Vital Times 2017 - 70

sugammadex administration, rocuronium dose is 1.2 mg/
kg. After four hours, the dose returns to 0.6 mg/kg.
Although in the past there was concern about
hypersensitivity to sugammadex, it is rare. There have
been 15 reports of possible events, that usually occurred
within 5 minutes. The adverse effects of sugammadex
include bradycardia, abdominal pain, nausea & vomiting
and headache. Because of slower elimination of
rocuronium- sugammadex complex, sugammadex should
be in used with caution in renal insufficiency and avoided
in renal failure.
A hormonal contraceptive administered prior to
sugammadex will bind to it. According to the package
insert, a patient using a hormonal contraceptive must use
an additional, non-hormonal method of contraception
for 7 days following sugammadex administration.

DESIGNED FOR
RELIABILITY
AND ACCURACY.

Suggested Reading
1. Fortier LP. Anesth Analg. 2015;121:366
2. Murphy GS. Anesth Analg. 2013;117:133
3. Murphy GS. Anesthesiology. 2015;123:1322
4. Cedborg AI. Anesthesiology. 2014;120:312
5. Bulka CM. Anesthesiology. 2016;125:647
6. King M. Anesthesiology. 2000;93:1392
7. Baete S. Anesth Analg. 2017;124:1469
8. Apfelbaum JL. Anesthesiology. 2013;118:291
9. Thilen SR. Anesthesiology. 2012;117:964
10. Cooper RA. Br J Anaesth. 1993;71:222
11. McLean DJ. Anesthesiology. 2015;122:1201
12. Brull SJ. Anesthesiology. 2017;126:173
13. Jones RK. Anesthesiology. 2008;109:816
14. Carron M. J Clin Anesth. 2016;35:1
15. Ortiz-Gómez JR. Eur J Anaesthesiol. 2014;31:708
16. Shah D. J Clin Anesth. 2017;37:109
17. Lee C. Anesthesiology. 2009;110:1020

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70   | CSA Vital Times

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© 2017 Medtronic. All rights reserved. Medtronic,
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