APR January/February 2022 - 66

» FORMULATION AND DEVELOPMENT
»
using barcoding features to record equipment inventory and take
advantage of the handsfree features by adding comments and
observations using the VR headset. An additional feature that is only
possible using VR technology is remote guidance. In our demo, we
were able to independently onboard a novice user into the Tandem
environment and use the RealWear headset to remotely provide
guidance through a laboratory process despite no prior experience
with the technology. The RealWear device was comfortable and had
excellent video and photo quality.
Collectively, we feel believe Apprentice technology has the potential
to enable our digital vision for managing the process of an analytical
Feature
Method Guidance
Table 1. Digital Workflow Tool Features
Technology
Application
* Apprentice Methods
* Barcode
* RealWear Headset
* Tablet
Preparative Calculations
Simple Equipment
Capture
Recording Materials
and Equipment
Remote Guidance
* Apprentice Methods
* RealWear Headset
* Tablet
* Apprentice Methods
* RealWear Headset
* Apprentice Methods
* Barcode
* RealWear Headset
* Apprentice Tandem
* RealWear Headset
Step by step workflow description
and guidance for consistent execution
and tracking of steps
Information and step confirmation
achieved by barcode
Calculations related to experiment
scale completed with simple data
entry or voice command
Values entered by simple data entry
or captured by photo or video
Capture experimental materials
and equipment hands free using a
barcode reader.
Remote guidance between lab
personnel and deskside support for
virtual training and troubleshooting
The technical transfer of projects, methods, data and tests between
Eli Lilly divisions can be a lengthy and resource intensive process (e.g.,
between development and manufacturing). The large number of
computer-based systems and individuals (scientists and engineers)
involved in a project provide complications to a process that is already
highly detailed and regulated.
Eli Lilly leveraged wearables delivered by Apprentice and manufactured
by RealWear to capture information that was then transferred
to Varya's Iota platform. Iota allowed Lilly to build " notebooks "
of research, experiments and results with few limitations. These
notebooks included audio, video and images captured by the headworn
mobile devices. Through this interface Lilly was able to capture,
locate, organize and perform analytics on this information to share
and transfer to other parts of the Lilly organization. Iota's seamless
laboratory workflow. One area of development that will make this
promising technology come to fruition is flexibility in the manuals
feature where steps can be easily edited within a document and
repurposed to procedures with similar steps. To complete our vision, we
will look to integrate the experimental metadata from the Apprentice
environment with analytical instrument data in a structured cloudbased
environment. Once accomplished, analysis and reporting
outputs can be automated independently or in conjunction with a
suitable ELN.
Use Case: Technical Transfer and
Third-Party Organizations
Figure 5. Apprentice Annotated SOP
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APR January/February 2022

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