International Stroke Conference 2008 Preview

iSc Preview | New Orleans 9 Relationship between stroke, pregnancy, and ovarian hormones to be discussed pregnancy and the uSe of oral contraceptives and hormone replacement therapy are known stroke risk factors, and stroke is a major contributor to serious morbidity and mortality during pregnancy. To help attendees better understand the relationship between stroke, pregnancy, and ovarian hormones, a special symposium will be held at ISC 2008 titled “Ovarian Hormones, Pregnancy and Stroke: Risks, Management and Prevention.” The symposium will meet from 2:00 to 3:30 p.m. on Wednesday, Feb. 20, in La Louisiane C. “This seminar will update attendees on aspects of cerebrovascular disease as it relates to pregnancy and ovarian hormones. Speakers will discuss management options for clinicians,” said session co-moderator Barney J. Stern, MD, Professor of Neurology and Director of the Clinical Stroke Program at the University of Maryland, Baltimore. “The implications to neurologists of The management issues that need to treating pregnant women is that suddenly you are treating two patients rather than be considered in regard to ischemic stroke one, and clinicians must consider the health include options for primary or secondary of both the mother and the fetus,” Dr. Stern stroke prevention in high-risk patients, continued. “Often, when problems arise, including patients with known cardiac they arise acutely, and so we are trying to disease. Other patients have vascular bring the audience up to date on current anomalies, such as aneurysms or arteriomanagement concepts and key issues re- venous malformations, that predispose to hemorrhagic stroke, Dr. Stern said. lated to decision making.” “The issues related to treatment include Issues relating to birth control pills and hormone replacement therapy as potential the use of thrombolytic therapy in the setstroke risk factors center on their impact on ting of acute ischemic stroke in a pregnant the vasculature and brain, Dr. Stern added. woman and the management of vascular anomalies during preg“Women who have nancy,” he added. migraine with aura and The session’s other who are hypertensive co-moderator, Dilip or smoking are thought K. Pandey, MD, PhD, to be at considerably Associate Professor of increased risk of stroke, Neurology and Director especially when taking of Neuroepidemiology oral contraceptives,” he and Clinical Trials at said. “The issue of postthe University of Illinois menopausal hormone College of Medicine at replacement therapy Chicago, said the symhas been analyzed in posium will also focus severa l studies and on the translational linked to stroke risk.” Dilip K. Pandey, MD, PhD aspects of research into the relationship between endogenous ovarian hormones, hormonal therapy, and the risk of stroke and its management. “There’s lots of confusion in this field at this time,” he said. While the Women’s Health Initiative study has shown that hormone replacement therapy increases the risk of stroke, “studies in animal models have shown a neuroprotective effect. The presenters for this seminar will offer attendees clear direction,” Dr. Pandey said. “This session will be very informative for attendees,” he added. “It will present current knowledge gained from animal models and epidemiologic studies and compare that information to the results of clinical trials. When we look at animal studies, we need to look critically at how the results can be translated safely to clinical care.” Dr. Stern added: “This topic is always anxiety-provoking to patients, their families, and physicians engaged in the care of women at various stages in their life. The issue of hormone use continues to be explored as it relates both to stroke risk and stroke therapy.” chOice continued from page 1 of the research, the experimental model of basic science research and how novel it may be, and the impact of the study—that is, whether we think everybody should hear about it,” he added. The research to be presented in the “Chairs’ Choice I” session icludes: • An international study of stroke prevalence • Research on the diameter of the leftatrium as a predictor of atrial fibrillation in ischemic stroke patients • A study of the ability of the ABCD2 clinical prediction rule to identify patients at low risk for transient ischemic attacks • An abstract looking at the validity of using a nursing swallow screening tool for acute neuroscience patients • Research on neurovascular phenotypes in children with ruptured idiopathic intracranial arterial aneurysms • A study of stroke risk factors as predictors of decline in the absence of clinically diagnosed incident stroke • Research into whether certain genes (MCP-1 and CCR2) act synergistically to increase the risk of carotid atherosclerosis “ My hope is that attendees will hear about this cutting-edge research and take the information back to their practice to improve patient care and research,” Dr. Gorelick said. Unofficial Satellite Events wedneSday, february 20 Symposium 7:30 – 10:00 p.m. “Managing Atherothrombosis in the Stroke Patient: Optimizing Outcomes With Antiplatelet Therapy” Hilton New Orleans Riverside Ballroom A Sponsored by: Bristol-Myers Squibb/ Sanofi-Aventis Supported by: Bristol-Myers Squibb/ Sanofi-Aventis Open to all attendees Symposium 7:30 – 10:00 p.m. “Recurrent Stroke and Intracranial SteClosed (by invitation only)sis: Exploring Treatment Options” Hilton New Orleans Riverside Versailles Ballroom Sponsored by: National Stroke Association Supported by: National Stroke Association Open to all attendees Investigator Meeting 7:30 – 10:00 p.m. “IMS III/MR Rescue InvestigatorCoordinator Meeting” Marriot New Orleans Convention Center Sponsored by: University of Cincinnati Supported by: University of Cincinnati This is an invitation-only event ischemia, pathophysiology and thrombosis, nursing and rehabilitation, outcomes research, pediatric stroke, vascular cognitive impairment, cerebrovascular vessel biology, cranial and spinal vascular malformations, extracranial and intracranial occlusive disease, and ischemia and vasospasm. “The abstracts are ranked by a scoring system developed by the Program Committee. We also call on leading stroke scientists outside the committee to grade the abstracts. We average the scores from each group,” Dr. Gorelick said. “In scoring the abstracts, the reviewers consider the type of study, the sample size in clinical studies, the innovativeness thurSday, february 21 Symposium 7:30 – 10:00 p.m. “Challenging Cases in Acute Blood Pressure Management” Hilton New Orleans Riverside Grand Ballroom A Sponsored by: PDL BioPharma, Inc. Supported by: PDL BioPharma, Inc. This is an invitation-only event Symposium 7:30 – 10:00 p.m. “Stroke Management Update: Research Highlights of 2007” Hilton New Orleans Riverside Salons C and D, 1st Floor Sponsored by: Boehringer Ingelhiem Supported by: Boehringer Ingelhiem Open to all attendees ISC Digest Preview is published by TriStar Publishing, Inc. as a service to the attendees of the International Stroke Conference. ®2008, TriStar Publishing, Inc. 7285 W. 132nd Street, Suite 300 Overland Park, KS 66213 Phone: (913) 491-4200 Fax: (913) 491-4202 www.tristarpub.com http://www.tristarpub.com

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