevin Harrington PRESIDENT USA Glenn Oakley PUBLISHING MANAGER Earl Ayers MANAGING EDITOR Charles Ford SUB EDITOR Michelle Hayes DESIGNERS Rula Khatib-Yanis, Terence Sullivan, Gwen Bajon PRODUCTION MANAGER Joanna Harrington PRODUCTION CONTROLLER Katie Mulhern PRODUCTION ADMINISTRATOR Shinead Cooke ADMINISTRATION USA Keisha Hamilton ACCOUNTS MANAGER Zac Tomris ADVERTISING SALES B Hannah LLC, 9th Floor, 274 Madison Avenue, New York NY 10016 USA. Tel: (212) 889-8191, e-mail: familydoctor@contractpublishing.com Family Doctor: Your Essential Guide to Health and Wellbeing is published by the American Academy of Family Physicians and Boston Hannah International © 2008 American Academy of Family Physicians and Boston Hannah International. All rights reserved. Reproduction without the written permission of the Publishers is strictly forbidden. Editorial office: AAFP, 11400 Tomahawk Creek Parkway, Leawood, Kan. 66211, USA. Tel: (913) 906-6000, e-mail: familydoctorbook@aafp.org 2008 Printed in the USA AMERICAN ACADEMY OF FAMILY PHYSICIANS — EDITORIAL STAFF MEDICAL EDITOR Robert B. Kelly, M.D., M.S., Associate Director and Curriculum Coordinator, Fairview Hospital/Cleveland Clinic Family Medicine Residency Program and Associate Professor of Family Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio EDITOR-IN-CHIEF Karen I. Montemayor, Senior Associate Editor, Online and Custom Publishing, American Academy of Family Physicians CONTRIBUTING WRITERS Barbara L. Bittner; Cindy Borgmeyer; James Michael Brodie; Leslie Champlin; Roberta Friedman, Ph.D.; Sarah D. Garber; Angelike M. Gaunt; Kelly L. Gilmore; Susanna E. Guzman; Leigh McKinney; Sarah McMullen, M.Ed., CHES; Karl Michelbach; Karen I. Montemayor; Mark Moran, M.P.H.; Karen Rafinski; Amy Ronek; Anne L. Rubeck; Marilyn Seiger; Sarah Smiley Young; Marijke Vroomen-Durning, R.N.; Sarah J. West; Ashley White AMERICAN ACADEMY OF FAMILY PHYSICIANS — EXECUTIVE STAFF EXECUTIVE VICE PRESIDENT Douglas E. Henley, M.D. VICE PRESIDENT, PUBLISHING & COMMUNICATIONS Michael D. Springer DIVISION DIRECTOR, ONLINE AND CUSTOM PUBLISHING Leigh McKinney familydoctor 2008 11

Table of Contents Feed for the Digital Edition of Family Doctor 2008

Family Doctor 2008 Foreward Introduction Contents What Do You Want From Health Care? Confident Communication Need a New Doctor? Understanding Your Health Insurance OTC Safety as Simple as 1-2-3 The Fight Against Resistance Drug Interactions Prevention is Better than Cure Hitting a Home Run 'The Herbalist Will See You Now' Healthy Eating to Boost Your Heart and Health Exercise: The Elixir of Life Back from the Brink Taking Control Up All Night Vitamins and Minerals 101 Allergies: Combating the Causes Protect Yourself From Colds and the Flu Diabetes: Assessing Your Risk Dealing with Diabetes The Cholesterol Count Getting a Grip on Hypertension Facts About CKD Banish the Burn Easing the Pain Stop the Pounding Urinary Tract Infections: Common and Preventable Skin Essentials The ABCs of COPD Impotence: Tackling the Old Taboo Taking Responsibility for Your Health Prostate Cancer Screening: Is it For You? Protecting Your Prostate Heart Disease and Women: Know the Risks Birth Control to Suit You Maneuvering Through Menopause Help for PMS Infertility: Problems Having a Baby Preventive Health: What Women Need to Know Pregnancy: Taking Care of You and Your Baby Eating for Two Postpartum Mood Disorders The Basics of Breast Milk Newborn Screening Tests: Possible Lifesavers Common Newborn Conditions Childhood Vaccines: Why They're Necessary Food Allergies: The Facts Facing Your Acne Raising Grades Staying On Your Feet Age Gracefully: Take Care of Your Bones Battling Osteoarthritis Tackling Anxiety Beating the Blues

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