Drug Information Journal - March 2009 - (Page 147) Local Laboratory Reference Intervals MEDICAL INFORMATION 147 130 FIGURE 4 120 Empirical Lower Limit Relative to Central Laboratory URL (=100*expΛi ) Hemoglobin LRL relationship. 110 100 90 80 70 70 75 80 85 90 95 100 105 110 115 Lab Lower Limit Relative to Central Laboratory URL (=100*expL i ) from 175 to 96 and 46 respectively, the correlations and scatter plots were essentially identical. R E S U LT S In Figures 4 and 5, we provide examples for hemoglobin and serum creatinine respectively. The scatter plots of empirical LRL or URL (verti- cal axis) against the relevant actual limit (horizontal axis) indicate whether or not there is a population-based rationale for the choice of local reference limit. If there is a rational basis, the cloud of data points should show a marked trend from lower left to upper right (that is, a significant correla- 170 FIGURE 5 150 Empirical URL Relative to Central Laboratory URL (=100*expΛi ) Creatinine URL relationship. 130 110 90 70 50 50 60 70 80 90 100 110 120 130 140 Lab URL Relative to Central Laboratory URL (=100*expL i ) Drug Information Journal
For optimal viewing of this digital publication, please enable JavaScript and then refresh the page. If you would like to try to load the digital publication without using Flash Player detection, please click here.