Journal of Oral Implantology February 2013 - (Page 73)

CLINICAL Clinical, Histological, and Histomorphometrical Analysis of Maxillary Sinus Augmentation Using Inorganic Bovine in Humans: Preliminary Results Joseph Bassil, PhD1* Nada Naaman, PhD2 Raed Lattouf, DDS, MSc3 Cynthia Kassis, DDS4 Sylvie Changotade, PhD5 Brigitte Baroukh, PhD6 Karim Senni, PhD, DSc7 Gaston Godeau, PhD, DSc8 The aim of the present study was to evaluate bone formation after maxillary sinus augmentation using bovine bone substitute material Bio-Oss alone by means of clinical, histological, and histomorphometrical examination of human biopsies. Deproteinized bovine bone (DPBB, Bio-Oss) was used to fill cavities after elevation of the sinus mucosa following major sinus pneumatization. Twenty patients with edentulous posterior maxillae were treated with 20 sinus augmentation procedures using a 2-stage technique. Residual lateral maxillary bone height was less than 3 mm. Forty-nine Straumann endosseous implants were used to complete the implant-prosthetic rehabilitation. Forty cylinder-shaped bone biopsies were taken from the augmented maxillary region 8 months after grafting during the second-stage surgery before implant placement. All implants were loaded 3 months after insertion, and no failures were recorded. Histomorphometrical analysis showed an average percentage of newly formed bone of 17.6% (62.8%) and a proportion of residual bone substitute material of 29.9% (64.9%) of the total biopsy area. Intimate contact between newly formed bone and Bio-Oss was detected along 28.2% (66.8%) of the particle surfaces. The results also showed that in all cases, the DPBB granules had been interconnected by bridges of vital newly formed bone. Inorganic bovine bone appears to be biocompatible and osteoconductive, and it can be used with success as a bone substitute in maxillary sinus augmentation procedures. Key Words: histomorphometrical analysis, inorganic bovine bone, bone graft 1 Department of Oral Surgery, Faculty of Dental Medicine, St Joseph University, Beirut, Lebanon. 2 Department of Periodontology, Faculty of Dental Medicine, St Joseph University, Beirut, Lebanon. 3 Department of Oral Surgery, St Joseph University, Beirut, Lebanon. 4 Department of Restorative and Esthetic Dentistry, Faculty of Dental Medicine, St Joseph University, Beirut, Lebanon. 5 ´ ` ´ ´ Laboratoire de Biomate riaux et Polyme res de Spe cialite , ´ Universite Paris, Bobigny, France. 6 ´ Laboratoire sur la Reparation et les Remodelages oro-faciaux, ´ ´ Faculte de Chirurgie Dentaire, Universite Paris, Montrouge, France. 7 ´ Innovation Department, Seadev-Fermensys, Plouzane, France, ´ ` ´ ´ and Laboratoire de Biomateriaux et Polymeres de Specialite, ´ Universite Paris, Bobigny France. 8 ´ ´ Faculte de Chirurgie Dentaire, Universite Paris, Montrouge, France. * Corresponding author, e-mail: joe.bassil@yahoo.fr DOI: 10.1563/AAID-JOI-D-11-00012 INTRODUCTION T he placement of implants in highly atrophic maxillae continues to be a major challenge in implant dentistry. One of the preferred options to resolve this problem is sinus floor elevation, which involves lifting the sinus floor and packing the space created with grafting material to provide adequate support for implants. From the various materials available for sinus grafting, autogenous bone is considered the gold standard because of its high biocompatibility, in addition to its osteoconductive, osteoinductive, and osteogenic potential.1,2 Journal of Oral Implantology 73

Table of Contents for the Digital Edition of Journal of Oral Implantology February 2013

Could the Fountain of Youth Be All in Your Bones?
Vertical Bone Augmentation With Simultaneous Implant Placement Using Particulate
Evaluation of the Bone Healing Process Utilizing Platelet-Rich Plasma Activated by Thrombin
Effect of Model Parameters on Finite Element Analysis of Micromotions in Implant Dentistry
Peri-Implant Defect Augmentation With Autogenous Bone: A Study in Beagle Dogs
Would Nitric Oxide be an Effective Marker for Earlier Stages of Peri-Implant Disease? An
The Effect of Different Surface Treatments on Cement-Retained Implant-Supported
Effect of Rotating Osteotomes on Primary Implant Stability—An In Vitro Investigation
Horizontal Augmentation Through the Ridge-Split Procedure: A Predictable Surgical
The Bis-Acryl Stent
Clinical, Histological, and Histomorphometrical Analysis of Maxillary Sinus Augmentation
A Technique to Salvage a Single Implant-Supported Fixed Dental Prosthesis Having a
Ridge Expansion and Immediate Placement With Piezosurgery and Screw Expanders in
Pterygoid Implants for Maxillofacial Rehabilitation of a Patient With a Bilateral Maxillectomy
Technology in Maxillary Premolar Region: A New Strategy for Soft Tissue Management
Fracture of Anterior Iliac Crest Following Bone Graft Harvest in an Anorexic Patient: Case
A Technique for Constructing a New Maxillary Overdenture to a Nonretrievable Implant
Edentulous Maxillary Arch Fixed Implant Rehabilitation Using a Hybrid Prosthesis Made of

Journal of Oral Implantology February 2013