ACR/ARHP 2009 Daily News Day 3 - (Page 1) Program Updates Room Change ACR Concurrent Abstracts (#1190-1195), RA: Clinical Aspects/Early Arthritis, will now be held in Grand Ballroom Salon E at the Philadelphia Marriott. Speaker Change Andrew Luster, MD, will present the lecture titled “Molecular Pathways of Fibroblast Recruitment and Activation in Fibrosis” during today’s ACR Basic Science Symposium Fibrosis in Rheumatic Disease: Pathogenenic and Clinical Insights. research indicates that synovial fibroblasts actively drive joint destruction in ra Encore Theater Added: The ACR Concurrent Abstract Session RA Therapy: Biologic Therapy will be shown today from noon – 1:30 pm. Changed: ACR Medical Aspects will be shown from 2:00 – 3:00 pm. Exhibit Hall The correct location for the Amgen Wyeth booth is # 601. over the past decade or so has shown that rheumatoid arthritis synovial fibroblasts play a key role in cartilage and bone destruction in patients with RA. A State-of-the-Art Lecture yesterday explored the latest research, explaining the “Pathogenic Role of Synovial Fibroblasts in Rheumatoid Arthritis.” The lecture was presented by Steffen Gay, MD, Extensive research head of the Center of Extis, as well as his own perimental Rheumatology at lab’s studies of epigenetic the University of Zürich and control of the molecular director of the World Health and cellular basis of joint Organization Collaborating destruction in RA. Center for Molecular BiolWhen activated in ogy and Novel Strategies rheumatoid ar thritis, for the Treatment of RheuRA-SFs increase the matic Diseases in Zürich, expression of adhesion Switzerland. molecules and adhere to Dr. Gay reviewed an acand invade cartilage and cumulating body of research Steffen Gay, MD bone, resulting in joint illustrating that RA-SFs are active drivers destruction, Dr. Gay said. There is also See SynoviaL FiBroBLaStS, page 10 of joint destruction in rheumatoid arthri- InSIdE RCR Interoperability . . . SGR Legislation . . . . . Slide Competition Winners Multidisciplinary Clinics . . Mesenchymal Stem Cells . Updated OA Guidelines . . New ARHP President . . . ARHP General Session . . REF Awards Luncheon . . Hyperuricemia Session . . Thieves Market . . . . . Surviving an Audit . . . . Exhibit Hall Highlights . . Antiphospholipid Syndrome Notable Posters . . . . . Guided Poster Tours . . . MTP & Workshop Tickets . Late-Breaking Abstracts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 . 6 . 6 . 8 . 9 10 14 15 16 17 18 18 18 22 23 23 30 34 Common beliefs about lower back pain questioned YesterdaY afternoon’s aCr Clinical Symposia “Low Back Pain – Clinical Evaluation, Medical, and Surgical Treatment,” began with a show of hands. “How many of you have had lower back pain?” asked Richard Deyo, MD, MPH, the Kaiser-Permanente Endowed Professor of Evidence-Based Medicine in the Department of Family Medicine at Oregon Health and Science University. “Wow, much of the room.” Dr. Deyo then asked how many audience members had lower back pain with sciatica. Many hands went down. Finally, he asked how many have had lower back surgery. Only a few hands remained raised. “Well, there’s our first lesson in epidemiology,” Dr. Deyo said. “It is a ubiquitous problem, but very uncommon for it to require surgery.” Dr. Deyo then outlined common beliefs about back pain that he encountered in medical school: • Primarily a surgical problem • Precise diagnosis can generally be determined • Imaging will usually reveal the cause • It is an injury, which will respond to bed rest • Surgical indications are clear • Prognosis is poor and it may become chronic “I have since found, reviewing the studies over the last 20 years, that these are largely wrong,” he said. “And they need updating.” Dr. Deyo said lower back pain is the most frequently reported reason for visiting a doctor by adults in the U.S. “In the most recent national surveys, about a quarter of Americans report experiencing lower back pain at least one day in the past three months,” he said. However, less than two percent have sciatica. And more importantly, physician visits for back pain have stayed fairly constant since 1990. “So I don’t think we’re See Lower Back Pain, page 4 TAKE THE FIRST STEP TOWARD A NEW RESPONSE. Visit Cypress Bioscience Booth #1039. 30-0007.0 http://www.rheumatology.org/annual/ Table of Contents for the Digital Edition of ACR/ARHP 2009 Daily News Day 3 ACR/ARHP 2009 Daily News Day 3 Contents RCR Interoperability Slide Competition Winners SGR Legislation Multidisciplinary Clinics Mesenchymal Stem Cells Updated OA Guidelines New ARHP President ARHP General Session REF Awards Luncheon Hyperuricemia Session Exhibit Hall Highlights Surviving an Audit Thieves Market Antiphospholipid Syndrome Notable Posters Guided Poster Tours MTP & Workshop Tickets Late-Breaking Abstracts Exhibit Guide ACR/ARHP 2009 Daily News Day 3 http://www.nxtbookMEDIA.com
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