Pharmacy Times 2008 OTC Products - (Page 56) Safety of OTC Medications in Pregnant Women continued from page 54 Table 1—Recommended Therapies for the Treatment of Specific Symptoms in Pregnant Women Symptom Pain Nasal Congestion Recommended Therapy* Acetaminophen (Tylenol) 1: Fluids, humidifier, saline nasal drops 2: Oral: pseudoephedrine (Sudafed); Nasal spray: oxymetazoline (Afrin) 1: Fluids, humidifier, saltwater 2: Cough/sore throat: cough drops; Chest congestion: mentholated topical (Vicks VapoRub) 3: Expectorant: guaifenesin (Mucinex, Robitussin); Suppressant: dextromethorphan (Delsym); May use alone or in combination (Robitussin DM) 1: Cromolyn nasal spray (Intal, NasalCrom) 2: Chlorpheniramine (Chlor-Trimeton) 3: Diphenhydramine (Benadryl) 1: Dietary and lifestyle changes 2: Antacids: aluminum hydroxide/ magnesium hydroxide (Mylanta, Maalox); Calcium carbonate (Tums, Rolaids) 3: H2RBs: cimetidine (Tagamet); ranitidine (Zantac); famotidine (Pepcid) Simethicone (Gas-X, Mylanta Gas) 1: Increase dietary fiber, fluids, and exercise 2: Supplemental fiber: Psyllium (Metamucil); Stool softener: Docusate (Colace) 3: Laxatives: Lactulose; Sorbitol; Bisacodyl (Dulcolax); Senna (Senakot); Castor oil Loperamide (Imodium) Meclizine (Antivert; use caution in first trimester) Dimenhydrinate (Dramamine; use caution in third trimester) Bismuth subsalicylate (Pepto-Bismol, Kaopectate) Therapy Not Recommended NSAIDs; Aspirin Avoid pseudoephedrine in first trimester Sore Throat/Cough/ Chest Congestion Avoid menthol-containing cough drops Allergies Loratadine (Alavert, Claritin) Acid Indigestion/GERD Sodium bicarbonate Flatulence Constipation Diarrhea Nausea/Motion Sickness NSAIDs = nonsteroidal anti-inflammatory drugs; GERD = gastroesophageal reflux disease; H2RBs = histamine-2 receptor blockers. *Numbered therapies are listed in order of recommendation (ie, first-line therapy first, etc). OTC Supplement 2008 56 Pharmacy Times
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