Clinical OMICs - Issue 4 - (Page 3)

Innovative Practices, Actionable Results Less art, more science- that's the trend that is being driven by gene sequencing diagnostics. CANCER DIAGNOSTICS LEVERAGE DECREASING COST OF SEQUENCING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Diagnostic companies are investing heavily in computational and informatics platforms in order for genetic sequencing to be of value to clinicians. LABS FACE MEDICARE CUTS, NEW CODES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12 "Protecting Access" looms as biggest challenge since CLIA. Regular Features INNOVATOR . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .16 HARNESSING THE POWER OF EXOSOMES These lipid nanovesicles are garnering attention in diagnostics, for drug delivery, and as research tools. SNAPSHOT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20 A COMMON SENSE DISCUSSION OF PATENTING MEDICAL DIAGNOSTICS Methods such as breakthrough diagnostic tests should be patentable, but the courts may disagree. CASE STUDY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .23 DETECTION AND INTERPRETATION OF RARE SUB-CLONAL CANCER DRIVER MUTATIONS Two new platforms have been designed to target and streamline the identification and the interpretation of somatic variants and driver mutations in cancer. NEWS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 NEW PRODUCTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .19 BEST OF THE WEB . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .28 www.clinicalomics.com May 29, 2014 Clinical OMICs 3 https://www.youtube.com/channel/UCXBPPWZv--Ne4NfAUHcc8hg https://twitter.com/ClinicalOMICs http://www.clinicalomics.com

Table of Contents for the Digital Edition of Clinical OMICs - Issue 4

Contents

Clinical OMICs - Issue 4