Chemical Processing - October 2007 - (Page 40)

Shaft Alignment Rotalign® ULTRA OPTALIGN® smart are single-use, permitting their disposal after each batch and their replacement with a new system. Of course mixers — and other single-use equipment — need to be connected with each other and with the rest of the process. Ensuring the sterility of this step was once a major headache for disposables’ suppliers. Now, however, such integration is routine thanks to developments in connection hardware. Take, for example, the latest additions to the Steam-Thru series from Colder, St. Paul, Minn. An innovative design allows quick and easy sterile connection between biopharmaceutical processing equipment and disposable bag and tube assemblies. Media can be safely transferred without the cleaning and validation concerns associated with reusable components (Figure 2). Combine the ability to link singleuse equipment in a safe and efficient manner with takeovers that expand process know-how at vendors and you begin to wonder how far away we are from a whole disposable process. This isn’t a pipedream. A process-in-a-box? Pall has been in the disposables business for ages, and its recent product introductions and business expansion plans clearly are pointing in one direction: the process-in-a-box. Already this year the company has launched its SupraCap 100 depth filter capsule, marketing it as the only intermediate-scale depth filter to be offered in a range of sizes, styles and configurations (Figure 3). The capsule provides the usual features of disposables, but also a lower hold-up volume than standard module housings. This both speeds up and increases product recovery in the 5–100-L applications that are typical of pilot-scale operations as well as clinical batches and personalized medicines. In an important hint at the shape of things to come, these capsules >> Sterile connection Figure 2. Devices such as these ensure quick and easy connections between system components. Source: Colder. h Watc O IDE e Vn Onli ALIGNEO® The right tool for every user, job and budget 305-591-8935 • www.ludeca.com can be manifolded together or connected upstream of the company’s KleenPak Nova filters as a fully-integrated disposable system that reportedly offers higher performance in a smaller footprint and increased production with minimal revalidation (Figure 4). “This new intermediate-scale capsule complements Pall’s line of SupraCap depth filters and provides a critical scale-up path for process developers,” says Scott Anderson, global product manager for Pall Life Sciences. “Providing a critical link between discovery and production processes, the SupraCap 100 depth filter capsule enables process developers to begin testing at the earliest development stage to maximize their investment.” This year the company also introduced an innovation in biocontainers, which are an integral component of single-use processing for collecting and transporting process www.chemicalprocessing.com http://www.ludeca.com http://www.ludeca.com http://www.chemicalprocessing.com

Table of Contents Feed for the Digital Edition of Chemical Processing - October 2007

Chemical Processing - October 2007 Contents From the Editor ChemicalProcessing.com Field Notes In Process Energy Saver Compliance Advisor Biofeedstocks See Real Growth Become a Cyber-Security Pacesetter Go Beyond Condition Monitoring Disposable Equipment Earns Lasting Role Improve Control Loop Performance Ethanol Plant Boosts Output and Saves Energy Process Puzzler Plant InSites Equipment & Services Ad Lits Product Spotlight/Classifieds Ad Index End Point

Chemical Processing - October 2007

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