Chemical Processing - October 2007 - (Page 44)

torius Biotech Division. “This transaction significantly accelerates our strategy to offer customers fully integrated solutions for next generation biopharmaceutical manufacturing,” he says. The new company, Sartorius Stedim Biotech offers fluid management, purification, filtration (Figure 6) and fermentation — in fact the sort of comprehensive range of biotechnologies and services needed for future entirely disposable processes. A user’s perspective Clearly single-use equipment is gaining increasing acceptance. Lilly provides an illuminating example of a leading manufacturer’s approach to disposables. The company uses disposable bioreactors, buffers/medias, sample bags and connectors, plus more specialized technology such as tangential flow filtration (TFF) and nanofiltration. “In terms of the suppliers, our big issue is delivery time,” explains Bailey. “When we need something, we usually need it very quickly. For example, we might be making product ‘A’ today, but things change and we need to move to product ‘B’ very quickly. Therefore lead times are the biggest issue.” Lilly encountererd what Bailey describes as “one of the growing pains of using disposables.” At one point, he 9/26/07 12:05 AM Page 1 TLCTCO Ad Chem Process urgently needed a very specific tubing set. While two suppliers had the tubing in stock, the disposable connectors required would take 12 weeks to arrive from its manufacturer. “We have now worked this through with our suppliers to identify the longer-term supply items and make sure that they always have them in stock for us.” This close working with the suppliers also is important to Lilly in terms of technological innovation. For example, when the company first attempted to source a disposable TFF unit, no supplier could help. However, Millipore later came on board and together the companies developed the required unit. “Working with suppliers has proved to be the way forward and we are now working with a number of vendors in order to get exactly what we need,” says Bailey. While Bailey can understand the process-in-a-box vision of some suppliers, he points to an ongoing challenge — purification . “In terms of the future, one issue for Lilly is membrane adsorbers. We are working in a consortium to understand exactly how they work because membrane adsorbers have the potential to become a key part of our purification process. Also, it would be great is someone could really figure out a method of making disposable on/off chromatography possible,” he concludes. CP Flexible Components Proudly Presents ® TLCTCO Chemfluor FEP Rubber Hose TLCT rubber hose has been a staple in process industries for many years. Our TLCTCO hose takes it to the next level, with an externally convoluted EPDM outer cover for improved flexibility. TLCTCO has all the features that make TLCT so popular: high purity, ultra-smooth Chemfluor® FEP fluoropolymer liner, durability and ease of handling, and compliance with all key industry sanitary standards. It’s ideal for many critical applications, including chemical process lines, transfer lines, rail car loading/unloading, and skid, vessel and tank transfers. TLCTCO is a proven, reliable product that we are confident will deliver improved productivity, greater ease of handling and better value. Features/Benefits • Reduced force-to-bend • Improved bend radius • Ultra-flexibility • Easy to handle • Smooth ID when bent • High pressure rating • Kink resistant • Sterilizable and autoclavable • Imparts no taste or odor • Non-aging liner • Ozone and abrasion resistant cover Saint-Gobain Performance Plastics 460 Milltown Road Bridgewater, NJ 08807 800-435-3992 www.flexiblecomponents.com TWOY Flexible Components offers many other hose and fitting products, including: WTLCTPFA TS TLCT BCS Please visit us at Chem Show in New York 10/30–11/1, booth #1331. Chemfluor® is a Saint-Gobain Performance Plastics registered trademark. FLS-FC2-0907-SGCS MTLSJ 44 • October 2007 www.chemicalprocessing.com http://www.flexiblecomponents.com http://www.flexiblecomponents.com http://www.chemicalprocessing.com

Table of Contents Feed for the Digital Edition of Chemical Processing - October 2007

Chemical Processing - October 2007 Contents From the Editor ChemicalProcessing.com Field Notes In Process Energy Saver Compliance Advisor Biofeedstocks See Real Growth Become a Cyber-Security Pacesetter Go Beyond Condition Monitoring Disposable Equipment Earns Lasting Role Improve Control Loop Performance Ethanol Plant Boosts Output and Saves Energy Process Puzzler Plant InSites Equipment & Services Ad Lits Product Spotlight/Classifieds Ad Index End Point

Chemical Processing - October 2007

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