Digest This - Special Edition 2008 - (Page 22)

cleveland clinic David g. Jagelman inherited colorectal cancer Registries For more than 25 years, Cleveland Clinic has been using its David G. Jagelman Inherited Colorectal Cancer Registries to follow high-risk colorectal cancer patients and families. The Jagelman Registries — one of the largest registries in the world — and its associated High-Risk Hereditary Colon Cancer Clinic have served as a successful model of care for people with hereditary colon cancer and their at-risk relatives. Individuals with multiple cases of colorectal cancer in their families or with an inherited colorectal cancer syndrome such as hereditary non-polyposis colorectal cancer, familial adenomatous polyposis, Peutz-Jeghers syndrome, and juvenile polyposis, are eligible to participate in the registry. Registry coordinators advocate for patients, encouraging them to act diligently with respect to cancer screening and surveillance. Participation in the registry also gives patients access to education, research and the newest clinical trials. Risk assessment, and genetic counseling and testing are available through the Medical Genetics Program at Cleveland Clinic. Confidentiality is fully protected. In 2007, the registry continued growth with 55 new familial adenomatous polyposis (FAP) families, one new juvenile polyposis (JP) family, two Peutz-Jeghers syndrome (PJS) families and 14 MyH-associated polyposis/ other polyposis families consenting to the registries. Additionally, individuals may wish to participate in Pictured below: Carol A. Burke, MD, and James M. Church, MD, interact with patients enrolled in the Jagelman Registries. The Jagelman Registries continue to enroll patients in a registry-based observation study that is assessing clinical outcomes in FAP patients receiving celecoxib compared with control patients. To date, 32 patients have been enrolled in this study. Patient enrollment also continues in a study involving the prospective analysis of computed tomographic (CT) colonography in the evaluation of FAP To date, 10 patients are enrolled in . this study. In August 2007, we began enrolling patients in a prospective study of the correlation between FAP and intellectual performance. Currently, 30 patients are enrolled in this study. With its detailed family histories and patient medical records, the Jagelman Registries also allows Digestive Disease Institute physicians to offer appropriate care for our hereditary colorectal cancer patients. our High-Risk Clinic, designed for anyone with a strong family history of colorectal cancer, was expanded to twice a month due to a growing demand, and Jon Vogel, MD, was added to our staff. High-Risk Clinic patients can see specialists from the Digestive Disease Institute, the departments of Medical Genetics, General Surgery and nutrition, and the Jagelman Registries. In 2007, High-Risk Clinic specialists saw 104 patients and performed 12 colonoscopies, 49 flexible sigmoidoscopies and 45 esophagogastroduodenoscopies. With the collaboration of genetic counselors, 20 patients were also seen by our Medical Genetics Department. For more information about the Jagelman Registries or to find out a patient’s eligibility, call Lisa LaGuardia at 216.444.6470 or email laguarl@ccf.org. the Collaborative Family Registry for Colorectal Cancer Studies (C-CFR). The C-CFR is the largest registry of its kind, which studies the genetic and lifestyle causes of colorectal cancer. Participants are entitled to a free genetic counseling session and remain informed about the most recent developments in colorectal cancer research. {22} Digest This Special Edition | 2008

Table of Contents Feed for the Digital Edition of Digest This - Special Edition 2008

Digest This - Special Edition 2008 Table of Contents Investigations Institute Overview Innovations Staff Research

Digest This - Special Edition 2008

For optimal viewing of this digital publication, please enable JavaScript and then refresh the page. If you would like to try to load the digital publication without using Flash Player detection, please click here.