Managed Care - January 2009 - (Page 1) In moderate-risk* regimens Approach chemotherapy with confidence by reducing the risk of febrile neutropenia Neulasta® (pegfilgrastim) is indicated to decrease the incidence of infection, as manifested by febrile neutropenia, in patients with nonmyeloid malignancies receiving myelosuppressive anticancer drugs associated with a clinically significant incidence of febrile neutropenia. Important Product Safety Information Splenic rupture (including fatal cases), acute respiratory distress syndrome, and sickle cell crises have been reported. Allergic reactions, including anaphylaxis, have also been reported. The majority of these reactions occurred upon initial exposure. However, in rare cases, allergic reactions, including anaphylaxis, recurred within days after discontinuing anti-allergic treatment. In a placebo-controlled trial, bone pain occurred at a higher incidence in Neulasta®-treated patients as compared to placebotreated patients (31% vs. 26%). The most common adverse events reported in either placebo- or active-controlled trials were consistent with the underlying cancer diagnosis and its treatment with chemotherapy, with the exception of bone pain. Please refer to brief summary of Neulasta® Prescribing Information. *Regimens associated with ≥ 17% risk of febrile neutropenia. © 2008 Amgen. All rights reserved. MC41456 02-08 Class I www.neulasta.com Consequences of febrile neutropenia, such as hospitalization, may impact patient care First- and subsequent-cycle Neulasta® achieved significant results in patients receiving a moderate-risk* regimen: ■ 94% reduction in febrile neutropenia vs. placebo (17% vs. 1%).1,2 ■ 93% reduction in febrile neutropenia–related hospitalization vs. placebo (14% vs. 1%).1,2 Start with support http://www.neulasta.com http://www.neulasta.com
Table of Contents Feed for the Digital Edition of Managed Care - January 2009 Managed Care - January 2009 Editor's Memo Contents Legislation & Regulation News and Commentary Medication Management Compensation Monitor Health Care's Disruptive Innovations Q&A With Clayton Christensen 'Disruption' May Be Plans' Best Bet Avoid the PBM Rebate Trap HealthPartners Puts Diabetes on Notice Formulary Files Plan Watch Tomorrow's Medicine Ad Index Outlook Unmet Needs in the Management of Plaque Psoriasis Impact of RSV: Implications for Managed Care Managed Care - January 2009 Managed Care - January 2009 - Managed Care - January 2009 (Page Cover1) Managed Care - January 2009 - Managed Care - January 2009 (Page Cover2) Managed Care - January 2009 - Managed Care - January 2009 (Page Cover2a) Managed Care - January 2009 - Managed Care - January 2009 (Page Cover2b) Managed Care - January 2009 - Managed Care - January 2009 (Page 1) Managed Care - January 2009 - Editor's Memo (Page 2) Managed Care - January 2009 - Editor's Memo (Page 3) Managed Care - January 2009 - Contents (Page 4) Managed Care - January 2009 - Contents (Page 5) Managed Care - January 2009 - Legislation & Regulation (Page 6) Managed Care - January 2009 - Legislation & Regulation (Page 7) Managed Care - January 2009 - News and Commentary (Page 8) Managed Care - January 2009 - Medication Management (Page 9) Managed Care - January 2009 - Medication Management (Page 10) Managed Care - January 2009 - Compensation Monitor (Page 11) Managed Care - January 2009 - Health Care's Disruptive Innovations (Page 12) Managed Care - January 2009 - Health Care's Disruptive Innovations (Page 13) Managed Care - January 2009 - Health Care's Disruptive Innovations (Page 14) Managed Care - January 2009 - Health Care's Disruptive Innovations (Page 15) Managed Care - January 2009 - Health Care's Disruptive Innovations (Page 16) Managed Care - January 2009 - Health Care's Disruptive Innovations (Page 17) Managed Care - January 2009 - Health Care's Disruptive Innovations (Page 18) Managed Care - January 2009 - Health Care's Disruptive Innovations (Page 19) Managed Care - January 2009 - Health Care's Disruptive Innovations (Page 20) Managed Care - January 2009 - Health Care's Disruptive Innovations (Page 21) Managed Care - January 2009 - Q&A With Clayton Christensen (Page 22) Managed Care - January 2009 - Q&A With Clayton Christensen (Page 23) Managed Care - January 2009 - Q&A With Clayton Christensen (Page 24) Managed Care - January 2009 - Q&A With Clayton Christensen (Page 25) Managed Care - January 2009 - 'Disruption' May Be Plans' Best Bet (Page 26) Managed Care - January 2009 - 'Disruption' May Be Plans' Best Bet (Page 27) Managed Care - January 2009 - 'Disruption' May Be Plans' Best Bet (Page 28) Managed Care - January 2009 - 'Disruption' May Be Plans' Best Bet (Page 29) Managed Care - January 2009 - 'Disruption' May Be Plans' Best Bet (Page 30) Managed Care - January 2009 - Avoid the PBM Rebate Trap (Page 31) Managed Care - January 2009 - Avoid the PBM Rebate Trap (Page 32) Managed Care - January 2009 - Avoid the PBM Rebate Trap (Page 33) Managed Care - January 2009 - Avoid the PBM Rebate Trap (Page 34) Managed Care - January 2009 - Avoid the PBM Rebate Trap (Page 35) Managed Care - January 2009 - HealthPartners Puts Diabetes on Notice (Page 36) Managed Care - January 2009 - HealthPartners Puts Diabetes on Notice (Page 37) Managed Care - January 2009 - HealthPartners Puts Diabetes on Notice (Page 38) Managed Care - January 2009 - HealthPartners Puts Diabetes on Notice (Page 39) Managed Care - January 2009 - HealthPartners Puts Diabetes on Notice (Page 40) Managed Care - January 2009 - HealthPartners Puts Diabetes on Notice (Page 41) Managed Care - January 2009 - HealthPartners Puts Diabetes on Notice (Page 42) Managed Care - January 2009 - Formulary Files (Page 43) Managed Care - January 2009 - Plan Watch (Page 44) Managed Care - January 2009 - Plan Watch (Page 45) Managed Care - January 2009 - Plan Watch (Page 46) Managed Care - January 2009 - Tomorrow's Medicine (Page 47) Managed Care - January 2009 - Ad Index (Page 48) Managed Care - January 2009 - Ad Index (Page 49) Managed Care - January 2009 - Outlook (Page 50) Managed Care - January 2009 - Unmet Needs in the Management of Plaque Psoriasis (Page CB-A1) Managed Care - January 2009 - Unmet Needs in the Management of Plaque Psoriasis (Page CB-A2) Managed Care - January 2009 - Unmet Needs in the Management of Plaque Psoriasis (Page CB-A3) Managed Care - January 2009 - Unmet Needs in the Management of Plaque Psoriasis (Page CB-A4) Managed Care - January 2009 - Unmet Needs in the Management of Plaque Psoriasis (Page CB-A5) Managed Care - January 2009 - Unmet Needs in the Management of Plaque Psoriasis (Page CB-A6) Managed Care - January 2009 - Impact of RSV: Implications for Managed Care (Page CB-B1) Managed Care - January 2009 - Impact of RSV: Implications for Managed Care (Page CB-B2) Managed Care - January 2009 - Impact of RSV: Implications for Managed Care (Page CB-B3) Managed Care - January 2009 - Impact of RSV: Implications for Managed Care (Page CB-B4) Managed Care - January 2009 - Impact of RSV: Implications for Managed Care (Page CB-B5) Managed Care - January 2009 - Impact of RSV: Implications for Managed Care (Page CB-B6) Managed Care - January 2009 - Impact of RSV: Implications for Managed Care (Page CB-B7) Managed Care - January 2009 - Impact of RSV: Implications for Managed Care (Page Cover4)
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