Annals of Neurology Journal - May 2012 - (Page 652k) DIGITAL ONLY Supplemental content for: Validation of the Charcot–Marie–Tooth Disease Pediatric Scale as an Outcome Measure of Disability (642–652) 8. Balance Bruininks-Oseretsky Test of Motor Proficiency, Second Edition (BOT-2) (NCS Pearson, Upper Saddle River, NJ, USA): Balance subtest. Background/Purpose: The BOT-2 is an individually administered test that uses engaging, goal-directed activities to measure a wide array of motor skills in individuals <21 years. We are using the BOT-2 subtest of balance. Tests of standing and walking balance include: standing with feet apart on a line (eyes open/closed); walking forward on a line and walking forward heel-to-toe on a line; standing on one leg on a line (eyes open/closed); standing on one leg on a balance beam (eyes open/closed); and standing heel-totoe on a balance beam.16 The BOT-2 incorporates age-equivalent normative data and is regarded as a reliable and valid measure of motor ability.17 Course set-up General Directions Perform using the portion of the running course from the ‘examiner throwing line’ to the ‘end line’ and the target on the wall (see diagram above). Place the target on the wall at the appropriate level for the child’s height, with the bottom of the target at the examiner’s eye level. For items using the balance beam, place the beam at the ‘end line’. For each item, conduct a second trial only if the child does not earn the maximum score on their first trial. Before administering each item, teach the task to the child using verbal and non-verbal directions as necessary to ensure the child’s understanding of the task. Tests should be performed barefoot and without an assistive device. If assistive devices are required (e.g. AFO) they should be clearly documented with footwear details, and repeated at follow-up. For those unable to perform Balance due to CMT severity, score 0 Points. See over the page for BOT-2 Balance Subtest Instructions: 11 © J Burns et al and the Inherited Neuropathies Consortium 2011 continued on next page Please note: Wiley-Blackwell are not responsible for the content or functionality of any supporting materials supplied by the authors. Any queries (other than missing material) should be directed to the corresponding author for the article. Table of Contents for the Digital Edition of Annals of Neurology Journal - May 2012 Annals of Neurology Journal - May 2012 Contents Multiple Sclerosis Drugs: Sticker Shock Genomic Testing Update Discoveries in Neuroscience Cerebrospinal Fluid Proteomics: A New Window for Understanding Human Demyelinating Disorders? Cell Therapy for Neonatal Hypoxia–Ischemia and Cerebral Palsy Implication of Perturbed Axoglial Apparatus in Early Pediatric Multiple Sclerosis Proteomic Pattern Analysis Discriminates Among Multiple Sclerosis–Related Disorders Rapid Communication: Thrombolysis With Recombinant Tissue Plasminogen Activator Under Dabigatran Anticoagulation in Experimental Stroke Symptomatic Intracranial Hemorrhage After Stroke Thrombolysis: The Sedan Score Validation of the Charcot–Marie–Tooth Disease Pediatric Scale as an Outcome Measure of Disability Childhood Socioeconomic Status and Adult Brain Size: Childhood Socioeconomic Status Influences Adult Hippocampal Size Excessive Daytime Sleepiness and Vascular Events: The Three City Study Dynamics of Hemispheric Dominance for Language Assessed by Magnetoencephalographic Imaging Anesthetics Isoflurane and Desflurane Differently Affect Mitochondrial Function, Learning, and Memory Losartan, a Therapeutic Candidate in Congenital Muscular Dystrophy: Studies in the Dy2j/dy2j Mouse Carotid Plaque Inflammation on 18f-Fluorodeoxyglucose Positron Emission Tomography Predicts Early Stroke Recurrence Homozygous Deletion of an Egr2 Enhancer in Congenital Amyelinating Neuropathy Hydrocarbon Solvent Exposure and Parkinson Disease Assessing Bioequivalence of Generic Antiepilepsy Drugs by Indirect Comparisons Reply Angiogenin Variation and Parkinson Disease Angiogenin, a Piece of the Complex Puzzle of Neurodegeneration Erratum Annals of Neurology Journal - May 2012 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurolog_importantinfo http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201310 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201309 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201308 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201307 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201306 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201305 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201304 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201303 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201302 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201301 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201212 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201211 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201210 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201209 http://www.nxtbook.com/nxtbooks/wiley/clinicalhighlights_2012 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201208 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201207 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201206 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201205 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201204 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201203 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201202 http://www.nxtbook.com/nxtbooks/wiley/annalsofneurology_201201 http://www.nxtbookMEDIA.com