Simponi - (Page P1)
SIMPONI™ is indicated for the treatment of 1: Rheumatoid Arthritis Moderately to severely active RA in adults, in combination with methotrexate Psoriatic Arthritis Active PsA in adults, alone or in combination with methotrexate Ankylosing Spondylitis Active AS in adults SIMPONI™ is Competitively Priced As of December 2009, the Estimated Annual WAC Cost for Subcutaneous Anti-TNF Agents for Adult Rheumatoid Arthritis1-5 (certolizumab pegol) Cimzia®* (etanercept) (adalimumab) Enbrel®* Humira®* SIMPONI™† (golimumab) Biologic Cimzia® Cost Comparison Assumptions Dosing 400 mg (2 x 200 mg) initially and at Weeks 2 and 4, followed by 200 mg every other week; for maintenance dosing, 400 mg (2 x 200 mg) every 4 weeks can be considered 50 mg weekly or 25 mg twice weekly 40 mg every 2 weeks 50 mg monthly Pricing WAC per 400 mg (2 x 200 mg): $1462.66 $25K $20K $15K $10K $5K 0 Initial Year $20,477 $18,642 $20,190 Maintenance Year $19,015 Maintenance Year $19,812 Maintenance Year $19,826 Maintenance Year Enbrel® Humira® SIMPONI™ WAC per 50 mg: $388.26 WAC per 40 mg: $761.99 WAC per 50 mg: $1652.18 * Indicated trademarks are registered trademarks of their respective owners. † Pricing for SIMPONITM does not reflect the additional cost of MTX therapy. • This presentation is not intended to compare the relative safety, efficacy, or indications of these treatments. Please refer to the Prescribing Information for each agent Distribution1,5 SIMPONI™ NDC No. WAC Unit Price 50 mg/0.5 mL single dose SmartJect™ autoinjector 50 mg/0.5 mL single dose prefilled syringe 57894-070-02 57894-070-01 $1652.18 $1652.18 Distribution through a broad network of pharmacies SIMPONI™ (golimumab) is distributed directly through wholesalers, who sell it to specialty pharmacies, retail pharmacies, hospitals, and the Department of Veterans Affairs and Department of Defense. Patients can access SIMPONI™ primarily through a broad network of specialty pharmacies and retail pharmacies, with the option of delivery to the patient’s home or other convenient location. Specialty pharmacies also offer patient compliance tools and tracking mechanisms. RefeRenceS 1. SIMPONI™ (golimumab) Prescribing Information. Centocor Ortho Biotech Inc. 2. Cimzia® (certolizumab pegol) Prescribing Information. UCB, Inc. 3. Enbrel® (etanercept) Prescribing Information. Immunex Corporation. 4. Humira® (adalimumab) Prescribing Information. Abbott Laboratories. 5. AnalySource®, First DataBank. December 2009. Please see Important Safety Information on following page and accompanying full Prescribing Information and Medication Guide.
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