Journal of Oral Implantology April 2012 - (Page 181)

CASE LETTER The Use of Leukocyte- and Platelet-Rich Fibrin During Immediate Postextractive Implantation and Loading for the Esthetic Replacement of a Fractured Maxillary Central Incisor Marco Del Corso, DDS1 Ziv Mazor, DDS2 James L. Rutkowski, DMD, PhD3 David M. Dohan Ehrenfest, DDS, PhD4* INTRODUCTION mplant-supported restoration of the maxillary anterior segment that is biologically, functionally, and esthetically acceptable following traumatic injuries in the maxillary anterior segment is always complex.1 Careful extraction2 of the fractured root, residual labial bone preservation, proper flap design, ideal positioning of the implant, appropriate softtissue contour, and the crown emergence are all important steps necessary to achieve a predictable, stable, functional, and esthetic success. However, healing of the tissues is always difficult to control and the development of new techniques and materials to improve these treatments is still necessary. 1 2 3 I Private practice, Turin, Italy. Private practice, Ra’anana, Israel. Clarion Research Group, Clarion, Penn. Department of Restorative Dentistry, State University of New York at Buffalo, Buffalo, NY. 4 LoB5 Unit, Research Center for Biomineralization Disorders, School of Dentistry, Chonnam National University, Gwangju, South Korea. Department of Stomatology, Oral Surgery, and Dental and MaxilloFacial Radiology, School of Dental Medicine, University of Geneva, Geneva, Switzerland. * Corresponding author, e-mail: DOI: 10.1563/AAID-JOI-D-12-CL.3802 The use of platelet concentrates is an interesting approach. Platelet concentrates for surgical use are widely used and continuously investigated in oral and maxillofacial surgery.3 The objective is to gather platelet growth factors and to inject them on a surgical site to stimulate the healing process. A significant percentage of the literature is focused on the platelet-rich plasma (PRP) families. PRP4–7 is a liquid platelet suspension often activated into a platelet-rich gel (like fibrin glues). Another technology called leukocyteand platelet-rich fibrin (L-PRF) allows for the preparation of strong fibrin membranes enriched with cells (activated platelets, leukocytes, circulating cells)8 and platelet growth factors.9 This autologous healing biomaterial is free of additives (no anticoagulant during blood harvest, no chemicals for activation), simple, inexpensive, and quick to prepare (15 minutes for all steps). This technique is specifically adapted to the practical needs in daily implant dentistry. Several articles have reported the use of these L-PRF membranes for the stimulation of bone and Journal of Oral Implantology 181

Table of Contents for the Digital Edition of Journal of Oral Implantology April 2012

Research Letters: A New Editorial Format for the Rapid Disclosure of Innovative Data and Concepts, Didactic Demonstrations, and Scientific Discussions
Effect of Defective Collagen Synthesis on Epithelial Implant Interface: Lathyritic Model in Dogs. An Experimental Preliminary Study
Presence of Aspartate Aminotransferase in Peri-Implant Crevicular Fluid With and Without Mucositis
Deformation of Implant Abutments After Framework Connection Using Strain Gauges
Implant-Retained Mandibular Bar-Supported Overlay Dentures: A Finite Element Stress Analysis of Four Different Bar Heights
The Efficacy of Mylohyoid Nerve Anesthesia in Dental Implant Placement at the Edetulous Posterior Mandibular Ridge
Metal-Ceramic Screw-Retained Implant Fixed Partial Denture With Intraoral Luted Framework to Improve Passive Fit
A Relaxed Implant Bed: Implants Placed After Two Weeks of Osteotomy With Immediate Loading: A One Year Clinical Trial
A Modified Technique for Removing a Failed Abutment Screw From an Implant With a Custom Guide Tube
Therapy for Missing Lower Medial Incisor by Means of Reduced Diameter Implants
Simplifying the Implant Treatment Plan for an Elderly Patient
The Use of Leukocyte- and Platelet-Rich Fibrin During Immediate Postextractive Implantation and Loading for the Esthetic Replacement of a Fractured Maxillary Central Incisor
Atraumatic Removal of an Asymptomatic Migrated Dental Implant Into the Maxillary Sinus: A Case Report
Tooth-Implant Connection: A Review

Journal of Oral Implantology April 2012