Food Business News - February 10, 2015 - (Page 30)

Health and Wellness Health and Wellness On the cutting edge of digestive health Researchers are on the brink of identifying the mechanisms by which digestive health improves overall wellness report published this past November by the market research firm Packaged Facts highlighted the key trends and developments taking place in the market for functional foods and ingredients. Most notably, the report highlighted five categories of functional food ingredients manufacturers should pay attention to in 2015, including protein, omega-3 fatty acids, vitamin D, magnesium and microalgae. Conspicuously missing from the list were ingredients associated with digestive health. That may change in the coming years as more research not A 30 FOODBUSINESS NEWS ® only further identifies the benefits of digestive health, but also how those benefits are derived. The latter point has been a blind spot, but now several study results indicate researchers are on the cusp of identifying the mechanisms that associate digestive health with overall health outcomes. While much of the research has been done with mice, it is clear the results may translate to humans. For example, diet-induced changes in gut bacteria may alter susceptibility to an auto-inflammatory bone disease by modifying the immune response, according to a study conducted by researchers at St. Jude Children's Research Hospital in Memphis, Tenn. The findings appeared online in the journal Nature. The research provides insight into how the bacteria and other microorganisms that live in the intestines affect health. The microbes make up the intestinal microbiome, an ecosystem in the body that aids digestion and helps to "educate" the immune cells that guard against infection. Growing evidence suggests changes in the microbiome composition may contribute to development of diseases ranging from cancer to chronic inflammatory disorders such as multiple sclerosis, according to the researchers. The mechanisms involved, however, are poorly understood. "These results are exciting because they help to explain how environmental factors like diet can influence susceptibility to auto-inflammatory diseases," said the study's lead author Thirumala-Devi Kanneganti, Ph.D., a member of the St. Jude Department of Immunology. "While multiple lines of evidence have suggested that diet can impact human disease, the scientific mechanism involved was a mystery. Our results demonstrate that diet can influence immune-mediated disorders by shaping the composition of the gut microbiome, which our findings suggest play a role in immune regulation." The study was done in a mouse model of the inflammatory childhood bone disorder called chronic recurrent multifocal osteomyelitis, which leads to lesions, inflammation and pain in the bones of children. The mice involved in the study carry a mutation in a gene identified as Pstpip2 that leads to osteomyelitis early in life. The researchers showed that changing the nutritional composition of the animals' diets led to marked increases and decreases of certain intestinal bacteria. Affected bacteria included Prevotella, which have been implicated in causing osteomyelitis, arthritis, periodontal disease and other inflammatory disorders in humans. A diet that limited intestinal Prevotella growth protected the mutant mice from developing osteomyelitis. The same diet was associated with reduced February 10, 2015

Table of Contents for the Digital Edition of Food Business News - February 10, 2015

Food Business News - February 10, 2015
Hershey continues move into snack categories
Renewed school food fight looming on the horizon
Beverage Business News - Colorful ways to quench a thirst
Table of Contents
Web Contents
Editorial - Oil and currency moves should be seen as threats
McCormick eyes ambitious growth in year ahead
Dunkin’ to debut cold blended beverage platform
Campbell Soup in the midst of reorganizing
The future of shopper marketing
JBS USA plans expansion at Utah beef plant
Large MOM multiples
More tough times ahead for McDonald’s
Inside Wendy’s menu strategy
Chipotle on fire
Diamond acquires stake in potato chip maker
Market Insight - More cattle but beef prices still rising
Health and Wellness - On the cutting edge of digestive health
Ingredient Innovations - Backing up satiety benefits
Company Profile - Tyson Foods flying high
New Food Products
Ingredient Market Trends - Soybean oil market pulled lower, then higher
Ingredient Markets
Supplier Innovations and News
Ad Index
Food Business in the News

Food Business News - February 10, 2015