Phenomenex Catalog International 2009 - (Page 12) Solid Phase Extraction (SPE) Phase Descriptions Phase Reversed Phase C18-E C18-U C18-T (wide pore) C8 Phenyl CN SDB-L (styrene-divinylbenzene) Strata-X* Strata-XL Phase Description Silica-based trifunctional C18 with hydrophobic endcapping of silanols Silica-based trifunctional C18 without endcapping for additional polar silanol interaction Silica-based trifunctional C18 with hydrophobic endcapping of silanols and large pore size Silica-based trifunctional C8 with hydrophobic endcapping of silanols Silica-based trifunctional phenyl with hydrophobic endcapping of silanols Silica-based trifunctional cyano without endcapping for additional polar silanol interaction Polymeric styrene-divinylbenzene resin with larger particle size and pore size Polymeric sorbent with strong pi-pi retention mechanism High capacity large polymeric particle designed to be used for viscous samples Silica-based trifunctional carboxylic acid without endcapping Silica-based trifunctional benzene sulfonic acid without endcapping Proprietary blend of silica-based trifunctional C8 and trifunctional benzene sulfonic acid Polymeric sorbent with strong cation exchange mechanism results in strong retention for basic compounds Polymeric sorbent with weak cation exchange mechanism allows for elution at high and low pH High capacity large polymeric particle designed to be used for viscous samples Silica-based trifunctional amino ligand without endcapping Silica-based trifunctional quaternary amine without endcapping Proprietary blend of silica-based trifunctional C8 and trifunctional quaternary amine Proprietary blend of silica-based trifunctional benzene sulfonic acid and trifunctional amino ligand without endcapping Polymeric sorbent with weak anion exchange mechanism allows for elution at high and low pH Silica-based trifunctional cyano without endcapping for additional polar silanol interaction Silica-based trifunctional amino ligand without endcapping for additional polar silanol interaction Specialty large particle silica with proprietary features Unfunctionalized irregular-shaped high-grade silica with high-purity High-grade large particle magnesium silicate with high-purity Neutral high-grade irregular-shaped Alumina with high-purity Proprietary normal phase sorbent bed topped with sodium sulfate Benefit Extraction of hydrophobic molecules from aqueous and biological samples Increased extraction efficiency and enhanced cleanup of hydrophobic compounds that contain hydroxy or amine functional groups from water or biological fluids Extraction of large hydrophobic molecules (up to 75 kD) from water or biological matrices Extraction of hydrophobic compounds from water or biological fluids that are retained too strongly on Strata C18-E or Strata-X Extraction of aromatic hydrophobic compounds Extraction of non-polar, compounds that are retained too strongly on Strata C18-E or C8 Extraction of non-polar and polar molecules Extract polar and non-polar compounds by reversed phase Extract polar and non-polar compounds from viscous sample matrices or gravity flow Extraction of quaternary amines Extraction of 1°, 2° and 3° amines from biological fluids Extraction of basic drugs from biological matrices such as blood, serum and urine Extract basic compounds by mixed-mode strong cation exchange, pH stable 1-14 Extract bases by mixed-mode weak cation exchange, pH stable 1-14 Extract basic compounds from viscous sample matrices or gravity flow, pH stable 1-14 Extraction of strong and/or weak anions from aqueous solvent Extraction of organic acids Extraction of acidic drugs from biological matrices such as blood, serum and urine Fractionation of neutral compounds such as amides from acidic and basic analytes Extract acids by mixed-mode weak anion exchange, pH stable 1-14 SAMPLE PREPARATION/SPE Cation Exchange WCX (weak cation exchange) SCX (strong cation exchange) Screen-C (mixed-mode cation exchange) Strata-X-C Strata-X-CW Strata-XL-C SOLID PHASE EXTRACTION (SPE) | Anion Exchange WAX / NH2 (weak anion exchange) SAX (strong anion exchange) Screen-A (mixed-mode anion exchange) ABW (specialty phase) Strata-X-AW Normal Phase CN NH2 EPH (Extractable Petroleum Hydrocarbon) Silica (Si-1) Florisil® (FL-PR) Alumina-N (AL-N) Eco-Screen *Strata-X is patented by Phenomenex, Inc. Normal phase sorbent that can effectively extract polar compounds from nonpolar solvents or organic mixtures Extraction of strong anions from aqueous samples or polars in organic mixtures Fractionation of aliphatic and aromatic extractable hydrocarbons from soil and water samples in organic mixtures Extraction of polar compounds that are similar in structure in organic mixtures Extraction of pesticides from environmental samples in organic mixtures Extraction of polar compounds from food and environmental samples in organic mixtures Extraction of naphthalene from environmental samples in organic mixtures For Sample Preparation Quick Reference Charts, see p. 35 For phase structures, turn to the phase product pages, found on pp. 16 to 29. 12 Phenomenex
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