Clinical OMICs - Issue 5 - (Page 19)

Clinical OMICs NEW PRODUCTS Companion Dx Robust Prototype Assays Sperm Donor Screening Service Matchright™ is a screening service for families who are planning to use a sperm donor to conceive. Client and donor DNA information is digitally combined to create and analyze the "virtual genome" of a hypothetical child, evaluating risk for over 500 recessive genetic diseases. A next-generation sequencing platform is used to look inside a future child's potential genome to uncover disease risk, and a personalized catalogue of risk-reduced donors is generated for each prospective mother, filtering out donor matches with a high probability for passing on the conditions. GenePeeks www.genepeeks.com Superbug Molecular Screening Test The Acuitas™ MDRO gene test is a molecular screening tool that can identify patients at risk for harboring serious disease-causing microbes that can resist antibiotics. The test can directly detect as many as seven genes from one patient sample and can distinguish specific genes that may aid in therapeutic guidance. The Acuitas MDRO gene test is currently performed at the CLIA-certified OpGen Clinical Services Laboratory in Gaithersburg, Maryland. OpGen www.opgen.com www.clinicalomics.com Three new companion diagnostic robust prototype assays have been launched for the detection of biomarkers PSMA, MDM2, and FGFR for companies exploring novel treatment options for patients with cancer. PSMA (prostate specific membrane antigen) is a cell surface protein that mediates signal transduction processes leading to cell migration. MDM2 ISH (mouse double minute 2) is a gene that encodes a protein that inhibits p53 activation and promotes progression through the cell cycle. FGFR2 (fibroblast growth factor receptor 2) is a receptor tyrosine kinase that is responsible for mediating a number of intracellular processes culminating in cell growth and proliferation. Ventana Medical Systems www.ventana.com Assay for Diagnosing HSV Infection The FDA has cleared the IMDx HSV-1/2 for Abbott m2000 assay, a test that detects and differentiates Herpes Simplex Virus type 1 (HSV-1) and type 2 (HSV-2) DNA from male and female skin lesions from anogenital or oral sites. HSV-1 and HSV-2 are the most common causes of oral and genital lesions and are spread through sexual and skin-to-skin contact. This test is designed for use on Abbott's automated m2000 system. IMDx www.IntelligentMDx.com June 12, 2014 Clinical OMICs 19 http://www.ventana.com http://www.genepeeks.com http://www.IntelligentMDx.com http://www.opgen.com http://www.clinicalomics.com

Table of Contents for the Digital Edition of Clinical OMICs - Issue 5

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Clinical OMICs - Issue 5