MD Conference Express ISC 2013 - (Page 5)
IN ACuTe ISChemIC STROke, TIme IS BRAIN
Are you reAdy?
Door to treatment in ≤60 minutes is the
standard of care recognized by professional
medical associations1
In 2010, less than 30% of hospitals† achieved
a door-to-treatment time of ≤60 minutes2
For additional ways to make every minute count, visit
www.urgencytotreatais.com.
Indication
Activase (Alteplase) is indicated for the management of acute ischemic
stroke in adults for improving neurological recovery and reducing the
incidence of disability. Treatment should only be initiated within
3 hours after the onset of stroke symptoms, and after exclusion
of intracranial hemorrhage by a cranial computerized tomography
(CT) scan or other diagnostic imaging method sensitive for the
presence of hemorrhage (see CONTRAINDICATIONS in the full
prescribing information).
Important Safety Information
All thrombolytic agents increase the risk of bleeding, including intracranial
bleeding, and should be used only in appropriate patients. Not all patients
with acute ischemic stroke will be eligible for Activase therapy, including
patients with evidence of recent or active bleeding; recent (within 3 months)
intracranial or intraspinal surgery, serious head trauma, or previous stroke;
uncontrolled high blood pressure; or impaired blood clotting.
Please see the Brief Summary on the following
pages for additional Important Safety Information.
ED=emergency department; NIHSS=National Institutes of Health Stroke Scale.
*Activase must be administered within 3 hours of symptom onset.
†
Hospitals participated in the American Heart Association/American Stroke Association
Get With the Guidelines®—Stroke registry.
References: 1. Fonarow GC, Smith EE, Saver JL, et al. Timeliness of tissue-type plasminogen
activator therapy in acute ischemic stroke: patient characteristics, hospital factors, and outcomes
associated with door-to-needle times within 60 minutes. Circulation. 2011;123(7):750-758.
2. Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics–2012 update:
a report from the American Heart Association. Circulation. 2012;125(1):e2-e220.
© 2012 Genentech USA, Inc. All rights reserved. ACI0000648302
http://www.urgencytotreatais.com
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Table of Contents for the Digital Edition of MD Conference Express ISC 2013
MD Conference Express ISC 2013
Contents
Defending the Stroke Guidelines
Stroke Update: An Overview of What Is Going on in the Area of Stroke
Brain Imaging Does Not Help Identify Patients Who May Benefit From Endovascular Treatments for Acute Ischemic Stroke
MISTIE II Trial: 365-Day Results Demonstrate Improved Outcomes and Cost Benefit
Addition of AMPLATZER PFO Occluder to Medical Therapy Is Beneficial in Patients With Cryptogenic Stroke and PFO
Intraoperative CT-Guided Endoscopic Surgery for ICH [ICES]
The EMBRACE Trial: Prolonged Ambulatory Cardiac Monitoring Improves the Detection and Treatment of Atrial Fibrillation in Patients With Cryptogenic Stroke
DP-b99 Does Not Improve Recovery Following Acute Ischemic Stroke
The Secondary Prevention of Small Subcortical Strokes Trial: Blood Pressure Intervention Results
Final Results of the Solitaire FR Thrombectomy for Acute Revascularization: The STAR Trial
Clopidogrel Plus Aspirin Reduces Risk of Recurrent Stroke: The CHANCE Trial
Reversal of Chronic Hypoperfusion to Improve Cognitive Function: The RECON Trial
Cardioembolic Stroke
IMS III
Novel Anticoagulants in Vascular Neurology Practice
Wake-Up Stroke
Virtual Reality in Stroke Rehabilitation
Reward Improves Long-Term Retention of a Motor Memory Through Induction of Offline Memory Gains
MD Conference Express ISC 2013
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