ATS Pocket Guide 2013 - (Page 9)
DEFINITION OF USUAL INTERSTITIAL
PNEUMONIA PATTERN
HIGH-RESOLUTION COMPUTED TOMOGRAPHY (HRCT) FEATURES
Figure 1 HRCT Images Demonstrating UIP Pattern
1
(A and B) UIP pattern, with extensive honeycombing: axial and coronal HRCT images show basal predominant, peripheral predominant
reticular abnormality with multiple layers of honeycombing (arrows); (C and D) UIP pattern, with less severe honeycombing: axial and
coronal CT images show basal predominant, peripheral predominant reticular abnormality with subpleural honeycombing (arrows);
(E and F) Possible UIP pattern: axial and coronal images show peripheral predominant, basal predominant reticular abnormality with a
moderate amount of ground glass abnormality, but without honeycombing.1
Reprinted with permission of the American Thoracic Society. Copyright © 2013 American Thoracic Society.
Raghu G, Collard H, et al. An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for
Diagnosis and Management. Am J Respir Crit Care Med. 2011; 183: 788–824. Official journal of the American Thoracic Society.
Table 4 HRCT Criteria for UIP Pattern
UIP Pattern
(All Four Features)
Possible UIP Pattern
(All Three Features)
Inconsistent with UIP Pattern
(Any of the Seven Features)
1. Subpleural, basal predominance
2. Reticular abnormality
3. Honeycombing with or without traction
bronchiectasis
4. Absence of features listed as
inconsistent with UIP pattern (see third
column)
1. Subpleural, basal predominance
2. Reticular abnormality
3. Absence of features listed as
inconsistent with UIP pattern (see third
column)
1. Upper or mid-lung predominance
2. Peribronchovascular predominance
3. Extensive ground glass abnormality
(extent >reticular abnormality)
4. Profuse micronodules (bilateral,
predominantly upper lobes)
5. Discrete cysts (multiple, bilateral, away
from areas of honeycombing)
6. Diffuse mosaic attenuation/air-trapping
(bilateral, in three or more lobes)
7. Consolidation in bronchopulmonary
segment(s)/lobe(s)
HRCT = high-resolution computed tomography; UIP = usual interstitial pneumonia.
An American Thoracic Society Pocket Publication 9
Table of Contents for the Digital Edition of ATS Pocket Guide 2013
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