Food Business News - February 11, 2014 - (Page 28)

HAVE CONFIDENCE IN THE LECITHIN YOU CHOOSE ORGANIC LECITHIN LECITHIN E T N NATURAL LECITHIN NON-GMO LECITHIN YOUR TRUSTED NAME IN INNOVATION FOR OVER 10 YEARS INGREDIENTS 320 East South Street P.O. Box 80 Cerro Gordo, Illinois 61818 217-763-9511 | 28 FOODBUSINESS NEWS ® Are designer fibers on the horizon? A newly-developed "designer" dietary fiber with an added potential prebiotic effect may eliminate the side effects of current treatment for irritable bowel syndrome (I.B.S.), which affects 10% to 20% of the population. A research collaboration between a gastroenterologist at Rush University, Chicago, and a carbohydrate chemist at Purdue University, West Lafayette, Ind., led to the development of the new product, a natural starch derived from a mixture of seaweed and starch in which the release of starch fiber in the gastrointestinal tract may be delayed, slowed and controlled to occur in the colon, rather than in the stomach and upper intestine. "This new product prevents the discomfort and bloating associated with current fiber therapies, while getting our new fiber into the colon and specifically distal colon where traditional fiber products typically do not reach and where many diseases of colon-like cancers develop," said Ece Mutlu, principal investigator in the phase II trial that began at Rush University this past month. In an earlier phase I study with 60 patients suffering from constipation, the new fiber was shown to be safe, better tolerated and with fewer side effects than currently available fiber treatments and it had a positive effect on intestinal microbiota composition by promoting the growth of "healthy" bacteria in the colon. "We wanted to create a fiber with a slow rate of fermentation to avoid rapid expansion of the gut and thus decrease the likelihood of common weight management. At the University of Laval, Quebec City, a study published in the British Journal of Nutrition showed certain strains of probiotics may help in weight loss and keeping the weight off. Studies have shown the intestinal flora of obese people differs from that of people who are not obese. The difference may be due to the fact that a diet high in fat and low in fiber promotes certain bacteria at the expense of others. Professor Angelo Tremblay from the University of Laval and his team tried to determine if the consumption of probiotics may help reset the balance of the intestinal microbiota in favor of bacteria that promote a healthy weight. To test the hypothesis, the researchers recruited 125 overweight men and women. The subjects underwent a 12-week weightloss diet, followed by a 12-week period aimed at maintaining body weight. Throughout the study, half the participants swallowed two pills daily containing probiotics from the Lactobacillus rhamnosus family, while the other half received a placebo. After the 12-week diet period, researchers observed an average weight loss of 9.7 lbs in women in the probiotic group and 5.7 lbs in the placebo group. No differences in weight loss were observed among males in the two groups. "We don't know why the probiotics didn't side effects of conventionally used fibers like bloating," said Ali Keshavarzian, professor and director of gastroenterology at Rush University. The fiber also is designed to produce a high level of a short chain fatty acid, butyrate in order to promote gut health and to have a prebiotic effect for it to be a supplemental treatment for I.B.S. The fiber is a targeted, controlled-release fiber that travels through the large intestine to be fermented by bacteria in the entire colon, including the descending (distal) colon where colon cancer, diverticulitis, ulcerative colitis and irritability commonly occur. The fiber may be designed to target different locations, according to the researchers. This enables the bacteria in the large intestine to receive nutrients from the fiber, which promotes overall gut health. "We worked closely with Purdue University food scientist Dr. Bruce Hamaker to develop well-tolerated fiber with targeted delivery to the entire colon that could promote 'gut health' and possibly prevent and treat colonic diseases where changes in the gut play a key role," Dr. Keshavarzian said. A $2.5 million federal grant to develop the fiber was given to Nutrabiotix L.L.C., which is based in the Purdue Research Park, and is commercializing the patented designer fiber created by Drs. Hamaker and Keshavarzian. Potential markets for the new fiber range between the dietary supplements category, functional foods and medical foods industries. FBN have any effect on men," Dr. Tremblay said. "It may be a question of dosage, or the study period may have been too short." After the 12-week maintenance period, the weight of the women in the placebo group remained stable but the probiotic group continued to lose weight, for a total of 11.5 lbs per person. The women consuming probiotics lost twice as much weight over the 24-week period of the study as the placebo group. The researchers also noted a drop in the appetite-regulating hormone leptin in the probiotic group, as well as a lower overall concentration of the intestinal bacteria related to obesity. Dr. Tremblay said probiotics may act by altering the permeability of the intestinal wall. By keeping certain pro-inflammatory molecules from entering the bloodstream, they may help prevent the chain reaction that leads to glucose intolerance, type 2 diabetes, and obesity. While the study focused on only one strain of Lactobacillus rhamnosus, Dr. Tremblay said other probiotics found in dairy products may have a similar effect. He emphasized the benefits of the bacteria are more likely to be observed in a favorable nutritional context that promotes lowfat and adequate fiber intake. FBN - Keith Nunes February 11, 2014

Table of Contents for the Digital Edition of Food Business News - February 11, 2014

Food Business News - February 11, 2014
Post to buy PowerBar from Nestle
Beverage ingredients in the spotlight
Beef prices are red hot
Table of Contents
Web Contents
Editorial - Cause marketing gaining momentum
Green Mountain, Coca-Cola form partnership
McDonald’s is learning less is more
F.D.A. proposes sanitary food transportation rule
Price increase still planned for Chipotle
Inside Tyson Foods’ prepared foods strategy
Beef, chicken drive gains for Tyson
Meat costs will hinder Hillshire in second half
Meijer to build dairy facility in Ohio
Hershey seeks to set new bar in spreads
Washington - Putting the new farm bill in focus
Health and Wellness - Digesting the additional benefits of gut health
Are designer fibers on the horizon?
Ingredient Innovations - Making cereal more satisfying
More satiety strategies
Beverage Business News - Beverage ingredients in the spotlight
New Food Products
Ingredient Market Trends - Weather woes continue to affect markets
Ingredient Markets
Supplier Innovations and News
Ad Index
Food Business in the News

Food Business News - February 11, 2014