ASH News Daily 2013 - Day 2 - (Page A-15)
Advertisement
Attention: Investigators/Physicians
Idelalisib Clinical Trial Program
Recruiting for iNHL and CLL Patients
Idelalisib is an investigational product and its
safety and efficacy have not been established.
Gilead is actively recruiting patients for the WATERFALL clinical program of idelalisib in
indolent Non-Hodgkin's Lymphoma (iNHL) and Chronic Lymphocytic Lymphoma (CLL).
Formerly known as CAL-101 and GS-1101, idelalisib is an oral investigational product
that, based on pre-clinical data, selectively targets phosphatidylinositol 3-kinase (PI3K)
delta. It is being developed both as a single agent and in combination with approved and
investigational therapies.
Of the 10 studies in the WATERFALL program, 4 are currently recruiting patients:
* Relapsed/refractory iNHL
- Study 124 - Phase 3, randomized, double-blind, placebo-controlled study of idelalisib in
combination with rituximab
- Study 125 - Phase 3, randomized, double-blind, placebo-controlled study of idelalisib in
combination with bendamustine and rituximab
* Relapsed/refractory CLL
- Study 115 - Phase 3, randomized, double-blind, placebo-controlled study of idelalisib in
combination with bendamustine and rituximab
- Study 119 - Phase 3, randomized, controlled study of idelalisib in combination with
ofatumumab
Studies of idelalisib in treatment naive CLL patients are planned but not yet recruiting.
- Study 118 - Phase 3, randomized, double-blind, placebo-controlled study of idelalisib in
combination with either rituximab or chlorambucil
- Study 123 - Phase 3, randomized, double-blind, placebo-controlled study of idelalisib in
combination with bendamustine and rituximab
For more information, or to refer patients to a WATERFALL study, visit:
* Exhibition booth 3428
* www.clinicaltrials.gov
The WATERFALL program website can be found at
www.WaterfallStudies.com
The WATERFALL clinical program
reflects Gilead's commitment to
addressing the needs of patients
with significant unmet medical need.
Adverse events will be reported per study requirements.
Gilead_Advertorial_Ash_Nov_V6_071113.indd 1
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Table of Contents for the Digital Edition of ASH News Daily 2013 - Day 2
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ASH News Daily 2013 - Day 2
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