MD Conference Express - (Page 39)
for the most at-risk individuals: BMI ≥95th percentile (- 5.5% vs -3.8%; p=0.05) and waist circumference > 90th percentile (-8.1% vs -5.9%; p=0.04) for intervention versus control, respectively. Table 1. BMI (Overall Sample).
Baseline BMI ≥85 Percentile
th
DIABET ES
End of study
Change
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49.3% 50.3%
45.2% 45.8%
-4.1% -4.5% 0.05
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and oring le e Monit valuab vides ts. This Glucos M) pro ien nuous (RT-CGdiabetic pat ve bolus e Conti t oring Real-Tim Treatmenglucose monit patterns inential to impro en and s childr s pot s and er/ Diabete
BMI ≥95th Percentile Control Intervention BMI z-score Control Intervention 0.87 0.90 0.86 0.85 -0.01 -0.05 30.4% 30.1% 26.6% 24.6% -3.8% -5.5%
ong hyp tinuou rs the e trend use of rapy am ns me con ut glucos ement offe Real-ti abo ulin the through the ist clinicia es. ation ic managtrol of ins DM) may ass basal rat inform of glycem d ght con mellitus (T1 data that d use rnight es metho and overni and ove widesprea pective diabet dosing with type 1 s and retros rate ratios ports the hyd rm t sup adults mia ala ulin-to-carbo dence tha e 4. yce hypogl izing ins y provide evi See pag M. im in opt trial data ma ts with T1D Diabetes Recent M in patien tion of ence CG of RT– The Sci Globaliza
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0.04
Reproduced with permission from the HEALTHY Study Group.
In reporting the HEALTHY secondary endpoints for cardiovascular disease risk factors and fitness, Marsha D. Marcus, PhD, University of Pittsburgh, Pittsburgh, PA, referenced data from 2003, which determined that roughly 4% of all adolescents and nearly 30% of overweight adolescents in the United States meet the criteria for metabolic syndrome – the constellation of metabolic dysfunctions that are associated with obesity [Cook et al. Arch Pediatr Adolesc Med 2003]. There were no significant differences in abnormal lipids in intervention versus control. Overall, there was no difference in level of hypertension; however, the intervention showed significant improvements in measures of hypertension for male African-American (p=0.002) and male Caucasian students (p=0.045) but not for male Hispanics. Levels of physical activity were low at baseline and remained so at the end of the study, suggesting that the HEALTHY intervention had a negligible effect in this population. HEALTHY investigators commented that while the intervention did not meet its primary endpoint of altering the combined prevalence of being overweight or obese, it did have moderate effects on obesity and other important risk factors for T2DM. For further details and access to the intervention program materials that were used in the HEALTHY study, go to http://www.healthystudy.org.
The editors would like to thank the many members of the American Diabetes Association presenting faculty who generously gave their time to ensure the accuracy and quality of the articles in this publication.
Highlights from the American Diabetes Association 70th Annual Scientific Sessions
39
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Table of Contents for the Digital Edition of MD Conference Express
MD Conference Express
Contents
Real-Time Continuous Glucose Monitoring and Diabetes Treatment
The Globalization of Diabetes
Treat the Individual, Tend to the Population
Microvascular Outcomes from the ACCORD Trial
Diabetic Retinopathy in the ACCORD Trial
Results from the STAR 3 Study
Findings from HELP PD
Insights from the BARI 2D Trial
Effect of Atorvastatin on Beta Cell Function
Caffeine Supplementation Reduces Exercise Induced Hypoglycemia
Cardiometabolic Risk
Point of Care Devides
Newer Insulins
Diabetes, Glycemia and Cardiovascular Disease: Is it Time to Rethink the Regulatory Approach?
Diabetes and Cancer: ADA Consensus Statement
The Diabetic Foot Wound
HEALTHY Study - Middle School-Based Intervention to Reduce Diabetes Risk
MD Conference Express
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