Biotechnology Healthcare - November/December 2008 - (Page U6) Psoriasis has a documented occupational impact, including a negative effect on work productivity, job retention, and the amount of days missed on the job (Schmitt 2006). In addition, more than half of NPF respondents have reported that psoriasis impairs their ability to work, either partially (35 percent) or completely (17 percent) (NPF 2004). An analysis of NPF surveys conducted between 2003 and 2005 found that when compared to patients with mild psoriasis, people with severe psoriasis were more likely to have annual household income of less than $30,000 (Horn 2007b). In addition, another study found that for those patients with severe psoriasis, more than half were not working or retired, and of these patients, 34 percent attributed their inability to retain a job to their disease (Finlay 1995). Employed patients reported having missed a mean of 26 days from work per year as a result of their condition (Finlay 1995). Summary Numerous unmet needs exist among people with psoriasis. In the absence of a cure, psoriasis patients seek treatment that improves signs and symptoms of their disease. Much progress has been made in the area of treatment options, but substantial gaps still exist. References Finlay AY, Coles EC. The effect of severe psoriasis on the quality of life of 369 patients. Br J Dermatol. 1995;132:236–244. Fortune DG, Richards HL, Main CJ, et al. What patients with psoriasis believe about their condition. J Am Acad Dermatol. 1998;39:196–201. Gelfand JM, Neimann AL, Shin DB, et al. Risk of myocardial infarction in patients with psoriasis. JAMA. 2006a;296:1735–1741. Gelfand JM, Shin DB, Neimann AL, et al. The risk of lymphoma in patients with psoriasis. J Invest Dermatol. 2006b;126:2194–2201. Gelfand JM, Troxel AB, Lewis JB, et al. The risk of mortality in patients with psoriasis. Arch Dermatol. 2007;143:1493–1499. Greaves MW, Weinstein GD. Treatment of psoriasis. 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Accessed Oct. 7, 2008. Patel V, Horn EJ, Lobosco SJ, et al. Psoriasis treatment patterns: results of a cross-sectional survey of dermatologists. J Am Acad Dermatol. 2008;58:964–969. Rapp SR, Feldman SR, Exum ML, et al. Psoriasis causes as much disability as other major diseases. J Am Dermatol. 1999;41:401–407. Schmitt JM, Ford DE. Work limitations and productivity loss are associated with health-related quality of life but not with clinical severity in patients with psoriasis. Dermatology. 2006;213: 102–110. 6 http://www.psoriasis.org/about/psoriasis/ http://www.psoriasis.org/research/foundation/survey_panels.php http://www.psoriasis.org/research/foundation/survey_panels.php http://www.psoriasis.org/research/foundation/survey_panels.php http://www.psoriasis.org/research/foundation/survey_panels.php http://www.psoriasis.org/research/foundation/survey_panels.php http://www.psoriasis.org/research/foundation/survey_panels.php http://www.psoriasis.org/research/foundation/survey_panels.php http://www.psoriasis.org/research/foundation/survey_panels.php
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