Shaklee Product Catalogue 2011 - (Page 61)
Proof of the Products
TARGETED NUTRITION
SUBJECT: Vita-C 500 Sustained Release 500 mg Vitamin C Supplement and Vita-C 100 Chewable 100 mg Vitamin C Supplement Clinical Study: Vita-C proven bioavailability This study examined blood vitamin C concentrations for 25 hours following administration of 1,000 mg of vitamin C, taken all at once; 100 mg of vitamin C consumed hourly for 10 hours; and 500 mg of vitamin C in the form of a sustained-release preparation, taken twice at a 5-hour interval. Results showed that the sustained-release preparation produced blood vitamin C levels comparable to consuming 100 mg of vitamin C on an hourly basis. The large-dose immediate-release preparation produced significantly lower blood vitamin C levels over the 25-hour period due to a faster rate of urinary vitamin C excretion.
VITA-C: CLINICALLY TESTED BIOAVAILABILITY
there were no significant changes in markers of renal and liver function or blood chemistries. These findings appear to support recent scientific evidence, which suggests that consumption of additional leucine during a weight-loss diet spares lean tissue. This trial also provides preliminary evidence that adherence to a novel weight-loss program for 12 weeks resulted in effective weight loss and improvements in anthropometric measurements.
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ESTIMATED FAT-FREE MASS VS. TIME
in the laboratory, during which time the cyclists consumed either Shaklee Performance® or water, the speed was turned up even higher. At this sprint pace, Shaklee Performance® drinkers endured for 33 minutes, while the water-only group lasted just two minutes.
References: Wong LG, Jensen CD, Whittam JH. The effects of sodium carbohydrate (Na:Carb) ratios in rehydration beverages (RB) on plasma glucose (PG), osmolality (PO), volume (PV), and subject tolerance (ST). FASEB J 1990;4:A381 (abstr). Yaspelkis III BB, Patterson JG, Anderla PA, Ding Z, Ivy JL. Carbohydrate supplementation spares muscle glycogen during variable intensity exercise. J Appl Physiol 1993;75:1477-85.
PERSONAL CARE
SUBJECT: Enfuselle® Product Line (Global Skin Care Program) The introduction of the Enfuselle® skin care line has been accompanied by extensive clinical testing, outlined below. For more information, contact your Distributor or Sponsor to obtain a copy of this information, or visit Shaklee.com. Some of the Enfuselle® clinical studies utilized contralateral (half-face) studies. Bioinstruments were used to objectively measure the depth of fine lines and wrinkles on one side of the face where Enfuselle® was being applied and compared these results to the control side where no skin care products or makeup were used. The results of the tests, due in part to the rapidly changing climate conditions, were extraordinary: where no skin care or cosmetic products were used, the visible signs of aging became measurably deeper, while the skin treated with Enfuselle® products steadily improved. In addition to bioinstrumentation, subjects completed a detailed questionnaire following the tests subjectively rating the products’ results. SUBJECT: Enfuselle Vital Repair+® Complex: In vitro study of the effectiveness of a unique combination of known antioxidants, Vital Repair+®, in human cell cultures Enfuselle® Vital Repair+® complex: Exhibits significant antioxidant activity in cell cultures of human skin cells exposed to ultraviolet (UV) light. This unique, patented (#6,036,946) combination of ingredients composed of vitamins A, C, and E, along with panthenol, grapeseed extract, superoxide dismutase, and beta glucan, has been shown to protect against cellular death caused by exposure to the UV wavelengths of natural sunlight. The activity of this complex was found to be synergistic, that is, the activity of the complex was much greater than the sum of the activity of the individual components or the sum of the activity of those component materials. The effectiveness of Vital Repair+® complex has been demonstrated in human cell cultures in which free radicals were generated by exposing those cultures to ultraviolet (UV) light. When compared to cell cultures exposed to the same amount of UV light but not treated with Vital Repair+® complex or its component ingredients, the cell cultures treated with Vital Repair+® complex were found to exhibit a significantly lower number of cell deaths. All cell culture measurements were made within 48 hours following exposure of the cell cultures to the UV light. These measurements were run in triplicate for each material tested and were conducted using techniques commonly employed in cell culture technology. The reduction in cell death was accompanied by
105
Fat-Free Mass, Pounds
100.5
100
99.4
95
90
Baseline
Week 2
Week 4
Week 6
Week 8
Week 10
Week 12
MEAN WEIGHT LOSS VS. TIME
190
Vitamin C Concentration (mcg/mL)
24 20 16 12 8 4 0 1 3 5 7 9 13... 25
186.8
185
Weight, Pounds
180
175
Time (Hours)
Shaklee Vita-C 100 Chewable Shaklee Vita-C 500 Sustained Release 1,000 mg Vitamin C Taken at Once
171.4
170
Baseline Week 2 Week 4 Week 6 Week 8 Week 10 Week 12
Reference: Chuck C, Print S, Pattison T, Whittam J, Scala J. Urine and plasma ascorbic acid levels in humans after administration of immediate- and sustained-release ascorbic acid tablets. Data on file, Shaklee Corporation.
SPORTS NUTRITION
SUBJECT: Shaklee Performance® Maximum Endurance Sports Drink Clinical Study: Shaklee Performance®: Effective hydration and more energy Cyclists rode stationary bicycles at 70% VO2 max for two to three hours. Shaklee Performance®, other carbohydrate electrolyte prototypes, and water were given to the athletes at the rate of one litre per hour. Shaklee Performance® maintained blood glucose levels significantly higher than water throughout the test period, while maintaining plasma volume equal to that of water. Shaklee Performance® also maintained a higher plasma osmolality than water, helping balance thirst with fluid needs and supporting the osmotic drive to drink. It was also the best tolerated of all the carbohydrate-electrolyte prototypes.
SHAKLEE PERFORMANCE® OFFERS PROVEN ENDURANCE
Placebo (Flavoured Water)
WEIGHT MANAGEMENT
SUBJECT: Cinch® Inch-Loss Plan Clinical Study: Cinch® 12-week safety and efficacy pilot study This pilot study was designed to determine changes in weight loss, anthropometric measurements, and estimates of body composition in an uncontrolled 12-week trial with 27 moderately overweight but otherwise healthy men and women. Subjects were instructed to consume two Cinch® beverage shakes, three Cinch® dietary supplement tablets, one Cinch® nutrition bar, and a healthy meal and/or snack daily. Eighteen participants, 14 of which were fully compliant, completed the 12-week trial. Data from 14 participants show that subjects lost an average of 15.4 pounds and maintained their fat-free mass based on estimates from skinfold caliper measures. Together, this data suggest that weight loss was derived primarily from body fat, and that fat-free mass was preserved. Waist and hip measurements were reduced by 4.1 and 2.6 inches, respectively, which was a significant reduction in waist-to-hip ratio, a predictor of cardiovascular disease. In addition, favourable changes were observed in blood lipids, including a 10% drop in total cholesterol and a 34% drop in triglycerides. Additionally, no significant adverse events were noted by participants over the 12 weeks, and
200
+
2
Shaklee Performance®
200
33
Minutes Until Fatigue (80% of VO2 max)
Minutes Cycling (45%–75% VO2 max)
Clinical Study: Shaklee Performance®: Maximizing endurance Shaklee Performance® helped maintain athletes’ blood glucose levels for muscle energy and fluid levels for proper hydration. After more than three hours of vigorous cycling
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61
CLINICAL RESEARCH
+
Proof of the Products
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Table of Contents for the Digital Edition of Shaklee Product Catalogue 2011
Shaklee Product Catalogue 2011
Contents
Healthy Nutrition
Healthy Weight
Healthy Home
Healthy Beauty
Clinical Research
Shaklee Product Catalogue 2011
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