Hospital Pharmacy - May 2017 - 361

715364
research-article2017

HPXXXX10.1177/0018578717715364Hospital PharmacySaid and Hussain

Article

Adverse Drug Reaction Reporting
Practices Among United Arab Emirates
Pharmacists and Prescribers

Hospital Pharmacy
2017, Vol. 52(5) 361-366
© The Author(s) 2017
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https://doi.org/10.1177/0018578717715364
DOI: 10.1177/0018578717715364
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Amira S. A. Said1 and Nadia Hussain1

Abstract
Background: Underreporting of adverse drug reactions (ADRs) has placed a heavy financial burden on health care
resources worldwide. Realizing the importance of proper ADR reporting is paramount for implementing better patient care.
Objective: This study was designed to assess knowledge, attitude, and practice (KAP) of ADR reporting among United
Arab Emirates (UAE) health care professionals to clarify their present strategies and identify steps to avoid underreporting.
Methods: A self-administered cross-sectional questionnaire was designed and randomly distributed to different health
care personnel (n = 150). All participants were briefly informed about the aim of the study and given sufficient time to
respond. The responses were collected over 6 months. The data were statistically analyzed for each reporter category
(community pharmacist, hospital pharmacist, and doctors) using the chi-square test. Results: We found that 81%, 83%,
and 83.3% of doctors, community pharmacists, and hospital pharmacists, respectively, were not aware of the existence of
a reporting center and 56%, 60%, and 72% were not aware of a reporting procedure. Poor ADR reporting practices were
shown by responders; only 19%, 14%, and 12.1% of doctors, community pharmacists, and hospital pharmacists reported
ADRs. Conclusion: This study showed poor KAP results among health care professionals. Proper educational intervention
strategies should be established in different health care settings for better patient care. With proper guidance, objectives in
all health care settings should be targeted to positively change the concept of health care to consider ADR reporting as a
common accepted daily routine practice.
Keywords
adverse drug reactions, attitude, community pharmacists, hospital pharmacists, knowledge, pharmacovigilance, practice
According to the World Health Organization (WHO) definition, an adverse drug reaction (ADR) is any noxious,
unintended, and undesired effect of a drug, which occurs at
doses used in humans for prophylaxis, diagnosis, or therapy.1 This description highlights the importance of the roles
played by individual patient responses in determining an
ADR. The use of any medication can create unwanted consequences. As stated by the Center for Health Policy
Research, more than 50% of approved drugs in the United
States are associated with some type of an adverse effect
that was not detected prior to approval.1 At this point, the
role of pharmacovigilance in addressing drug safety issues
becomes crucial.
Pharmacovigilance is defined as "the science and the
activities which relate to the detection, assessment, understanding and the prevention of adverse effects or any other
drug-related problems."2(p7) Good pharmacovigilance programs are an effective means to identify risks in the shortest
possible time so that harm can be avoided or minimized. A
proper spontaneous ADR reporting system is the basis for
sound and comprehensive postmarketing surveillance drug

studies. These studies compensate for any inadequacy in drug
safety data resulting from the many limitations of premarketing clinical trials.2,3
The WHO has recommended that every country initiate
pharmacovigilance programs to identify drugs that cause
ADRs.1,4 However, underreporting of ADRs in various health
care settings still represents a considerable challenge that
needs to be faced, especially in developed countries.1 The
significant impact of ADR reporting by health care workers
on establishing an effective worldwide ADR database has
been emphasized in several previous studies.5,6 The presence
of ADRs is an important public health issue that has a significant impact on patient morbidity and mortality and has
caused up to 11% of hospital admissions.7-9 A previous
1

Al Ain University of Science and Technology, United Arab Emirates

Corresponding Author:
Nadia Hussain, Faculty of Pharmacy, Department of Pharmaceutical
Sciences, Al Ain University of Science and Technology, PO Box 64141,
Al Ain, United Arab Emirates.
Email: nadia.hussain@aau.ac.ae


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Table of Contents for the Digital Edition of Hospital Pharmacy - May 2017

Editorial, For Sale: FDA Priority Review Vouchers
Current FDA-Related Drug Information; Approvals, Submission, and Important Labeling Changes for US Marketed Pharmaceuticals
Summaries of Safety Labeling Changes Approved by the FDA: Boxed Warnings
ISMP Adverse Drug Reactions: Levofloxacin-Induced Neuroexcitation and Hallucinations Statin-Induced Muscle Rupture Mefloquine-Induced Rhabdomyolysis Methimazole-Induced
Critical Care Pharmacist Market Perceptions: Comparison of Critical Care Program Directors and Directors of Pharmacy
Capecitabine, Oxaliplatin, and Bevacizumab (BCapOx) Regimen for Metastatic Colorectal Cancer
Clinical Pharmacy Discharge Counseling Service and the Impact on Readmission Rates in High-Risk Patients
Mannitol Prescribing Practices With Cisplatin Before and After an Educational Newsletter Intervention
Pharmacists’ Knowledge of the Cost of Laboratory Testing
Adverse Drug Reaction Reporting Practices Among United Arab Emirates Pharmacists and Prescribers
Postoperative Pain Management With Liposomal Bupivacaine in Patients Undergoing Orthopedic Knee and Hip Arthroplasty at a Community Hospital
Formulary Drug Reviews
Hospital Pharmacy - May 2017 - 317
Hospital Pharmacy - May 2017 - 318
Hospital Pharmacy - May 2017 - 319
Hospital Pharmacy - May 2017 - 320
Hospital Pharmacy - May 2017 - 321
Hospital Pharmacy - May 2017 - 322
Hospital Pharmacy - May 2017 - 323
Hospital Pharmacy - May 2017 - Editorial, For Sale: FDA Priority Review Vouchers
Hospital Pharmacy - May 2017 - 325
Hospital Pharmacy - May 2017 - Current FDA-Related Drug Information; Approvals, Submission, and Important Labeling Changes for US Marketed Pharmaceuticals
Hospital Pharmacy - May 2017 - Summaries of Safety Labeling Changes Approved by the FDA: Boxed Warnings
Hospital Pharmacy - May 2017 - 328
Hospital Pharmacy - May 2017 - 329
Hospital Pharmacy - May 2017 - ISMP Adverse Drug Reactions: Levofloxacin-Induced Neuroexcitation and Hallucinations Statin-Induced Muscle Rupture Mefloquine-Induced Rhabdomyolysis Methimazole-Induced
Hospital Pharmacy - May 2017 - 331
Hospital Pharmacy - May 2017 - 332
Hospital Pharmacy - May 2017 - 333
Hospital Pharmacy - May 2017 - Critical Care Pharmacist Market Perceptions: Comparison of Critical Care Program Directors and Directors of Pharmacy
Hospital Pharmacy - May 2017 - 335
Hospital Pharmacy - May 2017 - 336
Hospital Pharmacy - May 2017 - 337
Hospital Pharmacy - May 2017 - 338
Hospital Pharmacy - May 2017 - 339
Hospital Pharmacy - May 2017 - 340
Hospital Pharmacy - May 2017 - Capecitabine, Oxaliplatin, and Bevacizumab (BCapOx) Regimen for Metastatic Colorectal Cancer
Hospital Pharmacy - May 2017 - 342
Hospital Pharmacy - May 2017 - 343
Hospital Pharmacy - May 2017 - 344
Hospital Pharmacy - May 2017 - 345
Hospital Pharmacy - May 2017 - 346
Hospital Pharmacy - May 2017 - 347
Hospital Pharmacy - May 2017 - Clinical Pharmacy Discharge Counseling Service and the Impact on Readmission Rates in High-Risk Patients
Hospital Pharmacy - May 2017 - 349
Hospital Pharmacy - May 2017 - 350
Hospital Pharmacy - May 2017 - 351
Hospital Pharmacy - May 2017 - 352
Hospital Pharmacy - May 2017 - Mannitol Prescribing Practices With Cisplatin Before and After an Educational Newsletter Intervention
Hospital Pharmacy - May 2017 - 354
Hospital Pharmacy - May 2017 - 355
Hospital Pharmacy - May 2017 - 356
Hospital Pharmacy - May 2017 - Pharmacists’ Knowledge of the Cost of Laboratory Testing
Hospital Pharmacy - May 2017 - 358
Hospital Pharmacy - May 2017 - 359
Hospital Pharmacy - May 2017 - 360
Hospital Pharmacy - May 2017 - Adverse Drug Reaction Reporting Practices Among United Arab Emirates Pharmacists and Prescribers
Hospital Pharmacy - May 2017 - 362
Hospital Pharmacy - May 2017 - 363
Hospital Pharmacy - May 2017 - 364
Hospital Pharmacy - May 2017 - 365
Hospital Pharmacy - May 2017 - 366
Hospital Pharmacy - May 2017 - Postoperative Pain Management With Liposomal Bupivacaine in Patients Undergoing Orthopedic Knee and Hip Arthroplasty at a Community Hospital
Hospital Pharmacy - May 2017 - 368
Hospital Pharmacy - May 2017 - 369
Hospital Pharmacy - May 2017 - 370
Hospital Pharmacy - May 2017 - 371
Hospital Pharmacy - May 2017 - 372
Hospital Pharmacy - May 2017 - 373
Hospital Pharmacy - May 2017 - Formulary Drug Reviews
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Hospital Pharmacy - May 2017 - 376
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Hospital Pharmacy - May 2017 - 379
Hospital Pharmacy - May 2017 - 380
Hospital Pharmacy - May 2017 - 381
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