Phenomenex Catalog International 2009 - (Page 10) Sample Preparation Products Phenomenex Offers High Quality Sample Preparation Products • Concentrate, Cleanup, and /or Solvent Switch Quickly and Easily • Eliminate Contaminants and Matrix Effects for Superior Signal to Noise Ratios and Longer Column Lifetimes SAMPLE PREPARATION/SPE • Complete Technical Support and Method Development Assistance • Extensive QC/QA Process Guarantees Quality, Performance, Satisfaction, and Reproducibility If Strata SPE products do not perform as well or better than your current SPE product of similar phase, mass and size, send in your comparative data within 45 days and keep the Strata SPE product for FREE! Solid Phase Extraction (SPE) Advantages • Superior cleanup, concentration, and solvent switching • Superior selectivity and signal-to-noise ratios • Easily automated Disadvantages • Screening different sorbents • Method development time SAMPLE PREPARATION PRODUCTS | Large Volume Cleanup / Flash Analysis Advantages Disadvantages • Desalt and/or concentrate rapidly • Relative cost • Fast purification of mg to multi-gram quantities of analytes • Concentrate 10 mL – 1 L of sample to a few mLs at once Selectivity Liquid-Liquid Extraction - High-Throughput Sample Prep Advantages Disadvantages • Requires automation for high-throughput • Relatively inexpensive • • Inexpensive hardware required • Lengthy method development • Labor intensive • Large volumes of solvent used • Limited separation possibilities Protein Precipitation (PPT) - High-Throughput Sample Prep Advantages Disadvantages • Increase recovery, reproducibility, and column lifetime • Superior removal of proteins and macromolecules • Reduce or eliminate protein-analyte non-specific binding • Generally less selective • Concentration requires evaporation of filtrate Filtration - High-Throughput Sample Prep Advantages Disadvantages • Mechanical filtration of undissolved particulates down to 0.2 µm • Fast, simple, and quick • Non-specific • Further sample preparation may be required for optimal results 10 Phenomenex http://www.phenomenex.com/landing.aspx?=11425 http://www.phenomenex.com/landing.aspx?=11427
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