Pharmacy & Therapeutics - October 2008 - (Page 562) CONTENTS Cover: Photomicrograph. Lewy body of a pigmented neuron in the substantia nigra from a patient with Parkinson’s disease. Magnification 400x (at 24 x 36 mm). See related article on page 590. (© Pr. J. J. Hauw, ISM / Phototake. All rights reserved.) October 2008 FEATURES COVER STORY Medical Management of Parkinson’s Disease 590 DEPARTMENTS Editorial 566 David Nash, MD, MBA, muses on the gloomy mood of Moody’s Investor Services. Medication Errors 567 Matthew Grissinger, RPh, FASCP, explains how easy it is to misprogram pumps used for patient-controlled analgesia. Prescription: Washington 569 Stephen Barlas discusses the need for Congress to fund a program to evaluate the cost effectiveness of drugs and medical devices. New Drugs/Drug News/ New Medical Devices 570 From Altace to Zyprexa, P&T presents the latest studies and information about FDA approvals, new indications, product recalls, and industry updates. Drug Forecast 574 Dr. Erowele reviews alvimopan, a mu-opioid receptor antagonist (Entereg), for postoperative ileus. A comprehensive discussion of the causes, epidemiology, diagnosis, symptoms, and pharmacotherapy for this movement disorder is presented, with an emphasis on the efficacy and adverse effects of pharmaceutical treatments. Marvin M. Goldenberg, PhD, RPh, MS HEALTH CARE AND LAW Why Is Health Care Regulation So Complex? Although the intricacies of health care regulation may seem inefficient and unwieldy, our system of local, state, and national checks and balances actually makes a certain amount of sense. Dr. Field discusses the logic behind the complexities of the present regulatory system. Robert I. Field, JD, MPH, PhD COMMENTARY 607 The Next President’s Prescription for Action on Drugs Obama and McCain Positions Similar—with One Major Difference The outlook for Medicare Part D and universal health insurance coverage may depend, in part, on who is elected President and how Congress decides to act. Stephen Barlas P&T SNAPSHOT 609 Trends in Managing Multiple Sclerosis The Multiple Sclerosis Trend Report reveals the need for many improvements in treating this expensive and complex disease, such as containing costs of biotech drugs, easing the process of obtaining patient reimbursements and physician payments, developing a role for specialty pharmacy, and eliminating barriers to patient–pharmacy communication. Mari Edlin and Peter Sonnenreich, MA SECTION TWO 611 Product Profiler: Sancuso® (Granisetron Transdermal Delivery System) 562 P&T® • October 2008 • Vol. 33 No. 10
Table of Contents Feed for the Digital Edition of Pharmacy & Therapeutics - October 2008 Pharmacy & Therapeutics - October 2008 Contents Editorial Medication Errors Prescription: Washington New Drugs/Drug News/ New Medical Devices Drug Forecast Medical Management of Parkinson’s Disease Why Is Health Care Regulation So Complex? The Next President’s Prescription for Action on Drugs Trends in Managing Multiple Sclerosis Product Profiler: Sancuso® Pharmacy & Therapeutics - October 2008 Pharmacy & Therapeutics - October 2008 - Pharmacy & Therapeutics - October 2008 (Page Cover1) Pharmacy & Therapeutics - October 2008 - Pharmacy & Therapeutics - October 2008 (Page Welcome) Pharmacy & Therapeutics - October 2008 - Pharmacy & Therapeutics - October 2008 (Page 555) Pharmacy & Therapeutics - October 2008 - Pharmacy & Therapeutics - October 2008 (Page 556) Pharmacy & Therapeutics - October 2008 - Pharmacy & Therapeutics - October 2008 (Page 557) Pharmacy & Therapeutics - October 2008 - Pharmacy & Therapeutics - October 2008 (Page 558) Pharmacy & Therapeutics - October 2008 - Pharmacy & Therapeutics - October 2008 (Page 559) Pharmacy & Therapeutics - October 2008 - Pharmacy & Therapeutics - October 2008 (Page 560) Pharmacy & Therapeutics - October 2008 - Pharmacy & Therapeutics - October 2008 (Page 561) Pharmacy & Therapeutics - October 2008 - Contents (Page 562) Pharmacy & Therapeutics - October 2008 - Contents (Page 563) Pharmacy & Therapeutics - October 2008 - Contents (Page 564) Pharmacy & Therapeutics - October 2008 - Contents (Page 565) Pharmacy & Therapeutics - October 2008 - Editorial (Page 566) Pharmacy & Therapeutics - October 2008 - Medication Errors (Page 567) Pharmacy & Therapeutics - October 2008 - Medication Errors (Page 568) Pharmacy & Therapeutics - October 2008 - Prescription: Washington (Page 569) Pharmacy & Therapeutics - October 2008 - New Drugs/Drug News/ New Medical Devices (Page 570) Pharmacy & Therapeutics - October 2008 - New Drugs/Drug News/ New Medical Devices (Page 571) Pharmacy & Therapeutics - October 2008 - New Drugs/Drug News/ New Medical Devices (Page 572) Pharmacy & Therapeutics - October 2008 - New Drugs/Drug News/ New Medical Devices (Page 573) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 574) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 575) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 576) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 577) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 578) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 579) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 580) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 581) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 582) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 583) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 584) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 585) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 586) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 587) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 588) Pharmacy & Therapeutics - October 2008 - Drug Forecast (Page 589) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 590) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 591) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 592) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 593) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 594) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 595) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 596) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 597) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 598) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 599) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 600) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 601) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 602) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 603) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 604) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 605) Pharmacy & Therapeutics - October 2008 - Medical Management of Parkinson’s Disease (Page 606) Pharmacy & Therapeutics - October 2008 - Why Is Health Care Regulation So Complex? (Page 607) Pharmacy & Therapeutics - October 2008 - Why Is Health Care Regulation So Complex? (Page 608) Pharmacy & Therapeutics - October 2008 - The Next President’s Prescription for Action on Drugs (Page 609) Pharmacy & Therapeutics - October 2008 - The Next President’s Prescription for Action on Drugs (Page 610) Pharmacy & Therapeutics - October 2008 - Trends in Managing Multiple Sclerosis (Page 611) Pharmacy & Therapeutics - October 2008 - Trends in Managing Multiple Sclerosis (Page 612) Pharmacy & Therapeutics - October 2008 - Trends in Managing Multiple Sclerosis (Page 613) Pharmacy & Therapeutics - October 2008 - Trends in Managing Multiple Sclerosis (Page 614) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PPCover1) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PPCover2) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP1) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP2) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP3) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP4) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP5) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP6) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP7) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP8) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP9) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP10) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP11) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP12) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP13) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP14) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP15) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP16) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP17) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP18) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP19) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP20) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP21) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP22) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP23) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP24) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP25) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP26) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP27) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP28) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page PP29) Pharmacy & Therapeutics - October 2008 - Product Profiler: Sancuso® (Page Cover4)
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