Journal of Oral Implantology September 2012 - (Page 449)

RESEARCH Histometric Analysis of Bone Repair in Bone-Implant Interface Using a Polylactic/Polyglycolic Acid Copolymer Associated With Implants in Rabbit Tibia Alexandre Rodrigues Freire, MSc1* ´ Ana Claudia Rossi, DDS1 Thallita Pereira Queiroz, PhD2 ´ssica Lemos Gulinelli, PhD2 Je ´ Francisley Avila Souza, PhD2 ´rio Roge Margonar, PhD3 ´ Idelmo Rangel Garcia-Junior, PhD2 Eduardo Hochuli-Vieira, PhD4 Roberta Okamoto, PhD5 The purpose of this study was to evaluate the association of the combination of polylactic/polyglycolic acid around implants installed with and without primary stability through the histometric analysis of bone-implant interface. We used male rabbits, each of which received 2 titanium implants in each tibial metaphysis. The animals were divided into 4 groups: control with primary stability (CPS), control without primary stability (C), polymer with primary stability (PPS), and polymer without primary stability (P). Euthanasia was performed at postoperative days 40 and 90. The pieces were embedded in resin, sectioned, scraped, and stained with alizarin red and Stevenel blue. Histometric analysis evaluated the linear extension of contact between the bone and implant surface on the implant collar (CIC) and contact between the bone and implant surface on the first thread (CFT). Also evaluated was the area of newly formed bone (ANB) in the first thread. The results showed that there was new bone formation in all groups and during all periods. At 40 days, the ANB was higher in the PPS group than in the P group (P , .001); the CFT was statistically higher in the CPS group than the PPS group (P , .001) and was higher in the CPS group than the C group (P , .001). At 40 and 90 days, the CIC was higher in the P group than in the C group (P , .001). In conclusion, the copolymer had biocompatibility, enhanced bone healing, and presented osteoconductive properties, thus raising the contact between bone and implant, even without primary stability. Key Words: dental implants, bone substitutes, osseointegration, bone regeneration. INTRODUCTION Department of Morphology, Piracicaba Dental School – ˜ UNICAMP, Piracicaba, Sao Paulo, Brazil. 2 Department of Surgery and Integrated Clinic, Faculty of ˜ Dentistry of Aracatuba – UNESP, Aracatuba, Sao Paulo, Brazil. ¸ ¸ 3 ˜ University Center of Araraquara – UNIARA, Araraquara, Sao Paulo, Brazil. 4 Department of Oral and Maxillofacial Surgery and Traumatol˜ ogy, Faculty of Dentistry of Araraquara – UNESP, Araraquara, Sao Paulo, Brazil. 5 Department of Basic Sciences, Faculty of Dentistry of Aracatu¸ ˜ ba, Sao Paulo, Brazil. * Corresponding author, e-mail: DOI: 10.1563/AAID-JOI-D-10-00102 1 he use of dental implants represents an important treatment for edentulous patients (partial or total); however, success depends on intimate contact of bone tissue with the implant, that is, bone integration. The implant remains in the receptor because of the presence of primary stability, and this has been identified as a prerequisite for Journal of Oral Implantology 449 T

Table of Contents for the Digital Edition of Journal of Oral Implantology September 2012

American Academy of Implant Dentistry Foundation Supports Basic and Clinical Research
Evaluation of 3- to 8-Year Treatment Outcomes and Success Rates With 6 Implant Brands in Partially Edentulous Patients
Histometric Analysis of Bone Repair in Bone-Implant Interface Using a Polylactic/ Polyglycolic Acid Copolymer Associated With Implants in Rabbit Tibia
Fold-Over Flap Technique for Developing the Facial Gingival Contour: A Case Report
Rehabilitation of the Atrophic Posterior Maxilla With Pterygoid Implants: A Review
Immediate Loading of Maxillary and Mandibular Implant-Supported Fixed Complete Dentures: A 1- to 10-Year Retrospective Study
Immediate Loading of Single Post-Extractive Implants in the Anterior Maxilla: 12-Month Results From a Multicenter Clinical Study
Immediate Implants After Enucleation of an Odontogenic Keratocyst: An Early Return to Function
Effects of Different Abutment Connection Designs on the Stress Distribution Around Five Different Implants: A 3-Dimensional Finite Element Analysis
Implant-Prosthetic Rehabilitation of a Patient with Nonsyndromic Oligodontia: A Clinical Report
Planning for Immediate Loading of Implant-Supported Prostheses: Literature Review
Development of a Rat Model of Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ)
Anorganic Bovine-Derived Hydroxyapatite vs β-Tricalcium Phosphate in Sinus Augmentation: A Comparative Histomorphometric Study
Peripheral Giant Cell Granuloma Associated With Dental Implants: Clinical Case and Literature Review
Bilateral Vertical Ridge Augmentation With Block Grafts and Guided Bone Regeneration in the Posterior Mandible: A Case Report
Cell Culture–Based Tissue Engineering as an Alternative to Bone Grafts in Implant Dentistry: A Literature Review

Journal of Oral Implantology September 2012