Phenomenex Catalog International 2009 - (Page 24) Strata -X* Polymeric (SPE) Sorbents ™ Strata-X* Polymeric Solid Phase Extraction (SPE) Sorbents • De-conditioning resistant surface resists dry out and de-activation and provides worry-free manual and automated processing • pH stability from 1-14 for flexible method development SAMPLE PREPARATION/SPE • 800 m2/g surface area and high analyte capacity results in the ability to load up to 66 % more in comparison to silica-based sorbents per gram • Grafted polymeric surface offers even distribution of functional groups ensuring excellent lot-to-lot reproducibility Most traditional solid phase extraction sorbents on the market are just variations of the same technology, and often result in poor analyte recoveries, insufficient cleanup, or irreproducibility from extraction-to-extraction. With this in mind, Phenomenex set out to develop a SPE sorbent that exceeded the limitations of traditional SPE sorbents and offered increased speed, simplicity, and reproducibility for sample preparation. Utilizing a controlled manufacturing process and rigorous performance specifications we are pleased to bring you Strata-X polymeric sorbents, a line of polymeric SPE sorbents that allows for a simplified approach to solid phase extraction. High Recoveries of Acidic, Basic, and Neutral Compounds Nordoxepin Amitriptyline Nortriptyline Doxepin Procainamide Cimetidine 0 20 40 60 80 100 0 If Strata SPE products do not perform as well or better than your current SPE product of similar phase, mass and size, send in your comparative data within 45 days and keep the Strata SPE product for FREE! STRATA-X POLyMERIC (SPE) SORBENTS | Conditions Acetaminophen Theobromine Theophylline Caffeine 20 40 60 80 100 0 Ibuprofen Naproxen Fenoprofen Indomethacin 20 40 60 80 100 Bases Neutrals Acids Method: Analytes spiked in porcine serum at concentration of 0.5 or 1.0 μg/mL. The Strata-X method was used. Contact Phenomenex for more complete method details. % Recovery % Recovery % Recovery Strata-X 96-Well Plates Automated SPE Extraction 0.50 Human Urine over 100 Fold conc. range Calibration curve of Atenolol FREE 96-Well Plate Method Development White Paper 100 0.40 Analyte Area / IS Area 0.30 % Recovery 80 60 40 0.24 µg/mL 20 0 24 µg/mL 22 24 0.20 0.10 Concentration 20 0 0 2 4 6 8 10 12 14 µg (conc) 16 18 Part No.: 4567_L SPE Conditions Sorbent: Part No.: Processing station: Condition: Equilibrate: Load: Wash 1: Wash 2: Elute: Elution: 30 mg Strata-X 96-well plate 8E-S100-TGB PerkinElmer MultiPROBE® II 40 μL Methanol 400 μL Water 500 μL urine diluted with 1mL water 1 mL 5 % methanol in water 800 μL 30 % Methanol/Water 800 μL water 400 μL methanol (in two aliquots) HPLC Column: Dimension: Part No.: Mobile Phase: Gemini® 3 μm C18 50 x 2.0 mm 00B-4439-B0 0.1 % Formic Acid in Water/ 0.1 % Formic Acid in Acetonitrile (70:30) Flow Rate: 1 mL/min Temperature: Ambient Detector: ESI+ * Strata-X is patented by Phenomenex, Inc. Strata-X is a trademark of Phenomenex, Inc. 24 Phenomenex http://www.phenomenex.com/lib/4567.pdf
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