Reviews for Primary Care - Fall 2007 - (Page 29) Chronic Constipation and Functional Bowel Disorders 55. 56. 57. 58. 59. 60. Camilleri M, Bharucha AE, Ueno R, et al. Effect of a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory, and motor functions in healthy volunteers. Am J Physiol Gastrointest Liver Physiol. 2006;290:G942-G947. Johanson JF, Gargano MA, Holland PC, Patchen ML. Initial and sustained effects of lubiprostone, a chloride channel-2 (ClC-2) activator for the treatment of constipation: data from a 4-week phase III study [abstract]. Am J Gastroenterol. 2005;100(suppl 9):S324. Johanson JF, Gargano MA, Holland PC, et al. Phase III safety and efficacy of RU-0211, a chloride channel activator, for the treatment of constipation [abstract]. Gastroenterology. 2003;124 (4 suppl 1):A-48. Ueno R, Wahle A, Panas R, et al. Evaluation of safety and efficacy in a twelve-month study of lubiprostone for the treatment of chronic idiopathic constipation [abstract]. Am J Gastroenterol. 2006;101(suppl 2):S491. Crowell MD, Harris LA, DiBlaise JK, Olden KW. Activation of type-2 chloride channels: a novel therapeutic target for the treatment of chronic constipation. Curr Opin Investig Drugs. 2007; 8:66-70. Sucampo Pharmaceuticals submits supplemental new drug application for lubiprostone to treat irritable bowel syndrome with constipation. Sucampo Pharmaceuticals Web site. http:// investor.sucampo.com/phoenix.zhtml?c=201197 &p=irol-newsArticle&ID=1032666&highlight=. Published July 12, 2007. Accessed August 9, 2007. 61. 62. 63. 64. 65. 66. 67. Drossman DA, Chey W, Panas R, et al. Lubiprostone significantly improves symptom relief rates in adults with irritable bowel syndrome and constipation (IBS-C): data from two twelve-week, randomized, placebo-controlled, double-blind trials [abstract]. Gastroenterology. 2007;132: 2586-2587. Heymen S, Scarlett Y, Jones K, et al. Randomized, controlled trial shows biofeedback to be superior to alternative treatments for patients with pelvic floor dyssynergia-type constipation. Dis Colon Rectum. 2007;50:428-441. Chiarioni G, Whitehead WE, Pezza V, et al. Biofeedback is superior to laxatives for normal transit constipation due to pelvic floor dyssynergia. Gastroenterology. 2006;130:657-664. Johanson JF, Panas R, Holland PC, Ueno R. A dose-ranging, double-blind, placebo-controlled study of lubiprostone in subjects with irritable bowel syndrome and constipation (c-IBS) [abstract]. Gastroenterology. 2006;130(4 suppl 2): A-25. Prather CM. Pregnancy-related constipation. Curr Gastroenterol Rep. 2004;6:402-404. Becker D, Compagnone D, Lu L. Lactulose in the treatment of constipation in pregnant Chinese women: a double-blind, randomized, placebocontrolled, multicenter study [abstract]. Gastroenterology. 2006;130(4 suppl 2):A-599-A-600. Engelke K, Harris S, Roerig B, Ueno R. Effect of lubiprostone, a novel type-2 chloride channel (Clc-2) activator, in pregnant rhesus monkeys [abstract]. Gastroenterology. 2007;132(4 suppl 2): A-534. 68. DiPalma JA, Cleveland MV, McGowan J, Herrera JL. An open-label study of chronic polyethylene glycol laxative use in chronic constipation. Aliment Pharmacol Ther. 2007;25:703708. 69. Ueno R, Joswick TR, Wahle A, et al. Efficacy and safety of lubiprostone for the treatment of chronic constipation in elderly vs non-elderly subjects [abstract]. Gastroenterology. 2006;130(4 suppl 2):A-189. 70. Ueno R, Joswick TR, Wahle A, et al. Efficacy and safety of lubiprostone for the treatment of chronic idiopathic constipation in elderly patients. Paper presented at: 71st Annual Scientific Meeting and Postgraduate Course of the American College of Gastroenterology; October 20-25, 2006; Las Vegas, NV. 71. Rivera E, Wahle A, Joswick TR, Ueno R. Lubiprostone, a novel type-2 chloride channel (ClC-2) activator, does not affect serum electrolyte balance in elderly and non-elderly patients with chronic idiopathic constipation [abstract]. Gastroenterology. 2007;132(4 suppl 2): A-191. 72. Corman ML. Colon and Rectal Surgery. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2004. 73. Zutshi M, Hull TL, Trzcinski R, et al. Surgery for slow transit constipation: are we helping patients? Int J Colorectal Dis. 2007;22:265-269. 74. Treatment of pelvic floor dysfunction. Mayo Clinic Web site. http://www.mayoclinic.org/ constipation/treatment-pelvic-floor-dysfunction. html. Accessed August 9, 2007. To receive credit for this CME/CPE/CE activity, please visit http://www.totalmeded.com/ddwmonograph. VOL. 1 NO. 1 2007 REVIEWS FOR PRIMARY CARE 29 http://investor.sucampo.com/phoenix.zhtml?c=201197&p=irol-newsArticle&ID=1032666&highlight= http://investor.sucampo.com/phoenix.zhtml?c=201197&p=irol-newsArticle&ID=1032666&highlight= http://www.mayoclinic.org/constipation/treatment-pelvic-floor-dysfunction.html http://investor.sucampo.com/phoenix.zhtml?c=201197&p=irol-newsArticle&ID=1032666&highlight= http://www.mayoclinic.org/constipation/treatment-pelvic-floor-dysfunction.html http://www.mayoclinic.org/constipation/treatment-pelvic-floor-dysfunction.html http://www.totalmeded.com/ddwmonograph
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