ASH News Daily 2012 - Sunday, December 9, 2012 - (Page A-3)
Sunday, December 9, 2012
THROMBOSIS
Upping the Ante on Newer Anticoagulants
BY MARC J. KAHN, MD, MBA
over. Initially introduced as a rodenticide
in 1948, and approved
for human use in 1954, warfarin remains
the most widely prescribed
oral anticoagulant in North America.
The question remains, however,
for how long?
Tomorrow’s Education Program
session, “The New Era in Antithrombotic
Therapy,” will be held from
7:00 to 8:30 a.m. in the Sidney Marcus
Auditorium, Level 4, Building
A, in the Georgia World Congress
Center. The session will be repeated
in the afternoon, from 2:45 to 4:15
p.m. in the same location. Jeffrey I.
Weitz, MD, from McMaster University
in Hamilton, Ontario, will chair
the session. Dr. Weitz, professor of
medicine and executive director of
the Thrombosis and Atherosclerosis
Research Institute in Canada, is a
noted expert in the biochemistry of
coagulation and has been involved
in a number of clinical trials investigating
the role of anticoagulants
in managing thrombotic disorders.
When asked about the focus of the
session, he responded, “New antithrombotic
drugs are changing the
way we manage patients with arterial
and venous thrombosis. Aimed
at the clinician, this session will provide
an update on not only when
and how to use the novel agents,
but also when not to use them.”
Dr. Weitz will give the first lecture
in this session. His talk will focus on
the pharmacology of the newer oral
anticoagulants. He will also discuss
current indications for these new
drugs and will provide information
to allow clinicians to use the right
drug, for the right purpose, at the
right time.
Alan K. Jacobson, MD, from V.A.
Loma Linda Healthcare System,
will lead the second part of the session
and will be discussing the future
of warfarin. Dr. Jacobson, a cardiologist
and associate chief of staff
for research, has been director of the
Cardiology Anticoagulation Clinic.
He has seen the initiation and de-
T
Meet the New
Blood Editor
Mark your calendar to stop
by the ASH booth (#3105)
tomorrow from 12:30 to
1:30 p.m. to meet Dr. Bob
Löwenberg, Blood’s editor-inchief
designee, and
Dr. Nancy Berliner, deputy
editor designee.
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he days of having only warfarin
available as a long-term
oral anticoagulant are long
velopment of point-of-care testing
at Loma Linda and has worked
on patient home testing protocols
for patients on warfarin. Dr. Jacobson
will also discuss the role of the
newer agents in the management of
non-valvular atrial fibrillation.
The third part of this Education
session will concentrate on the simultaneous
use of multiple agents
in patients with cardiovascular disease.
Jessica L. Mega, MD, MPH, a
cardiologist at Brigham and Women’s
Hospital, Boston, MA, will
ASH NEWS DAILY
Page A–3
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serve as the discussant. Dr. Mega
is an investigator for the Thrombosis
In Myocardial Infarction (TIMI)
group and has recently been the
lead author on an article appearing
in the New England Journal of
Medicine discussing the use of rivaroxiban
in patients with acute coronary
syndromes. Dr. Mega will also
discuss the use of triple therapy,
dual antiplatelet therapy plus an
oral anticoagulant, in patients with
atrial fibrillation, acute coronary
syndrome, or recent percutaneous
coronary intervention.
This session is timely as the number
of alternatives to warfarin continues
to expand. The precise role
for newer anti-thrombotics in the
management of atherosclerotic disease,
atrial
fibrillation, and other
thrombotic disorders is in a state
of flux. We anxiously anticipate the
antiquation of the antics of antediluvian
antithrombotic therapies.
Dr. Kahn indicated no relevant conflicts
of interest.
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resources to benefi t you
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ASH News Daily 2012 - Sunday, December 9, 2012
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